Is realistic neuronal modeling realistic?

Heterogeneous firing rate response of mouse layer V pyramidal neurons in the fluctuation-driven regime

(2016) Y. Zerlaut et al.   JOURNAL OF PHYSIOLOGY-LONDON

Reconstruction and Simulation of Neocortical Microcircuitry

(2015) Henry Markram et al.   CELL

Inhibitory short-term plasticity modulates neuronal activity in the rat entopeduncular nucleusin vitro

(2015) Hagar Lavian et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Brain-wide analysis of electrophysiological diversity yields novel categorization of mammalian neuron types

(2015) Shreejoy J. Tripathy et al.   JOURNAL OF NEUROPHYSIOLOGY

A Sparse Reformulation of the Green’s Function Formalism Allows Efficient Simulations of Morphological Neuron Models

(2015) Willem A. M. Wybo et al.   NEURAL COMPUTATION

ModelView for ModelDB: Online Presentation of Model Structure

(2015) Robert A. McDougal et al.   NEUROINFORMATICS

Synaptic clustering within dendrites: An emerging theory of memory formation

(2015) George Kastellakis et al.   PROGRESS IN NEUROBIOLOGY

Dendritic function in vivo

(2015) Christine Grienberger et al.   TRENDS IN NEUROSCIENCES

Anatomy and physiology of the thick-tufted layer 5 pyramidal neuron

(2015) Srikanth Ramaswamy et al.   Frontiers in Cellular Neuroscience

What Is the Most Realistic Single-Compartment Model of Spike Initiation?

(2015) Romain Brette   PLoS Computational Biology

Neuromodulation of Circuits with Variable Parameters: Single Neurons and Small Circuits Reveal Principles of State-Dependent and Robust Neuromodulation

(2014) Eve Marder et al.   Annual Review of Neuroscience

Measuring the curse of dimensionality and its effects on particle swarm optimization and differential evolution

(2014) Stephen Chen et al.   APPLIED INTELLIGENCE

A Quantitative Description of Dendritic Conductances and Its Application to Dendritic Excitation in Layer 5 Pyramidal Neurons

(2014) M. Almog et al.   JOURNAL OF NEUROSCIENCE

Many Parameter Sets in a Multicompartment Model Oscillator Are Robust to Temperature Perturbations

(2014) J. S. Caplan et al.   JOURNAL OF NEUROSCIENCE

Heteromeric Kv7.2/7.3 Channels Differentially Regulate Action Potential Initiation and Conduction in Neocortical Myelinated Axons

(2014) A. Battefeld et al.   JOURNAL OF NEUROSCIENCE

Resurgent current of voltage-gated Na+channels

(2014) Amanda H. Lewis et al.   JOURNAL OF PHYSIOLOGY-LONDON

All-optical electrophysiology in mammalian neurons using engineered microbial rhodopsins

(2014) Daniel R Hochbaum et al.   NATURE METHODS

NMDA spikes enhance action potential generation during sensory input

(2014) Lucy M Palmer et al.   NATURE NEUROSCIENCE

Axon-Carrying Dendrites Convey Privileged Synaptic Input in Hippocampal Neurons

(2014) Christian Thome et al.   NEURON

Structured Synaptic Connectivity between Hippocampal Regions

(2014) Shaul Druckmann et al.   NEURON

NMDA Receptor-Dependent Multidendrite Ca 2+ Spikes Required for Hippocampal Burst Firing In Vivo

(2014) Christine Grienberger et al.   NEURON

Patch-clamp recordings of rat neurons from acute brain slices of the somatosensory cortex during magnetic stimulation

(2014) Tamar Pashut et al.   Frontiers in Cellular Neuroscience

OpenWorm: an open-science approach to modeling Caenorhabditis elegans

(2014) Balázs Szigeti et al.   Frontiers in Computational Neuroscience

Context-aware modeling of neuronal morphologies

(2014) Benjamin Torben-Nielsen et al.   Frontiers in Neuroanatomy

Action Potential Initiation in Neocortical Inhibitory Interneurons

(2014) Tun Li et al.   PLOS BIOLOGY

Current Practice in Software Development for Computational Neuroscience and How to Improve It

