Neurogenic inflammation after traumatic brain injury and its potentiation of classical inflammation

Therapies negating neuroinflammation after brain trauma

(2016) Sarah Hellewell et al.   BRAIN RESEARCH

What is the evidence for the role of TRP channels in inflammatory and immune cells?

(2016) A Parenti et al.   BRITISH JOURNAL OF PHARMACOLOGY

Treatment of traumatic brain injury with anti-inflammatory drugs

(2016) Peter J. Bergold   EXPERIMENTAL NEUROLOGY

Microglia in the TBI brain: The good, the bad, and the dysregulated

(2016) David J. Loane et al.   EXPERIMENTAL NEUROLOGY

Interaction of calcitonin gene related peptide (CGRP) and substance P (SP) in human skin

(2016) Tanja Schlereth et al.   NEUROPEPTIDES

Inflammatory neuroprotection following traumatic brain injury

(2016) M. V. Russo et al.   SCIENCE

Identification of a prostaglandin D2 metabolite as a neuritogenesis enhancer targeting the TRPV1 ion channel

(2016) Takahiro Shibata et al.   Scientific Reports

Progressive inflammation-mediated neurodegeneration after traumatic brain or spinal cord injury

(2015) Alan I Faden et al.   BRITISH JOURNAL OF PHARMACOLOGY

Inflammation in acute CNS injury: a focus on the role of substance P

(2015) F Corrigan et al.   BRITISH JOURNAL OF PHARMACOLOGY

Activation of transient receptor potential vanilloid-1 (TRPV1) influences how retinal ganglion cell neurons respond to pressure-related stress

(2015) Rebecca M Sappington et al.   Channels

Microglia processes associate with diffusely injured axons following mild traumatic brain injury in the micro pig

(2015) Audrey D. Lafrenaye et al.   Journal of Neuroinflammation

Clinical evidence of inflammation driving secondary brain injury

(2015) Holly E. Hinson et al.   Journal of Trauma and Acute Care Surgery

Caveolin expression changes in the neurovascular unit after juvenile traumatic brain injury: Signs of blood–brain barrier healing?

(2015) J. Badaut et al.   NEUROSCIENCE

Inflammatory reaction after traumatic brain injury: therapeutic potential of targeting cell–cell communication by chemokines

(2015) Stefka Gyoneva et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

Clinical evidence of inflammation driving secondary brain injury

(2015) Holly E. Hinson et al.   Journal of Trauma and Acute Care Surgery

Inflammation and Neuroprotection in Traumatic Brain Injury

(2015) Kara N. Corps et al.   JAMA Neurology

Are Sensory TRP Channels Biological Alarms for Lipid Peroxidation?

(2014) Seung-In Choi et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Cannabinoids Inhibit HIV-1 Gp120-Mediated Insults in Brain Microvascular Endothelial Cells

(2014) T.-S. Lu et al.   JOURNAL OF IMMUNOLOGY

Very Early Administration of Progesterone for Acute Traumatic Brain Injury

(2014) David W. Wright et al.   NEW ENGLAND JOURNAL OF MEDICINE

A Clinical Trial of Progesterone for Severe Traumatic Brain Injury

(2014) Brett E. Skolnick et al.   NEW ENGLAND JOURNAL OF MEDICINE

The impact of microglial activation on blood-brain barrier in brain diseases

(2014) Anna Carolina Carvalho da Fonseca et al.   Frontiers in Cellular Neuroscience

Neuroinflammation and the dynamic lesion in traumatic brain injury

(2013) Erin D. Bigler   BRAIN

Microglia/Macrophage Polarization Dynamics in White Matter after Traumatic Brain Injury

(2013) Guohua Wang et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

The p38  MAPK Regulates Microglial Responsiveness to Diffuse Traumatic Brain Injury

(2013) A. D. Bachstetter et al.   JOURNAL OF NEUROSCIENCE

Role of Transient Receptor Potential Ion Channels and Evoked Levels of Neuropeptides in a Formaldehyde-Induced Model of Asthma in Balb/c Mice

(2013) Yang Wu et al.   PLoS One

Oxidative Burst of Circulating Neutrophils Following Traumatic Brain Injury in Human

