Empagliflozin inhibits excessive autophagy through the AMPK/GSK3β signalling pathway in diabetic cardiomyopathy
Published 2023 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Empagliflozin inhibits excessive autophagy through the AMPK/GSK3β signalling pathway in diabetic cardiomyopathy
Authors
Keywords
-
Journal
CARDIOVASCULAR RESEARCH
Volume -, Issue -, Pages -
Publisher
Oxford University Press (OUP)
Online
2023-01-10
DOI
10.1093/cvr/cvad009
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Sex‐related differential susceptibility to ponatinib cardiotoxicity and differential modulation of the Notch1 signalling pathway in a murine model
- (2022) Rosalinda Madonna et al. JOURNAL OF CELLULAR AND MOLECULAR MEDICINE
- SIRT6 mediates MRTF-A deacetylation in vascular endothelial cells to antagonize oxLDL-induced ICAM-1 transcription
- (2022) Shan Huang et al. Cell Death Discovery
- Inhibition of platelet-derived growth factor C and their receptors additionally increases doxorubicin effects in triple-negative breast cancer cells
- (2021) Sangmin Kim et al. EUROPEAN JOURNAL OF PHARMACOLOGY
- Empagliflozin Attenuates Non-Alcoholic Fatty Liver Disease (NAFLD) in High Fat Diet Fed ApoE(-/-) Mice by Activating Autophagy and Reducing ER Stress and Apoptosis
- (2021) Narjes Nasiri-Ansari et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Empagliflozin Alleviates Hepatic Steatosis by Activating the AMPK-TET2-Autophagy Pathway in vivo and in vitro
- (2021) Ting Li et al. Frontiers in Pharmacology
- Empagliflozin alleviates ethanol‐induced cardiomyocyte injury through inhibition of mitochondrial apoptosis via a SIRT1/PTEN/Akt pathway
- (2021) Ge Tian et al. CLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY
- The SGLT2 inhibitor empagliflozin negatively regulates IL-17/IL-23 axis-mediated inflammatory responses in T2DM with NAFLD via the AMPK/mTOR/autophagy pathway
- (2021) Ziyu Meng et al. INTERNATIONAL IMMUNOPHARMACOLOGY
- Sodium–Glucose CoTransporter-2 Inhibitor Empagliflozin Ameliorates Sunitinib-Induced Cardiac Dysfunction via Regulation of AMPK–mTOR Signaling Pathway–Mediated Autophagy
- (2021) Changzhen Ren et al. Frontiers in Pharmacology
- Autophagy in the diabetic heart: A potential pharmacotherapeutic target in diabetic cardiomyopathy
- (2021) Saikat Dewanjee et al. AGEING RESEARCH REVIEWS
- Connexin 43 and Connexin 26 Involvement in the Ponatinib-Induced Cardiomyopathy: Sex-Related Differences in a Murine Model
- (2021) Rosalinda Madonna et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Subcellular Localization of Connexin 26 in Cardiomyocytes and in Cardiomyocyte-Derived Extracellular Vesicles
- (2021) Alessandra Falleni et al. MOLECULES
- Empagliflozin nanoparticles attenuates type2 diabetes induced cognitive impairment via oxidative stress and inflammatory pathway in high fructose diet induced hyperglycemic mice
- (2021) Tahira Khan et al. NEUROCHEMISTRY INTERNATIONAL
- Co‐expression of glycosylated aquaporin‐1 and transcription factor NFAT5 contributes to aortic stiffness in diabetic and atherosclerosis‐prone mice
- (2020) Rosalinda Madonna et al. JOURNAL OF CELLULAR AND MOLECULAR MEDICINE
- Deacetylation of MRTF-A by SIRT1 defies senescence induced down-regulation of collagen type I in fibroblast cells
- (2020) Yuyu Yang et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE
- Simulated hyperglycemia impairs insulin signaling in endothelial cells through a hyperosmolar mechanism
- (2020) Rosalinda Madonna et al. VASCULAR PHARMACOLOGY
- Empagliflozin reduces the senescence of cardiac stromal cells and improves cardiac function in a murine model of diabetes
- (2020) Rosalinda Madonna et al. JOURNAL OF CELLULAR AND MOLECULAR MEDICINE
- Effect of Empagliflozin on Cardiovascular and Renal Outcomes in Patients With Heart Failure by Baseline Diabetes Status
- (2020) Stefan D. Anker et al. CIRCULATION
- Transplantation of telomerase/myocardin-co-expressing mesenchymal cells in the mouse promotes myocardial revascularization and tissue repair
- (2020) Rosalinda Madonna et al. VASCULAR PHARMACOLOGY
- Cross your heart? Collagen cross-links in cardiac health and disease
- (2020) Lily S. Neff et al. CELLULAR SIGNALLING
- Ponatinib: a novel multi-tyrosine kinase inhibitor against human malignancies
- (2019) Fiona H Tan et al. OncoTargets and Therapy
- Mitophagy Is Essential for Maintaining Cardiac Function During High Fat Diet-Induced Diabetic Cardiomyopathy
- (2019) Mingming Tong et al. CIRCULATION RESEARCH
- Regulation of SRF protein stability by an autophagy-dependent pathway
- (2019) Jinque Luo et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Empagliflozin reduces the levels of CD36 and cardiotoxic lipids while improving autophagy in the hearts of Zucker diabetic fatty rats
