Action Potential Initiation in Neocortical Inhibitory Interneurons

A supercritical density of Na+ channels ensures fast signaling in GABAergic interneuron axons

(2014) Hua Hu et al.   NATURE NEUROSCIENCE

A novel de novo mutation of SCN8A (Nav1.6) with enhanced channel activation in a child with epileptic encephalopathy

(2014) Mark Estacion et al.   NEUROBIOLOGY OF DISEASE

Genetic Epilepsy Syndromes Without Structural Brain Abnormalities: Clinical Features and Experimental Models

(2014) Renzo Guerrini et al.   Neurotherapeutics

Hippocampal hyperexcitability and specific epileptiform activity in a mouse model of Dravet syndrome

(2013) Camille Liautard et al.   EPILEPSIA

Enhanced Intrinsic Excitability in Basket Cells Maintains Excitatory-Inhibitory Balance in Hippocampal Circuits

(2013) Emilie Campanac et al.   NEURON

De Novo Pathogenic SCN8A Mutation Identified by Whole-Genome Sequencing of a Family Quartet Affected by Infantile Epileptic Encephalopathy and SUDEP

(2012) Krishna R. Veeramah et al.   AMERICAN JOURNAL OF HUMAN GENETICS

De novo mutations revealed by whole-exome sequencing are strongly associated with autism

(2012) Stephan J. Sanders et al.   NATURE

Compromised function in the Nav1.2 Dravet syndrome mutation R1312T

(2012) Christoph Lossin et al.   NEUROBIOLOGY OF DISEASE

Axonal bleb recording

(2012) Wenqin Hu et al.   Neuroscience Bulletin

Palmitoylation influences the function and pharmacology of sodium channels

(2011) F. Bosmans et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Neocortical Interneurons: From Diversity, Strength

(2010) Christopher I. Moore et al.   CELL

Differences in Na+ Conductance Density and Na+ Channel Functional Properties Between Dopamine and GABA Neurons of the Rat Substantia Nigra

(2010) Vincent Seutin et al.   JOURNAL OF NEUROPHYSIOLOGY

The Roles of Somatostatin-Expressing (GIN) and Fast-Spiking Inhibitory Interneurons in up-down States of Mouse Neocortex

(2010) Erika E. Fanselow et al.   JOURNAL OF NEUROPHYSIOLOGY

Action Potentials Initiate in the Axon Initial Segment and Propagate through Axon Collaterals Reliably in Cerebellar Purkinje Neurons

(2010) A. Foust et al.   JOURNAL OF NEUROSCIENCE

RAPID REPORT: Initiation of simple and complex spikes in cerebellar Purkinje cells

(2010) Lucy M. Palmer et al.   JOURNAL OF PHYSIOLOGY-LONDON

Activity-dependent relocation of the axon initial segment fine-tunes neuronal excitability

(2010) Matthew S. Grubb et al.   NATURE

Presynaptic activity regulates Na+ channel distribution at the axon initial segment

(2010) Hiroshi Kuba et al.   NATURE

Heterozygous mutations of the voltage-gated sodium channel SCN8A are associated with spike-wave discharges and absence epilepsy in mice

(2009) Ligia A. Papale et al.   HUMAN MOLECULAR GENETICS

Cell-Type-Dependent Molecular Composition of the Axon Initial Segment

(2009) A. Lorincz et al.   JOURNAL OF NEUROSCIENCE

Axon Initial Segment Ca2+ Channels Influence Action Potential Generation and Timing

(2009) Kevin J. Bender et al.   NEURON

Dendritic Mechanisms Underlying Rapid Synaptic Activation of Fast-Spiking Hippocampal Interneurons

(2009) H. Hu et al.   SCIENCE

Impaired NaV1.2 function and reduced cell surface expression in benign familial neonatal-infantile seizures

(2008) Sunita N. Misra et al.   EPILEPSIA

Action potential generation requires a high sodium channel density in the axon initial segment

(2008) Maarten H P Kole et al.   NATURE NEUROSCIENCE

K+ Channels at the Axon Initial Segment Dampen Near-Threshold Excitability of Neocortical Fast-Spiking GABAergic Interneurons

(2008) Ethan M. Goldberg et al.   NEURON

Bergmann Glia and the Recognition Molecule CHL1 Organize GABAergic Axons and Direct Innervation of Purkinje Cell Dendrites

(2008) Fabrice Ango et al.   PLOS BIOLOGY