(2014) Marc-Oliver Gewaltig et al.   PLoS Computational Biology

LEMS: a language for expressing complex biological models in concise and hierarchical form and its use in underpinning NeuroML 2

(2014) Robert C. Cannon et al.   Frontiers in Neuroinformatics

libNeuroML and PyLEMS: using Python to combine procedural and declarative modeling approaches in computational neuroscience

(2014) Michael Vella et al.   Frontiers in Neuroinformatics

Active Properties of Neocortical Pyramidal Neuron Dendrites

(2013) Guy Major et al.   Annual Review of Neuroscience

The use and abuse of large-scale brain models

(2013) Chris Eliasmith et al.   CURRENT OPINION IN NEUROBIOLOGY

Preserving axosomatic spiking features despite diverse dendritic morphology

(2013) Etay Hay et al.   JOURNAL OF NEUROPHYSIOLOGY

GnRH Neurons Elaborate a Long-Range Projection with Shared Axonal and Dendritic Functions

(2013) M. K. Herde et al.   JOURNAL OF NEUROSCIENCE

Dendritic spikes enhance stimulus selectivity in cortical neurons in vivo

(2013) Spencer L. Smith et al.   NATURE

Variable Dendritic Integration in Hippocampal CA3 Pyramidal Neurons

(2013) Judit K. Makara et al.   NEURON

Correlations in ion channel expression emerge from homeostatic tuning rules

(2013) T. O'Leary et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Spatial mismatch between the Na+ flux and spike initiation in axon initial segment

(2013) G. Baranauskas et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Accelerating compartmental modeling on a graphical processing unit

(2013) Roy Ben-Shalom et al.   Frontiers in Neuroinformatics

The Physiology of the Axon Initial Segment

(2012) Kevin J. Bender et al.   Annual Review of Neuroscience

Morphologic evidence for spatially clustered spines in apical dendrites of monkey neocortical pyramidal cells

(2012) Aniruddha Yadav et al.   JOURNAL OF COMPARATIVE NEUROLOGY

Automated optimization of a reduced layer 5 pyramidal cell model based on experimental data

(2012) Armin Bahl et al.   JOURNAL OF NEUROSCIENCE METHODS

Optimizing ion channel models using a parallel genetic algorithm on graphical processors

(2012) Roy Ben-Shalom et al.   JOURNAL OF NEUROSCIENCE METHODS

Inhibition of dendritic Ca2+spikes by GABABreceptors in cortical pyramidal neurons is mediated by a direct Gi/o-βγ-subunit interaction with Cav1 channels

(2012) Enrique Pérez-Garci et al.   JOURNAL OF PHYSIOLOGY-LONDON

Nonlinear dendritic processing determines angular tuning of barrel cortex neurons in vivo

(2012) Maria Lavzin et al.   NATURE

Active dendrites support efficient initiation of dendritic spikes in hippocampal CA3 pyramidal neurons

(2012) Sooyun Kim et al.   NATURE NEUROSCIENCE

Signal Processing in the Axon Initial Segment

(2012) Maarten H.P. Kole et al.   NEURON

Integration of Subthreshold and Suprathreshold Excitatory Barrages along the Somatodendritic Axis of Pyramidal Neurons

(2012) Hysell V. Oviedo et al.   PLoS One

A Large-Scale Model of the Functioning Brain

(2012) C. Eliasmith et al.   SCIENCE

The Human Brain Project

(2012) Henry Markram   SCIENTIFIC AMERICAN

Hybrid Models and Biological Model Reduction with PyDSTool

(2012) Robert Clewley   PLoS Computational Biology

Kinetic modeling of Nav1.7 provides insight into erythromelalgia-associated F1449V mutation

(2011) Meron Gurkiewicz et al.   JOURNAL OF NEUROPHYSIOLOGY

The spatio-temporal characteristics of action potential initiation in layer 5 pyramidal neurons: a voltage imaging study

