Astrocytic and microglial nicotinic acetylcholine receptors: an overlooked issue in Alzheimer’s disease

Picomolar Amyloid-β Peptides Enhance Spontaneous Astrocyte Calcium Transients

(2018) Linda Lee et al.   JOURNAL OF ALZHEIMERS DISEASE

Glial Cell-Line Derived Neurotrophic Factor (GDNF) Concentrations in Cerebrospinal Fluid and Serum of Patients with Early Alzheimer's Disease and Normal Controls

(2017) Guido Straten et al.   JOURNAL OF ALZHEIMERS DISEASE

Neuroinflammation in Alzheimer's Disease: Mechanisms, Pathologic Consequences, and Potential for Therapeutic Manipulation

(2017) Kenneth Hensley   JOURNAL OF ALZHEIMERS DISEASE

Regulation of nicotinic acetylcholine receptors in Alzheimer׳s disease: A possible role of chaperones

(2015) Saeed Sadigh-Eteghad et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Activation of α7 nicotinic acetylcholine receptors protects astrocytes against oxidative stress-induced apoptosis: Implications for Parkinson's disease

(2015) Yuan Liu et al.   NEUROPHARMACOLOGY

Selective activation of α7 nicotinic acetylcholine receptor by PHA-543613 improves Aβ25–35-mediated cognitive deficits in mice

(2015) S. Sadigh-Eteghad et al.   NEUROSCIENCE

Glia in the pathogenesis of neurodegenerative diseases

(2014) Alexei Verkhratsky et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

A nicotinic receptor-mediated anti-inflammatory effect of the flavonoid rhamnetin in BV2 microglia

(2014) Joseph A. Lutz et al.   FITOTERAPIA

α7 Nicotinic acetylcholine receptor-specific antibody stimulates interleukin-6 production in human astrocytes through p38-dependent pathway

(2014) Olena Kalashnyk et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Deficiency of GDNF Receptor GFR 1 in Alzheimer's Neurons Results in Neuronal Death

(2014) Y. Konishi et al.   JOURNAL OF NEUROSCIENCE

Amyloid-Beta: A Crucial Factor in Alzheimer's Disease

(2014) Saeed Sadigh-Eteghad et al.   MEDICAL PRINCIPLES AND PRACTICE

Nicotine Inhibits Microglial Proliferation and Is Neuroprotective in Global Ischemia Rats

(2014) Yan-Zhong Guan et al.   MOLECULAR NEUROBIOLOGY

GABA from reactive astrocytes impairs memory in mouse models of Alzheimer's disease

(2014) Seonmi Jo et al.   NATURE MEDICINE

Central Nervous System Regenerative Failure: Role of Oligodendrocytes, Astrocytes, and Microglia

(2014) Jerry Silver et al.   Cold Spring Harbor Perspectives in Biology

Optogenetic astrocyte activation modulates response selectivity of visual cortex neurons in vivo

(2014) Gertrudis Perea et al.   Nature Communications

Apolipoprotein E, amyloid-beta, and neuroinflammation in Alzheimer’s disease

(2014) Evan Dorey et al.   Neuroscience Bulletin

Perinatal Hypoxia-Ischemia Reducesα7 Nicotinic Receptor Expression and Selectiveα7 Nicotinic Receptor Stimulation Suppresses Inflammation and Promotes Microglial Mox Phenotype

(2014) Sansan Hua et al.   Biomed Research International

The Microglial α7-Acetylcholine Nicotinic Receptor Is a Key Element in Promoting Neuroprotection by Inducing Heme Oxygenase-1 via Nuclear Factor Erythroid-2-Related Factor 2

(2013) Esther Parada et al.   ANTIOXIDANTS & REDOX SIGNALING

Microglial calcium signaling in the adult, aged and diseased brain

(2013) Bianca Brawek et al.   CELL CALCIUM

On the Interaction of β-Amyloid Peptides and α7-Nicotinic Acetylcholine Receptors in Alzheimer’s Disease