(2013) Yiliu Liao et al.   PLoS One

The Role of Markers of Inflammation in Traumatic Brain Injury

(2013) Thomas Woodcock et al.   Frontiers in Neurology

Strain influences on inflammatory pathway activation, cell infiltration and complement cascade after traumatic brain injury in the rat

(2012) Faiez Al Nimer et al.   BRAIN BEHAVIOR AND IMMUNITY

A Substance P Antagonist Improves Outcome in Female Sprague Dawley Rats Following Diffuse Traumatic Brain Injury

(2012) Frances Corrigan et al.   CNS Neuroscience & Therapeutics

Further Investigations into the Speed of Cerebral Swelling Following Blunt Cranial Trauma*

(2012) Roger W. Byard et al.   JOURNAL OF FORENSIC SCIENCES

Traumatic brain injury in aged animals increases lesion size and chronically alters microglial/macrophage classical and alternative activation states

(2012) Alok Kumar et al.   NEUROBIOLOGY OF AGING

Substance P-induced changes in cell genesis following diffuse traumatic brain injury

(2012) H.L. Carthew et al.   NEUROSCIENCE

Temporal Changes in Cell Marker Expression and Cellular Infiltration in a Controlled Cortical Impact Model in Adult Male C57BL/6 Mice

(2012) Xuemei Jin et al.   PLoS One

Classical Macrophage Activation Up-Regulates Several Matrix Metalloproteinases through Mitogen Activated Protein Kinases and Nuclear Factor-κB

(2012) Wei-Chun Huang et al.   PLoS One

Caveolae, caveolins, cavins, and endothelial cell function: new insights

(2012) Grzegorz Sowa   Frontiers in Physiology

The changing phenotype of microglia from homeostasis to disease

(2012) Xiao-Guang Luo et al.   Translational Neurodegeneration

Trauma alarmins as activators of damage-induced inflammation

(2011) J. Manson et al.   BRITISH JOURNAL OF SURGERY

TRPA1 contributes to specific mechanically activated currents and sensory neuron mechanical hypersensitivity

(2011) Stuart M. Brierley et al.   JOURNAL OF PHYSIOLOGY-LONDON

Repertoire of microglial and macrophage responses after spinal cord injury

(2011) Samuel David et al.   NATURE REVIEWS NEUROSCIENCE

Cleavage of Kininogen and Subsequent Bradykinin Release by the Complement Component: Mannose-Binding Lectin-Associated Serine Protease (MASP)-1

(2011) József Dobó et al.   PLoS One

Hydrogen Sulfide and Neurogenic Inflammation in Polymicrobial Sepsis: Involvement of Substance P and ERK-NF-κB Signaling

(2011) Seah-Fang Ang et al.   PLoS One

TRPV1 antagonist, A-889425, inhibits mechanotransmission in a subclass of rat primary afferent neurons following peripheral inflammation

(2011) Jill-Desiree Brederson et al.   SYNAPSE

Blood–Brain Barrier Pathophysiology in Traumatic Brain Injury

(2011) Adam Chodobski et al.   Translational Stroke Research

Neurokinin-1 receptor: functional significance in the immune system in reference to selected infections and inflammation

(2010) Steven D. Douglas et al.   Annals of the New York Academy of Sciences

Mechanisms of cerebral edema in traumatic brain injury: therapeutic developments

(2010) James J Donkin et al.   CURRENT OPINION IN NEUROLOGY

Acetaminophen, via its reactive metabolite N-acetyl-p-benzo-quinoneimine and transient receptor potential ankyrin-1 stimulation, causes neurogenic inflammation in the airways and other tissues in rodents

(2010) Romina Nassini et al.   FASEB JOURNAL

Role of CCL2 (MCP-1) in Traumatic Brain Injury (TBI): Evidence from Severe TBI Patients and CCL2−/− Mice

(2010) Bridgette D Semple et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Trafficking of immune cells in the central nervous system

(2010) Emma H. Wilson et al.   JOURNAL OF CLINICAL INVESTIGATION

Post-Traumatic Hypoxia Exacerbates Brain Tissue Damage: Analysis of Axonal Injury and Glial Responses

(2010) Sarah C. Hellewell et al.   JOURNAL OF NEUROTRAUMA

A Substance P Antagonist Reduces Axonal Injury and Improves Neurologic Outcome When Administered Up to 12 Hours after Traumatic Brain Injury

