Myokine mediated muscle-kidney crosstalk suppresses metabolic reprogramming and fibrosis in damaged kidneys

PTH/PTHrP Receptor Mediates Cachexia in Models of Kidney Failure and Cancer

(2016) Serkan Kir et al.   Cell Metabolism

PGC1α drives NAD biosynthesis linking oxidative metabolism to renal protection

(2016) Mei T. Tran et al.   NATURE

TGF-β: the master regulator of fibrosis

(2016) Xiao-ming Meng et al.   Nature Reviews Nephrology

Skeletal muscle as an endocrine organ: PGC-1α, myokines and exercise

(2015) Svenia Schnyder et al.   BONE

Loss of PTEN promotes podocyte cytoskeletal rearrangement, aggravating diabetic nephropathy

(2015) Jamie S Lin et al.   JOURNAL OF PATHOLOGY

JAK3/STAT6 Stimulates Bone Marrow-Derived Fibroblast Activation in Renal Fibrosis

(2015) J. Yan et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

CKD Stimulates Muscle Protein Loss Via Rho-associated Protein Kinase 1 Activation

(2015) H. Peng et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Exercise Capacity and Risk of Chronic Kidney Disease in US Veterans: A Cohort Study

(2015) Peter Kokkinos et al.   MAYO CLINIC PROCEEDINGS

Understanding the mechanisms of kidney fibrosis

(2015) Dong Zhou et al.   Nature Reviews Nephrology

Skeletal Muscle PGC-1α1 Modulates Kynurenine Metabolism and Mediates Resilience to Stress-Induced Depression

(2014) Leandro Z. Agudelo et al.   CELL

Renal Cortical Pyruvate Depletion during AKI

(2014) R. A. Zager et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Blood Kidney Injury Molecule-1 Is a Biomarker of Acute and Chronic Kidney Injury and Predicts Progression to ESRD in Type I Diabetes

(2014) V. S. Sabbisetti et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Defective fatty acid oxidation in renal tubular epithelial cells has a key role in kidney fibrosis development

(2014) Hyun Mi Kang et al.   NATURE MEDICINE

Dysfunctional fatty acid oxidation in renal fibrosis

(2014) Susan J. Allison   Nature Reviews Nephrology

Irisin Stimulates Browning of White Adipocytes Through Mitogen-Activated Protein Kinase p38 MAP Kinase and ERK MAP Kinase Signaling

(2013) Y. Zhang et al.   DIABETES

Defective glucose metabolism in polycystic kidney disease identifies a new therapeutic strategy

(2013) Isaline Rowe et al.   NATURE MEDICINE

A PGC1-α-dependent myokine that drives brown-fat-like development of white fat and thermogenesis

(2012) Pontus Boström et al.   NATURE

Muscles, exercise and obesity: skeletal muscle as a secretory organ

(2012) Bente K. Pedersen et al.   Nature Reviews Endocrinology

Hexokinase: a novel sugar kinase coupled to renal epithelial cell survival

(2011) R. Brooks Robey   KIDNEY INTERNATIONAL

Bioenergetic function in cardiovascular cells: The importance of the reserve capacity and its biological regulation

(2010) Brian E. Sansbury et al.   CHEMICO-BIOLOGICAL INTERACTIONS

T RI/Alk5-independent T RII signaling to ERK1/2 in human skin cells according to distinct levels of T RII expression

(2010) B. Bandyopadhyay et al.   JOURNAL OF CELL SCIENCE

Angiotensin II overcomes strain-dependent resistance of rapid CKD progression in a new remnant kidney mouse model

(2010) Asada Leelahavanichkul et al.   KIDNEY INTERNATIONAL

Single-molecule imaging reveals transforming growth factor- -induced type II receptor dimerization

(2009) W. Zhang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Prevalence of CKD in the United States: A Sensitivity Analysis Using the National Health and Nutrition Examination Survey (NHANES) 1999-2004

(2008) Jon J. Snyder et al.   AMERICAN JOURNAL OF KIDNEY DISEASES

The role of exercise and PGC1α in inflammation and chronic disease

(2008) Christoph Handschin et al.   NATURE