(2013) Murat Oz et al.   Current Alzheimer Research

Astrocyte-Neuron Interaction at Tripartite Synapses

(2013) Alberto Pérez-Alvarez et al.   CURRENT DRUG TARGETS

Antioxidant Activity of Galantamine and Some of its Derivatives

(2013) D. Tsvetkova et al.   CURRENT MEDICINAL CHEMISTRY

Neurotransmitters and Microglial-Mediated Neuroinflammation

(2013) Moonhee Lee   CURRENT PROTEIN & PEPTIDE SCIENCE

Kynurenic acid, by targeting α7 nicotinic acetylcholine receptors, modulates extracellular GABA levels in the rat striatumin vivo

(2013) Sarah Beggiato et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Acetylcholine and antibodies against the acetylcholine receptor protect neurons and astrocytes against beta-amyloid toxicity

(2013) Anna V. Kamynina et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Activation of α7-containing nicotinic receptors on astrocytes triggers AMPA receptor recruitment to glutamatergic synapses

(2013) Xulong Wang et al.   JOURNAL OF NEUROCHEMISTRY

Upregulation of astrocytic α7 nicotinic receptors in Alzheimer's disease brain- possible relevant to amyloid pathology

(2013) Wenfeng Yu et al.   Molecular Neurodegeneration

Neuroscience: Map the other brain

(2013) R. Douglas Fields   NATURE

Primary cultures of rat cortical microglia treated with nicotine increases in the expression of excitatory amino acid transporter 1 (GLAST) via the activation of the α7 nicotinic acetylcholine receptor

(2013) N. Morioka et al.   NEUROSCIENCE

Neuregulin Upregulates Microglial α7 Nicotinic Acetylcholine Receptor Expression in Immortalized Cell Lines: Implications for Regulating Neuroinflammation

(2013) Malwina Mencel et al.   PLoS One

α7 Nicotinic Receptor-Mediated Astrocytic Gliotransmitter Release: Aβ Effects in a Preclinical Alzheimer’s Mouse Model

(2013) Tiina Maria Pirttimaki et al.   PLoS One

Neuroglia at the Crossroads of Homoeostasis, Metabolism and Signalling: Evolution of the Concept

(2012) Vladimir Parpura et al.   ASN Neuro

Neuroinflammation, Oxidative Stress and the Pathogenesis of Alzheimers Disease

(2012) Paula Agostinho et al.   CURRENT PHARMACEUTICAL DESIGN

Melatonin attenuated mediators of neuroinflammation and alpha-7 nicotinic acetylcholine receptor mRNA expression in lipopolysaccharide (LPS) stimulated rat astrocytoma cells, C6

(2012) Rituraj Niranjan et al.   FREE RADICAL RESEARCH

Glial cells in (patho)physiology

(2012) Vladimir Parpura et al.   JOURNAL OF NEUROCHEMISTRY

Glutamatergic Synapse Formation is Promoted by  7-Containing Nicotinic Acetylcholine Receptors

(2012) A. F. Lozada et al.   JOURNAL OF NEUROSCIENCE

Cholinergic Coordination of Presynaptic and Postsynaptic Activity Induces Timing-Dependent Hippocampal Synaptic Plasticity

(2012) Z. Gu et al.   JOURNAL OF NEUROSCIENCE

Possible neuroprotective property of nicotinic acetylcholine receptors in association with predominant upregulation of glial cell line-derived neurotrophic factor in astrocytes

(2012) Takeshi Takarada et al.   JOURNAL OF NEUROSCIENCE RESEARCH

Astrocyte-derived GDNF is a potent inhibitor of microglial activation

(2012) Sandra Moreira Rocha et al.   NEUROBIOLOGY OF DISEASE

Nicotinic ACh Receptors in the Hippocampus: Role in Excitability and Plasticity

(2012) J. L. Yakel   NICOTINE & TOBACCO RESEARCH

Astrocytes Mediate In Vivo Cholinergic-Induced Synaptic Plasticity

(2012) Marta Navarrete et al.   PLOS BIOLOGY

Research update: Alpha7 nicotinic acetylcholine receptor mechanisms in Alzheimer's disease

