Reductions in the mitochondrial enzyme α-ketoglutarate dehydrogenase complex in neurodegenerative disease - beneficial or detrimental?
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Title
Reductions in the mitochondrial enzyme α-ketoglutarate dehydrogenase complex in neurodegenerative disease - beneficial or detrimental?
Authors
Keywords
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Journal
JOURNAL OF NEUROCHEMISTRY
Volume 139, Issue 5, Pages 823-838
Publisher
Wiley
Online
2016-09-01
DOI
10.1111/jnc.13836
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Note: Only part of the references are listed.- Mild mitochondrial metabolic deficits by α-ketoglutarate dehydrogenase inhibition cause prominent changes in intracellular autophagic signaling: Potential role in the pathobiology of Alzheimer's disease
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- (2016) Takeshi Onoue et al. NEUROSCIENCE LETTERS
- Induction of mitochondrial reactive oxygen species production by GSH mediated S-glutathionylation of 2-oxoglutarate dehydrogenase
- (2016) Ryan J. Mailloux et al. Redox Biology
- The 2-Oxoacid Dehydrogenase Complexes in Mitochondria Can Produce Superoxide/Hydrogen Peroxide at Much Higher Rates Than Complex I
- (2014) Casey L. Quinlan et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Neural correlates of cognitive dysfunction in Lewy body diseases and tauopathies: Combined assessment with FDG-PET and the CERAD test battery
- (2013) Sabine Hellwig et al. BRAIN AND LANGUAGE
- Tracking pathophysiological processes in Alzheimer's disease: an updated hypothetical model of dynamic biomarkers
- (2013) Clifford R Jack et al. LANCET NEUROLOGY
- Cognitive impairment in patients with Parkinson's disease: diagnosis, biomarkers, and treatment
- (2012) Per Svenningsson et al. LANCET NEUROLOGY
- Abnormal thiamine-dependent processes in Alzheimer's Disease. Lessons from diabetes
- (2012) Gary E. Gibson et al. MOLECULAR AND CELLULAR NEUROSCIENCE
- Brain metabolite alterations and cognitive dysfunction in early Huntington's disease
- (2012) Paul G. Unschuld et al. MOVEMENT DISORDERS
- Clinical and Biomarker Changes in Dominantly Inherited Alzheimer's Disease
- (2012) Randall J. Bateman et al. NEW ENGLAND JOURNAL OF MEDICINE
- Thioredoxin Reductase Deficiency Potentiates Oxidative Stress, Mitochondrial Dysfunction and Cell Death in Dopaminergic Cells
- (2012) Pamela Lopert et al. PLoS One
- Inactivation and Reactivation of the Mitochondrial α-Ketoglutarate Dehydrogenase Complex
- (2011) Qingli Shi et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Crosstalk between mitochondrial (dys)function and mitochondrial abundance
- (2011) Sébastien Michel et al. JOURNAL OF CELLULAR PHYSIOLOGY
- Important Role of Oxidative Stress Biomarkers in Huntington’s Disease
- (2011) Isaac Túnez et al. JOURNAL OF MEDICINAL CHEMISTRY
- Brain [U-13C]glucose metabolism in mice with decreased α-ketoglutarate dehydrogenase complex activity
- (2011) Linn Hege Nilsen et al. JOURNAL OF NEUROSCIENCE RESEARCH
- Deficits in the mitochondrial enzyme α-ketoglutarate dehydrogenase lead to Alzheimer's disease-like calcium dysregulation
- (2011) Gary E. Gibson et al. NEUROBIOLOGY OF AGING
- α-Ketoglutarate dehydrogenase: A mitochondrial redox sensor
- (2010) Aaron L. McLain et al. FREE RADICAL RESEARCH
- Respiration-dependent H2O2Removal in Brain Mitochondria via the Thioredoxin/Peroxiredoxin System
- (2010) Derek A. Drechsel et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Cognition, glucose metabolism and amyloid burden in Alzheimer's disease
- (2010) Ansgar J. Furst et al. NEUROBIOLOGY OF AGING
- Synthetic regulators of the 2-oxoglutarate oxidative decarboxylation alleviate the glutamate excitotoxicity in cerebellar granule neurons
- (2009) Maria S. Kabysheva et al. BIOCHEMICAL PHARMACOLOGY
- Mitochondrial dihydrolipoyl succinyltransferase deficiency accelerates amyloid pathology and memory deficit in a transgenic mouse model of amyloid deposition
- (2009) Magali Dumont et al. FREE RADICAL BIOLOGY AND MEDICINE
- Mild reduction in the activity of the α-ketoglutarate dehydrogenase complex elevates GABA shunt and glycolysis
- (2009) Qingli Shi et al. JOURNAL OF NEUROCHEMISTRY
- Mice deficient in dihydrolipoyl succinyl transferase show increased vulnerability to mitochondrial toxins
- (2009) Lichuan Yang et al. NEUROBIOLOGY OF DISEASE
- Novel functions of the α-ketoglutarate dehydrogenase complex may mediate diverse oxidant-induced changes in mitochondrial enzymes associated with Alzheimer's disease
- (2008) Qingli Shi et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE
- Novel isoenzyme of 2-oxoglutarate dehydrogenase is identified in brain, but not in heart
- (2008) Victoria Bunik et al. FEBS Journal
- Influence of mitochondrial enzyme deficiency on adult neurogenesis in mouse models of neurodegenerative diseases
- (2008) N.Y. Calingasan et al. NEUROSCIENCE
- Reversible Inhibition of α-Ketoglutarate Dehydrogenase by Hydrogen Peroxide: Glutathionylation and Protection of Lipoic Acid†
- (2007) Milana A. B. Applegate et al. BIOCHEMISTRY
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