A novel copper chelator for the suppression of colorectal cancer

Copper induces cell death by targeting lipoylated TCA cycle proteins

(2022) Peter Tsvetkov et al.   SCIENCE

Role of Copper on Mitochondrial Function and Metabolism

(2021) Lina M. Ruiz et al.   Frontiers in Molecular Biosciences

Modulation of Intracellular Copper Levels as the Mechanism of Action of Anticancer Copper Complexes: Clinical Relevance

(2021) Maria V. Babak et al.   Biomedicines

Inflammation mobilizes copper metabolism to promote colon tumorigenesis via an IL-17-STEAP4-XIAP axis

(2020) Yun Liao et al.   Nature Communications

2-Deoxy-Rh2: A novel ginsenoside derivative, as dual-targeting anti-cancer agent via regulating apoptosis and glycolysis

(2020) Huan Gao et al.   BIOMEDICINE & PHARMACOTHERAPY

Co-delivery of Cu(I) chelator and chemotherapeutics as a new strategy for tumor theranostic

(2020) Tao Sun et al.   JOURNAL OF CONTROLLED RELEASE

The molecular mechanisms of copper metabolism and its roles in human diseases

(2020) Ji Chen et al.   PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY

Copper bioavailability is a KRAS-specific vulnerability in colorectal cancer

(2020) Léo Aubert et al.   Nature Communications

Copper metabolism as a unique vulnerability in cancer

(2020) Vinit C. Shanbhag et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Synthesis and evaluation of novel GSK-3β inhibitors as multifunctional agents against Alzheimer's disease

(2019) Xiao-Long Shi et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Effects of Copper Chelation on BRAFV600E Positive Colon Carcinoma Cells

(2019) Silvia Baldari et al.   Cancers

Copper Deficiency: Causes, Manifestations, and Treatment

(2019) Marco Altarelli et al.   NUTRITION IN CLINICAL PRACTICE

The mitochondrion: a central architect of copper homeostasis

(2017) Zakery N. Baker et al.   Metallomics

Triethylenetetramine modulates polyamine and energy metabolism and inhibits cancer cell proliferation

(2016) M. T. Hyvonen et al.   BIOCHEMICAL JOURNAL

Copper dyshomoeostasis in Parkinson's disease: implications for pathogenesis and indications for novel therapeutics

(2016) K. M. Davies et al.   CLINICAL SCIENCE

Curcumin is a biologically active copper chelator with antitumor activity

(2016) Wei Zhang et al.   PHYTOMEDICINE

Spherical Cancer Models in Tumor Biology

(2015) Louis-Bastien Weiswald et al.   NEOPLASIA

The promise of copper lowering therapy with tetrathiomolybdate in the cure of cancer and in the treatment of inflammatory disease

(2014) George J. Brewer   JOURNAL OF TRACE ELEMENTS IN MEDICINE AND BIOLOGY

Penicillamine Revisited: Historic Overview and Review of the Clinical Uses and Cutaneous Adverse Effects

(2013) Rim Ishak et al.   AMERICAN JOURNAL OF CLINICAL DERMATOLOGY

Tetrathiomolybdate-associated copper depletion decreases circulating endothelial progenitor cells in women with breast cancer at high risk of relapse

(2013) S. Jain et al.   ANNALS OF ONCOLOGY

Iron and Copper in Mitochondrial Diseases

(2013) Wenjing Xu et al.   Cell Metabolism

Bioavailable copper modulates oxidative phosphorylation and growth of tumors

(2013) S. Ishida et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Metal dyshomeostasis and oxidative stress in Alzheimer’s disease

(2012) Mark A. Greenough et al.   NEUROCHEMISTRY INTERNATIONAL

Advances in metal-induced oxidative stress and human disease

(2011) Klaudia Jomova et al.   TOXICOLOGY

Tetrathiomolybdate Inhibits Copper Trafficking Proteins Through Metal Cluster Formation

(2009) H. M. Alvarez et al.   SCIENCE

Elevated copper and oxidative stress in cancer cells as a target for cancer treatment

(2008) Anshul Gupte et al.   CANCER TREATMENT REVIEWS