(2011) Marko A. Popovic et al.   JOURNAL OF PHYSIOLOGY-LONDON

Optical recording of action potentials in mammalian neurons using a microbial rhodopsin

(2011) Joel M Kralj et al.   NATURE METHODS

Multiple models to capture the variability in biological neurons and networks

(2011) Eve Marder et al.   NATURE NEUROSCIENCE

The TREES Toolbox—Probing the Basis of Axonal and Dendritic Branching

(2011) Hermann Cuntz et al.   NEUROINFORMATICS

First Node of Ranvier Facilitates High-Frequency Burst Encoding

(2011) Maarten H.P. Kole   NEURON

Compartmentalized versus Global Synaptic Plasticity on Dendrites Controlled by Experience

(2011) Hiroshi Makino et al.   NEURON

Dendritic Spines and Distributed Circuits

(2011) Rafael Yuste   NEURON

Effective Stimuli for Constructing Reliable Neuron Models

(2011) Shaul Druckmann et al.   PLoS Computational Biology

Mechanisms of Magnetic Stimulation of Central Nervous System Neurons

(2011) Tamar Pashut et al.   PLoS Computational Biology

Models of Neocortical Layer 5b Pyramidal Cells Capturing a Wide Range of Dendritic and Perisomatic Active Properties

(2011) Etay Hay et al.   PLoS Computational Biology

Channelpedia: An Integrative and Interactive Database for Ion Channels

(2011) Rajnish Ranjan et al.   Frontiers in Neuroinformatics

The single dendritic branch as a fundamental functional unit in the nervous system

(2010) Tiago Branco et al.   CURRENT OPINION IN NEUROBIOLOGY

Ssecrett and NeuroTrace: Interactive Visualization and Analysis Tools for Large-Scale Neuroscience Data Sets

(2010) Won-Ki Jeong et al.   IEEE COMPUTER GRAPHICS AND APPLICATIONS

Fast Sodium Channel Gating Supports Localized and Efficient Axonal Action Potential Initiation

(2010) C. Schmidt-Hieber et al.   JOURNAL OF NEUROSCIENCE

Action Potentials Initiate in the Axon Initial Segment and Propagate through Axon Collaterals Reliably in Cerebellar Purkinje Neurons

(2010) A. Foust et al.   JOURNAL OF NEUROSCIENCE

RAPID REPORT: Initiation of simple and complex spikes in cerebellar Purkinje cells

(2010) Lucy M. Palmer et al.   JOURNAL OF PHYSIOLOGY-LONDON

Activity-dependent relocation of the axon initial segment fine-tunes neuronal excitability

(2010) Matthew S. Grubb et al.   NATURE

Na+ imaging reveals little difference in action potential–evoked Na+ influx between axon and soma

(2010) Ilya A Fleidervish et al.   NATURE NEUROSCIENCE

Neuronal arithmetic

(2010) R. Angus Silver   NATURE REVIEWS NEUROSCIENCE

Molecular Identity of Dendritic Voltage-Gated Sodium Channels

(2010) A. Lorincz et al.   SCIENCE

Dendritic Discrimination of Temporal Input Sequences in Cortical Neurons

(2010) T. Branco et al.   SCIENCE

Stochastic Ion Channel Gating in Dendritic Neurons: Morphology Dependence and Probabilistic Synaptic Activation of Dendritic Spikes

(2010) Robert C. Cannon et al.   PLoS Computational Biology

Impact of Dendritic Size and Dendritic Topology on Burst Firing in Pyramidal Cells

(2010) Ronald A. J. van Elburg et al.   PLoS Computational Biology

NeuroML: A Language for Describing Data Driven Models of Neurons and Networks with a High Degree of Biological Detail

(2010) Padraig Gleeson et al.   PLoS Computational Biology

One Rule to Grow Them All: A General Theory of Neuronal Branching and Its Practical Application

(2010) Hermann Cuntz et al.   PLoS Computational Biology

Automatic fitting of spiking neuron models to electrophysiological recordings

(2010) Cyrille Rossant   Frontiers in Neuroinformatics

Quantitative Assessment of the Distributions of Membrane Conductances Involved in Action Potential Backpropagation Along Basal Dendrites

