Histone Deacetylase Inhibitors Modulate Interleukin 6-dependent CD4+T Cell Polarizationin Vitroandin Vivo

Contributions of dendritic cells and macrophages to intestinal homeostasis and immune defense

(2013) Julia Farache et al.   IMMUNOLOGY AND CELL BIOLOGY

Phase I Trial of Vorinostat Combined With Bortezomib for the Treatment of Relapsing and/or Refractory Multiple Myeloma

(2012) Donna M. Weber et al.   Clinical Lymphoma Myeloma & Leukemia

Ustekinumab Induction and Maintenance Therapy in Refractory Crohn's Disease

(2012) William J. Sandborn et al.   NEW ENGLAND JOURNAL OF MEDICINE

Safety and efficacy of an oral histone deacetylase inhibitor in systemic-onset juvenile idiopathic arthritis

(2011) Jelena Vojinovic et al.   ARTHRITIS AND RHEUMATISM

Blockade of IL-6-signaling inhibits the pathogenesis of CD4+ T cell-mediated lethal graft-versus-host reaction against minor histocompatibility antigen

(2011) Daisuke Noguchi et al.   IMMUNOLOGY LETTERS

Loss of CD4 + T Cell IL-6R Expression during Inflammation Underlines a Role for IL-6 Trans Signaling in the Local Maintenance of Th17 Cells

(2010) Gareth W. Jones et al.   JOURNAL OF IMMUNOLOGY

Clinical aspects of inflammatory bowel disease

(2009) Britta Siegmund et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Inhibition of HDAC9 Increases T Regulatory Cell Function and Prevents Colitis in Mice

(2009) Edwin F. de Zoeten et al.   GASTROENTEROLOGY

Pleiotropic anti-myeloma activity of ITF2357: inhibition of interleukin-6 receptor signaling and repression of miR-19a and miR-19b

(2009) K. Todoerti et al.   HAEMATOLOGICA

Randomized, double-blind, placebo-controlled trial of the oral interleukin-12/23 inhibitor apilimod mesylate for treatment of active Crohnʼs disease

(2009) Bruce E. Sands et al.   INFLAMMATORY BOWEL DISEASES

Human CD25highFoxp3pos regulatory T cells differentiate into IL-17-producing cells

(2008) H. J. P. M. Koenen et al.   BLOOD

RORγ-Expressing Th17 Cells Induce Murine Chronic Intestinal Inflammation via Redundant Effects of IL-17A and IL-17F

(2008) Moritz Leppkes et al.   GASTROENTEROLOGY

Histone deacetylases: novel targets for prevention of colitis-associated cancer in mice

(2008) R. Glauben et al.   GUT

Foxp3 Inhibits RORγt-mediatedIL-17AmRNA Transcription through Direct Interaction with RORγt

(2008) Kenji Ichiyama et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Blocking TH 17-polarizing cytokines by histone deacetylase inhibitors in vitro and in vivo

(2008) Daniela Bosisio et al.   JOURNAL OF LEUKOCYTE BIOLOGY

A critical function for transforming growth factor-β, interleukin 23 and proinflammatory cytokines in driving and modulating human TH-17 responses

(2008) Elisabetta Volpe et al.   NATURE IMMUNOLOGY