SUMOylation of TUFT1 is essential for gastric cancer progression through AKT / mTOR signaling pathway activation

MicroRNA-145 regulates the proliferation of the human gastric cancer cells by targeting tuftelin 1 (TUFT1)

(2022) Pei Meng et al.   ACTA BIOCHIMICA POLONICA

Ginkgoic acid impedes gastric cancer cell proliferation, migration and EMT through inhibiting the SUMOylation of IGF-1R

(2021) Dongtao Liu et al.   CHEMICO-BIOLOGICAL INTERACTIONS

Global cancer statistics 2020: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries

(2021) Hyuna Sung et al.   CA-A CANCER JOURNAL FOR CLINICIANS

Emerging Roles of MHC Class I Region-Encoded E3 Ubiquitin Ligases in Innate Immunity

(2021) Xiuzhi Jia et al.   Frontiers in Immunology

BRD9 inhibition promotes PUMA-dependent apoptosis and augments the effect of imatinib in gastrointestinal stromal tumors

(2021) Jianfeng Mu et al.   Cell Death & Disease

Opposing biological functions of the cytoplasm and nucleus DAXX modified by SUMO-2/3 in gastric cancer

(2020) Chenbin Chen et al.   Cell Death & Disease

Downregulation of TRIM27 suppresses gastric cancer cell proliferation via inhibition of the Hippo-BIRC5 pathway

(2020) Yangyang Yao et al.   PATHOLOGY RESEARCH AND PRACTICE

Bromodomain-containing protein 9 promotes the growth and metastasis of human hepatocellular carcinoma by activating the TUFT1/AKT pathway

(2020) Changwei Dou et al.   Cell Death & Disease

TRIM27 functions as a novel oncogene in non-triple-negative breast cancer by blocking cellular senescence through ubiquitination of p21

(2020) Li Xing et al.   Molecular Therapy-Nucleic Acids

TRIM27 acts as an oncogene and regulates cell proliferation and metastasis in non-small cell lung cancer through SIX3-β-catenin signaling

(2020) Shiyuan Liu et al.   Aging-US

MORC2 regulates C/EBPα-mediated cell differentiation via sumoylation

(2019) Jia Liu et al.   CELL DEATH AND DIFFERENTIATION

lncRNA PSTAR Promotes p53 Signaling by Inhibiting hnRNP K deSUMOylation and Suppresses Hepatocellular Carcinoma

(2019) Geng Qin et al.   HEPATOLOGY

TUFT1 Promotes Triple Negative Breast Cancer Metastasis, Stemness, and Chemoresistance by Up-Regulating the Rac1/β-Catenin Pathway

(2019) Weiguang Liu et al.   Frontiers in Oncology

TUFT1 promotes metastasis and chemoresistance in triple negative breast cancer through the TUFT1/Rab5/Rac1 pathway

(2019) Weiguang Liu et al.   Cancer Cell International

TRIM27 promotes the development of esophagus cancer via regulating PTEN/AKT signaling pathway

(2019) Liang Ma et al.   Cancer Cell International

Exosomal lncRNA HNF1A-AS1 affects cisplatin resistance in cervical cancer cells through regulating microRNA-34b/TUFT1 axis

(2019) Xiaoqiong Luo et al.   Cancer Cell International

TRIM27 functions as an oncogene by activating epithelial-mesenchymal transition and p-AKT in colorectal cancer

(2018) Yue Zhang et al.   INTERNATIONAL JOURNAL OF ONCOLOGY

A proteomic landscape of diffuse-type gastric cancer

(2018) Sai Ge et al.   Nature Communications

TUFT1 interacts with RABGAP1 and regulates mTORC1 signaling

(2018) Natsumi Kawasaki et al.   Cell Discovery

Hypoxia-induced TUFT1 promotes the growth and metastasis of hepatocellular carcinoma by activating the Ca2+/PI3K/AKT pathway

(2018) Changwei Dou et al.   ONCOGENE

TRIM27 mediates STAT3 activation at retromer-positive structures to promote colitis and colitis-associated carcinogenesis

(2018) Hong-Xia Zhang et al.   Nature Communications

A region-resolved mucosa proteome of the human stomach

(2018) Xiaotian Ni et al.   Nature Communications

TUFT1 regulates metastasis of pancreatic cancer through HIF1-Snail pathway induced epithelial–mesenchymal transition

(2016) Bin Zhou et al.   CANCER LETTERS

Abstract 1741: The association between menopause symptoms and risk of postmenopausal breast cancer among non-users of hormone therapy

(2016) Tricia Li et al.   CANCER RESEARCH

Cross-validation of survival associated biomarkers in gastric cancer using transcriptomic data of 1,065 patients

(2016) A. Marcell Szász et al.   Oncotarget

Downregulation of TRIM27 expression inhibits the proliferation of ovarian cancer cells in vitro and in vivo

(2015) Yanyan Ma et al.   LABORATORY INVESTIGATION

SENP3 regulates the global protein turnover and the Sp1 level via antagonizing SUMO2/3-targeted ubiquitination and degradation

(2015) Ming Wang et al.   Protein & Cell

De-SUMOylation of FOXC2 by SENP3 promotes the epithelial-mesenchymal transition in gastric cancer cells

(2015) Yan-hua Ren et al.   Oncotarget

Differential effect of MMSET mRNA levels on survival to first-line FOLFOX and second-line docetaxel in gastric cancer

(2014) J Wei et al.   BRITISH JOURNAL OF CANCER

Uncovering SUMOylation Dynamics during Cell-Cycle Progression Reveals FoxM1 as a Key Mitotic SUMO Target Protein

(2014) Joost Schimmel et al.   MOLECULAR CELL

Genome engineering using the CRISPR-Cas9 system

(2013) F Ann Ran et al.   Nature Protocols

Online Survival Analysis Software to Assess the Prognostic Value of Biomarkers Using Transcriptomic Data in Non-Small-Cell Lung Cancer

(2013) Balázs Győrffy et al.   PLoS One

Implementing an online tool for genome-wide validation of survival-associated biomarkers in ovarian-cancer using microarray data from 1287 patients

(2012) Balázs Győrffy et al.   ENDOCRINE-RELATED CANCER

SUMOylation and de-SUMOylation in response to DNA damage

(2011) Hong Dou et al.   FEBS LETTERS

mRNA Expression of BRCA1, PIAS1, and PIAS4 and Survival After Second-line Docetaxel in Advanced Gastric Cancer

(2011) Jia Wei et al.   JNCI-Journal of the National Cancer Institute

Ragulator-Rag Complex Targets mTORC1 to the Lysosomal Surface and Is Necessary for Its Activation by Amino Acids

(2010) Yasemin Sancak et al.   CELL

SUMO E3 ligase activity of TRIM proteins

(2010) Y Chu et al.   ONCOGENE