(2010) James J. Donkin et al.   JOURNAL OF NEUROTRAUMA

TRPA1 Modulation of Spontaneous and Mechanically Evoked Firing of Spinal Neurons in Uninjured, Osteoarthritic, and Inflamed Rats

(2010) Steve McGaraughty et al.   Molecular Pain

Expression and regulation of toll-like receptors in cerebral endothelial cells

(2010) Péter Nagyőszi et al.   NEUROCHEMISTRY INTERNATIONAL

Involvement of pro- and anti-inflammatory cytokines and chemokines in the pathophysiology of traumatic brain injury

(2010) Jenna M. Ziebell et al.   Neurotherapeutics

Microglial activation and chronic neurodegeneration

(2010) Melinda E. Lull et al.   Neurotherapeutics

Albumin activates astrocytes and microglia through mitogen-activated protein kinase pathways

(2009) Hantamalala Ralay Ranaivo et al.   BRAIN RESEARCH

The Ion Channel TRPA1 Is Required for Normal Mechanosensation and Is Modulated by Algesic Stimuli

(2009) Stuart M. Brierley et al.   GASTROENTEROLOGY

The Role of Bradykinin B1 and B2 Receptors for Secondary Brain Damage after Traumatic Brain Injury in Mice

(2009) Raimund Trabold et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Substance P is Associated with the Development of Brain Edema and Functional Deficits after Traumatic Brain Injury

(2009) James J Donkin et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

TRPA1 and Cold Transduction: An Unresolved Issue?

(2009) Ombretta Caspani et al.   JOURNAL OF GENERAL PHYSIOLOGY

Differential effects of albumin on microglia and macrophages; implications for neurodegeneration following blood-brain barrier damage

(2009) Claudie Hooper et al.   JOURNAL OF NEUROCHEMISTRY

Heterogeneity of Microglial Activation in the Innate Immune Response in the Brain

(2009) Carol A. Colton   Journal of Neuroimmune Pharmacology

TRPA1 Modulates Mechanotransduction in Cutaneous Sensory Neurons

(2009) K. Y. Kwan et al.   JOURNAL OF NEUROSCIENCE

Transcriptome Profiling Reveals TGF-  Signaling Involvement in Epileptogenesis

(2009) L. P. Cacheaux et al.   JOURNAL OF NEUROSCIENCE

In Situ Detection of Inflammatory Mediators in Post Mortem Human Brain Tissue after Traumatic Injury

(2009) Tony Frugier et al.   JOURNAL OF NEUROTRAUMA

Sensing of Blood Pressure Increase by Transient Receptor Potential Vanilloid 1 Receptors on Baroreceptors

(2009) H. Sun et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

Pharmacological Blockade of TRPA1 Inhibits Mechanical Firing in Nociceptors

(2009) Patrick C Kerstein et al.   Molecular Pain

Pharmacology of Vanilloid Transient Receptor Potential Cation Channels

(2009) J. Vriens et al.   MOLECULAR PHARMACOLOGY

Expression of endothelial phosphorylated caveolin-1 is increased in brain injury

(2009) S. Nag et al.   NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY

Substance P acts via the neurokinin receptor 1 to elicit bronchoconstriction, oxidative stress, and upregulated ICAM-1 expression after oil smoke exposure

(2008) Ping-Chia Li et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Endocytic regulation of TGF-β signaling

(2008) Ye-Guang Chen   CELL RESEARCH

Moderate and severe traumatic brain injury in adults

(2008) Andrew IR Maas et al.   LANCET NEUROLOGY

TRPA1 receptor localisation in the human peripheral nervous system and functional studies in cultured human and rat sensory neurons

(2008) U. Anand et al.   NEUROSCIENCE LETTERS

Differences in the length of the carboxyl terminus mediate functional properties of neurokinin-1 receptor

(2008) J.-P. Lai et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Microglia and Astrocyte Activation by Toll-Like Receptor Ligands: Modulation by PPAR-γAgonists

(2008) Catherine Gurley et al.   PPAR Research

Transcellular transport of CCL2 across brain microvascular endothelial cells

(2007) Shujun Ge et al.   JOURNAL OF NEUROCHEMISTRY