- (2019) Alana Aragón-Herrera et al. BIOCHEMICAL PHARMACOLOGY
- Low‐dose empagliflozin as adjunct‐to‐insulin therapy in type 1 diabetes: A valid modelling and simulation analysis to confirm efficacy
- (2019) Bruce A. Perkins et al. DIABETES OBESITY & METABOLISM
- Connexin 26 Expression in Mammalian Cardiomyocytes
- (2018) S. Moscato et al. Scientific Reports
- Empagliflozin as Adjunctive to Insulin Therapy in Type 1 Diabetes: The EASE Trials
- (2018) Julio Rosenstock et al. DIABETES CARE
- Astrocyte elevated gene-1 induces autophagy in diabetic cardiomyopathy through upregulation of KLF4
- (2018) Lichun Zhao et al. JOURNAL OF CELLULAR BIOCHEMISTRY
- The novel relationship between Sirt3 and autophagy in myocardial ischemia-reperfusion
- (2018) Yitian Zheng et al. JOURNAL OF CELLULAR PHYSIOLOGY
- Curcumin protects against diabetic cardiomyopathy by promoting autophagy and alleviating apoptosis
- (2018) Qing Yao et al. JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY
- Autophagy was involved in the protective effect of metformin on hyperglycemia-induced cardiomyocyte apoptosis and Connexin43 downregulation in H9c2 cells
- (2017) Guang-Yu Wang et al. International Journal of Medical Sciences
- Connexins in Cardiovascular and Neurovascular Health and Disease: Pharmacological Implications
- (2017) Luc Leybaert et al. PHARMACOLOGICAL REVIEWS
- SIRT2 gene has a classic SRE element, is a downstream target of serum response factor and is likely activated during serum stimulation
- (2017) Xiaomin Zhang et al. PLoS One
- Connexins: substrates and regulators of autophagy
- (2016) Jegan Iyyathurai et al. BMC CELL BIOLOGY
- High glucose-induced hyperosmolarity contributes to COX-2 expression and angiogenesis: implications for diabetic retinopathy
- (2016) Rosalinda Madonna et al. Cardiovascular Diabetology
- Autophagic adaptations in diabetic cardiomyopathy differ between type 1 and type 2 diabetes
- (2015) Hiromitsu Kanamori et al. Autophagy
- Autophagy and oxidative stress in cardiovascular diseases
- (2015) Yu Mei et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE
- H9c2 and HL-1 cells demonstrate distinct features of energy metabolism, mitochondrial function and sensitivity to hypoxia-reoxygenation
- (2015) Andrey V. Kuznetsov et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH
- Too much or not enough of a good thing — The Janus faces of autophagy in cardiac fuel and protein homeostasis
- (2015) Jun Ren et al. JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY
- Empagliflozin, Cardiovascular Outcomes, and Mortality in Type 2 Diabetes
- (2015) Bernard Zinman et al. NEW ENGLAND JOURNAL OF MEDICINE
- Gene Expression Profiling of H9c2 Myoblast Differentiation towards a Cardiac-Like Phenotype
- (2015) Ana F. Branco et al. PLoS One
- Phosphorylation of AKT: a Mutational Analysis.
- (2015) Jonathan R. Hart et al. Oncotarget
- Cardiomyocyte glycophagy is regulated by insulin and exposure to high extracellular glucose
- (2014) Kimberley M. Mellor et al. AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY
- Co-Activation of Nuclear Factor-κB and Myocardin/Serum Response Factor Conveys the Hypertrophy Signal of High Insulin Levels in Cardiac Myoblasts
- (2014) Rosalinda Madonna et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Connexins modulate autophagosome biogenesis
- (2014) Eloy Bejarano et al. NATURE CELL BIOLOGY
- Alterations in connexin 43 during diabetic cardiomyopathy: Competition of tyrosine nitration versus phosphorylation 在糖尿病心肌病中间隙连接蛋白43的变化:酪氨酸硝化作用与磷酸化作用的竞争
- (2014) Mandar S. Joshi et al. Journal of Diabetes
- Role of microangiopathy in diabetic cardiomyopathy
- (2013) Adriana Adameova et al. HEART FAILURE REVIEWS
- Dissociation of Bcl-2-Beclin1 Complex by Activated AMPK Enhances Cardiac Autophagy and Protects Against Cardiomyocyte Apoptosis in Diabetes
- (2012) C. He et al. DIABETES
- Aldehyde dehydrogenase 2 (ALDH2) rescues myocardial ischaemia/reperfusion injury: role of autophagy paradox and toxic aldehyde
- (2010) Heng Ma et al. EUROPEAN HEART JOURNAL
- Role of autophagy in heart failure associated with aging
- (2010) Guido R. Y. De Meyer et al. HEART FAILURE REVIEWS
- Impact of long-term caloric restriction on cardiac senescence: Caloric restriction ameliorates cardiac diastolic dysfunction associated with aging
- (2010) Ken Shinmura et al. JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY
Create your own webinar
Interested in hosting your own webinar? Check the schedule and propose your idea to the Peeref Content Team.
Create NowBecome a Peeref-certified reviewer
The Peeref Institute provides free reviewer training that teaches the core competencies of the academic peer review process.
Get Started