(2009) Corey D. Acker et al.   JOURNAL OF NEUROPHYSIOLOGY

Cell-Type-Dependent Molecular Composition of the Axon Initial Segment

(2009) A. Lorincz et al.   JOURNAL OF NEUROSCIENCE

How Multiple Conductances Determine Electrophysiological Properties in a Multicompartment Model

(2009) A. L. Taylor et al.   JOURNAL OF NEUROSCIENCE

Divide et impera: optimizing compartmental models of neurons step by step

(2009) Arnd Roth et al.   JOURNAL OF PHYSIOLOGY-LONDON

Experimentally guided modelling of dendritic excitability in rat neocortical pyramidal neurones

(2009) Naomi Keren et al.   JOURNAL OF PHYSIOLOGY-LONDON

Distinct contributions of Nav1.6 and Nav1.2 in action potential initiation and backpropagation

(2009) Wenqin Hu et al.   NATURE NEUROSCIENCE

A configurable simulation environment for the efficient simulation of large-scale spiking neural networks on graphics processors

(2009) Jayram Moorkanikara Nageswaran et al.   NEURAL NETWORKS

Activity-Dependent Control of Neuronal Output by Local and Global Dendritic Spike Attenuation

(2009) Stefan Remy et al.   NEURON

A state-mutating genetic algorithm to design ion-channel models

(2009) V. Menon et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Synaptic Integration in Tuft Dendrites of Layer 5 Pyramidal Neurons: A New Unifying Principle

(2009) M. E. Larkum et al.   SCIENCE

Smoothing of, and Parameter Estimation from, Noisy Biophysical Recordings

(2009) Quentin J. M. Huys et al.   PLoS Computational Biology

A High-Throughput Screening Approach to Discovering Good Forms of Biologically Inspired Visual Representation

(2009) Nicolas Pinto et al.   PLoS Computational Biology

NEURON and Python

(2009) Michael Hines   Frontiers in Neuroinformatics

Evaluating automated parameter constraining procedures of neuron models by experimental and surrogate data

(2008) Shaul Druckmann et al.   BIOLOGICAL CYBERNETICS

CUDA compatible GPU cards as efficient hardware accelerators for Smith-Waterman sequence alignment

(2008) Svetlin A Manavski et al.   BMC BIOINFORMATICS

Dendrites determine the contribution of after depolarization potentials (ADPs) to generation of repetitive action potentials in hypothalamic gonadotropin releasing-hormone (GnRH) neurons

(2008) C. B. Roberts et al.   JOURNAL OF COMPUTATIONAL NEUROSCIENCE

Role of Axonal NaV1.6 Sodium Channels in Action Potential Initiation of CA1 Pyramidal Neurons

(2008) Michel Royeck et al.   JOURNAL OF NEUROPHYSIOLOGY

Learning Drives Differential Clustering of Axodendritic Contacts in the Barn Owl Auditory System

(2008) T. J. McBride et al.   JOURNAL OF NEUROSCIENCE

Compartmentalized dendritic plasticity and input feature storage in neurons

(2008) Attila Losonczy et al.   NATURE

Is action potential threshold lowest in the axon?

(2008) Maarten H P Kole et al.   NATURE NEUROSCIENCE

Action potential generation requires a high sodium channel density in the axon initial segment

(2008) Maarten H P Kole et al.   NATURE NEUROSCIENCE

Pyramidal neurons: dendritic structure and synaptic integration

(2008) Nelson Spruston   NATURE REVIEWS NEUROSCIENCE

NeuroMorpho.Org Implementation of Digital Neuroscience: Dense Coverage and Integration with the NIF

(2008) Maryam Halavi et al.   NEUROINFORMATICS

Neuronal Firing Sensitivity to Morphologic and Active Membrane Parameters

(2008) Christina M. Weaver et al.   PLoS Computational Biology

Large-scale model of mammalian thalamocortical systems

(2008) E. M. Izhikevich et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Why Are Computational Neuroscience and Systems Biology So Separate?

(2008) Erik De Schutter   PLoS Computational Biology