(2011) H. Rheinallt Parri et al.   BIOCHEMICAL PHARMACOLOGY

Chaperoning α7 neuronal nicotinic acetylcholine receptors

(2011) Ana S. Vallés et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Transmitter- and hormone-activated Ca2+ responses in adult microglia/brain macrophages in situ recorded after viral transduction of a recombinant Ca2+ sensor

(2011) Stefanie Seifert et al.   CELL CALCIUM

Amyloid β peptide oligomers directly activate NMDA receptors

(2011) Laura Texidó et al.   CELL CALCIUM

Mihály (Michael von) Lenhossék (1863–1937)

(2011) Frank W. Stahnisch et al.   JOURNAL OF NEUROLOGY

Soluble A  Oligomers Inhibit Long-Term Potentiation through a Mechanism Involving Excessive Activation of Extrasynaptic NR2B-Containing NMDA Receptors

(2011) S. Li et al.   JOURNAL OF NEUROSCIENCE

Timing-Dependent Septal Cholinergic Induction of Dynamic Hippocampal Synaptic Plasticity

(2011) Zhenglin Gu et al.   NEURON

Physiology of Microglia

(2011) Helmut Kettenmann et al.   PHYSIOLOGICAL REVIEWS

Kynurenine and its metabolites in Alzheimer's disease patients

(2010) E Gulaj et al.   Advances in Medical Sciences

Abeta-mediated glutamate release from astrocytes

(2010) Sara Sanz-Blasco et al.   Alzheimers & Dementia

Mechanisms of Cell Protection by Heme Oxygenase-1

(2010) Raffaella Gozzelino et al.   Annual Review of Pharmacology and Toxicology

Inositol 1,4,5-trisphosphate signaling maintains the activity of glutamate uptake in Bergmann glia

(2010) Masato Mashimo et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Galantamine-induced Amyloid-β Clearance Mediated via Stimulation of Microglial Nicotinic Acetylcholine Receptors

(2010) Kazuyuki Takata et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Amyloid-β–induced neuronal dysfunction in Alzheimer's disease: from synapses toward neural networks

(2010) Jorge J Palop et al.   NATURE NEUROSCIENCE

Astrocytes: biology and pathology

(2009) Michael V. Sofroniew et al.   ACTA NEUROPATHOLOGICA

Nicotinic mechanisms influencing synaptic plasticity in the hippocampus

(2009) Andon Nicholas Placzek et al.   ACTA PHARMACOLOGICA SINICA

Cellular trafficking of nicotinic acetylcholine receptors

(2009) Paul A St john   ACTA PHARMACOLOGICA SINICA

Activation of microglia by neuronal activity: Results from a new in vitro paradigm based on neuronal-silicon interfacing technology

(2009) Johanna Hung et al.   BRAIN BEHAVIOR AND IMMUNITY

The BTB-MATH protein BATH-42 interacts with RIC-3 to regulate maturation of nicotinic acetylcholine receptors

(2009) A. Shteingauz et al.   JOURNAL OF CELL SCIENCE

Picomolar Amyloid-  Positively Modulates Synaptic Plasticity and Memory in Hippocampus

(2009) D. Puzzo et al.   JOURNAL OF NEUROSCIENCE

Neuroscience: Glia — more than just brain glue

(2009) Nicola J. Allen et al.   NATURE

Astrocyte-Mediated Distributed Plasticity at Hypothalamic Glutamate Synapses

(2009) Grant R.J. Gordon et al.   NEURON

Activation of nicotinic acetylcholine receptor prevents the production of reactive oxygen species in fibrillar β amyloid peptide (1-42)-stimulated microglia

(2008) Ju Hyun Moon et al.   EXPERIMENTAL AND MOLECULAR MEDICINE

Anti-inflammatory effects of prostaglandin E2 in the central nervous system in response to brain injury and circulating lipopolysaccharide

(2003) Ji Zhang et al.   JOURNAL OF NEUROCHEMISTRY