Artemisinin exerts a protective effect in the MPTP mouse model of Parkinson's disease by inhibiting microglial activation via the TLR4/Myd88/NF‐KB pathway

Dihydroartemisinin suppresses renal fibrosis in mice by inhibiting DNA-methyltransferase 1 and increasing Klotho

(2022) Wei Zhou et al.   ACTA PHARMACOLOGICA SINICA

Transplantation of Roxadustat‐preconditioned bone marrow stromal cells improves neurological function recovery through enhancing grafted cell survival in ischemic stroke rats

(2022) Jiayu Chen et al.   CNS Neuroscience & Therapeutics

Nano-organization of spontaneous GABAergic transmission directs its autonomous function in neuronal signaling

(2022) Natalie J. Guzikowski et al.   Cell Reports

Exploring the Paradox of COVID-19 in Neurological Complications with Emphasis on Parkinson’s and Alzheimer’s Disease

(2022) Sachchida Nand Rai et al.   Oxidative Medicine and Cellular Longevity

Artemisinin analogue SM934 protects against lupus-associated antiphospholipid syndrome via activation of Nrf2 and its targets

(2021) Zemin Lin et al.   Science China-Life Sciences

CD4 T cells mediate brain inflammation and neurodegeneration in a mouse model of Parkinson disease

(2021) Gregory P Williams et al.   BRAIN

Interaction of artemisinin protects the activity of antioxidant enzyme catalase: A biophysical study

(2021) Rashmi R. Samal et al.   INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

Artemisinin attenuated oxidative stress and apoptosis by inhibiting autophagy in MPP+-treated SH-SY5Y cells

(2021) Junqiang Yan et al.   Journal of Biological Research-Thessaloniki

Artemisinin improves neurocognitive deficits associated with sepsis by activating the AMPK axis in microglia

(2021) Shao-peng Lin et al.   ACTA PHARMACOLOGICA SINICA

Oxidative stress and regulated cell death in Parkinson’s disease

(2021) P.A. Dionísio et al.   AGEING RESEARCH REVIEWS

Sevoflurane preconditioning protects experimental ischemic stroke by enhancing anti‐inflammatory microglia/macrophages phenotype polarization through GSK‐3β/Nrf2 pathway

(2021) Min Cai et al.   CNS Neuroscience & Therapeutics

FBXO10 prevents chronic unpredictable stress‐induced behavioral despair and cognitive impairment through promoting RAGE degradation

(2021) Jiacen Li et al.   CNS Neuroscience & Therapeutics

Critical Roles of Lysophospholipid Receptors in Activation of Neuroglia and Their Neuroinflammatory Responses

(2021) Bhakta Prasad Gaire et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Immune cell compartmentalization for brain surveillance and protection

(2021) Tommaso Croese et al.   NATURE IMMUNOLOGY

Parkinson disease-associated cognitive impairment

(2021) Dag Aarsland et al.   Nature Reviews Disease Primers

Single-cell sequencing of human midbrain reveals glial activation and a Parkinson-specific neuronal state

(2021) Semra Smajić et al.   BRAIN

Sensory Neuron TLR4 mediates the development of nerve-injury induced mechanical hypersensitivity in female mice

(2021) Thomas A. Szabo-Pardi et al.   BRAIN BEHAVIOR AND IMMUNITY

Association between inflammatory bowel diseases and Parkinson’s disease: systematic review and meta-analysis

(2021) Zheng-Bing Xiang et al.   Neural Regeneration Research

TLR4 and AT1R mediate blood-brain barrier disruption, neuroinflammation, and autonomic dysfunction in spontaneously hypertensive rats

(2021) Francesca E. Mowry et al.   PHARMACOLOGICAL RESEARCH

Modeling alpha-synuclein pathology in a human brain-chip to assess blood-brain barrier disruption

(2021) Iosif Pediaditakis et al.   Nature Communications

Therapeutic Potential of Vital Transcription Factors in Alzheimer’s and Parkinson’s Disease With Particular Emphasis on Transcription Factor EB Mediated Autophagy

(2021) Sachchida Nand Rai et al.   Frontiers in Neuroscience

Advancement in the modelling and therapeutics of Parkinson’s disease

(2020) Sachchida Nand Rai et al.   JOURNAL OF CHEMICAL NEUROANATOMY

Epithelial TLR4 signaling activates DUOX2 to induce microbiota-driven tumorigenesis

(2020) Juan F. Burgueño et al.   GASTROENTEROLOGY

Meningeal γδ T cells regulate anxiety-like behavior via IL-17a signaling in neurons

(2020) Kalil Alves de Lima et al.   NATURE IMMUNOLOGY

Association of inflammatory factors and aging in Parkinson's disease

(2020) Hong Jin et al.   NEUROSCIENCE LETTERS

Microglia modulate neurodegeneration in Alzheimer’s and Parkinson’s diseases

(2020) Tim Bartels et al.   SCIENCE

Transcriptomic and clonal characterization of T cells in the human central nervous system

(2020) Jenna L. Pappalardo et al.   Science Immunology

Structural optimization and biological evaluation for novel artemisinin derivatives against liver and ovarian cancers

(2020) Yu Zhou et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Farrerol attenuates MPP+ -induced inflammatory response by TLR4 signaling in a microglia cell line

(2019) Bei Cui et al.   PHYTOTHERAPY RESEARCH

Negative regulation of glial Tim-3 inhibits the secretion of inflammatory factors and modulates microglia to antiinflammatory phenotype after experimental intracerebral hemorrhage in rats

(2019) Zhou-Qing Chen et al.   CNS Neuroscience & Therapeutics

Focal TLR4 activation mediates disturbed flow-induced endothelial inflammation

(2019) Dan Qu et al.   CARDIOVASCULAR RESEARCH

Transplantation of Nurr1-overexpressing neural stem cells and microglia for treating parkinsonian rats

(2019) Yuan Qian et al.   CNS Neuroscience & Therapeutics

Canadian guideline for Parkinson disease

(2019) David Grimes et al.   CANADIAN MEDICAL ASSOCIATION JOURNAL

Impaired cellular bioenergetics caused by GBA1 depletion sensitizes neurons to calcium overload

(2019) Nicoletta Plotegher et al.   CELL DEATH AND DIFFERENTIATION

TLR4 (Toll-Like Receptor 4) Mediates the Development of Intracranial Aneurysm Rupture

(2019) Kazuha Mitsui et al.   HYPERTENSION

Artemisinin Prevents Glutamate-Induced Neuronal Cell Death Via Akt Pathway Activation

(2018) Shao-Peng Lin et al.   Frontiers in Cellular Neuroscience

Artemisinin protects PC12 cells against β-amyloid-induced apoptosis through activation of the ERK1/2 signaling pathway

(2017) Zhiwen Zeng et al.   Redox Biology

TLR4 Signaling in MPP+-Induced Activation of BV-2 Cells

(2016) Peng Zhou et al.   NEURAL PLASTICITY

Microglia Development and Function

(2014) Debasis Nayak et al.   Annual Review of Immunology

Toxicity of the antimalarial artemisinin and its dervatives

(2010) Thomas Efferth et al.   CRITICAL REVIEWS IN TOXICOLOGY