Arteriovenous malformations in hereditary haemorrhagic telangiectasia: looking beyond ALK1-NOTCH interactions

Context-specific interactions between Notch and ALK1 cannot explain ALK1-associated arteriovenous malformations

(2015) Elizabeth R. Rochon et al.   CARDIOVASCULAR RESEARCH

Tmem100 Is a Regulator of TRPA1-TRPV1 Complex and Contributes to Persistent Pain

(2015) Hao-Jui Weng et al.   NEURON

Essential role for TMEM100 in vascular integrity but limited contributions to the pathogenesis of hereditary haemorrhagic telangiectasia

(2014) Eun-Hye Moon et al.   CARDIOVASCULAR RESEARCH

Molecular identification of venous progenitors in the dorsal aorta reveals an aortic origin for the cardinal vein in mammals

(2014) H. Lindskog et al.   DEVELOPMENT

Deletion of Rbpj from postnatal endothelium leads to abnormal arteriovenous shunting in mice

(2014) C. M. Nielsen et al.   DEVELOPMENT

Impairment of endothelial-mesenchymal transformation during atrioventricular cushion formation inTmem100null embryos

(2014) Ken Mizuta et al.   DEVELOPMENTAL DYNAMICS

Endothelial Depletion of Acvrl1 in Mice Leads to Arteriovenous Malformations Associated with Reduced Endoglin Expression

(2014) Simon Tual-Chalot et al.   PLoS One

Constitutively active Notch4 receptor elicits brain arteriovenous malformations through enlargement of capillary-like vessels

(2014) Patrick A. Murphy et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The role of BMPs in endothelial cell function and dysfunction

(2014) Laura A. Dyer et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Endothelial signaling and the molecular basis of arteriovenous malformation

(2013) Deepak Atri et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

The use of US health insurance data for surveillance of rare disorders: hereditary hemorrhagic telangiectasia

(2013) Scott D. Grosse et al.   GENETICS IN MEDICINE

Notch4 is activated in endothelial and smooth muscle cells in human brain arteriovenous malformations

(2013) Qichuan ZhuGe et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Hes1 and Hes5 regulate vascular remodeling and arterial specification of endothelial cells in brain vascular development

(2013) Masashi Kitagawa et al.   MECHANISMS OF DEVELOPMENT

Context-dependent signaling defines roles of BMP9 and BMP10 in embryonic and postnatal development

(2013) H. Chen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Stalk Cell Phenotype Depends on Integration of Notch and Smad1/5 Signaling Cascades

(2012) Iván M. Moya et al.   DEVELOPMENTAL CELL

ALK1 Signaling Inhibits Angiogenesis by Cooperating with the Notch Pathway

(2012) Bruno Larrivée et al.   DEVELOPMENTAL CELL

Endoglin Requirement for BMP9 Signaling in Endothelial Cells Reveals New Mechanism of Action for Selective Anti-Endoglin Antibodies

(2012) Olivier Nolan-Stevaux et al.   PLoS One

Force-specific activation of Smad1/5 regulates vascular endothelial cell cycle progression in response to disturbed flow

(2012) J. Zhou et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Tmem100, an ALK1 receptor signaling-dependent gene essential for arterial endothelium differentiation and vascular morphogenesis

(2012) Satoshi Somekawa et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Notch4 Normalization Reduces Blood Vessel Size in Arteriovenous Malformations

(2012) P. A. Murphy et al.   Science Translational Medicine

RhoA-Mediated Signaling in Notch-Induced Senescence-Like Growth Arrest and Endothelial Barrier Dysfunction

(2011) Deepak Venkatesh et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Interaction between alk1 and blood flow in the development of arteriovenous malformations

(2011) P. Corti et al.   DEVELOPMENT

ChIP-seq reveals cell type-specific binding patterns of BMP-specific Smads and a novel binding motif

(2011) Masato Morikawa et al.   NUCLEIC ACIDS RESEARCH

ALK1 heterozygosity delays development of late normal tissue damage in the irradiated mouse kidney

(2011) Marion Scharpfenecker et al.   RADIOTHERAPY AND ONCOLOGY

Feed-forward Signaling by Membrane-bound Ligand Receptor Circuit

(2010) Vincenza Caolo et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Constitutively active endothelial Notch4 causes lung arteriovenous shunts in mice

(2009) Doug Miniati et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Notch-1 signalling is activated in brain arteriovenous malformations in humans

(2009) Q. ZhuGe et al.   BRAIN

Endothelium-Dependent Cerebral Artery Dilation Mediated by TRPA1 and Ca 2+ -Activated K + Channels

(2009) Scott Earley et al.   CIRCULATION RESEARCH

Hereditary haemorrhagic telangiectasia: a clinical and scientific review

(2009) Fatima S Govani et al.   EUROPEAN JOURNAL OF HUMAN GENETICS

The pulmonary vascular complications of hereditary haemorrhagic telangiectasia

(2009) M. E. Faughnan et al.   EUROPEAN RESPIRATORY JOURNAL

Real-time imaging of de novo arteriovenous malformation in a mouse model of hereditary hemorrhagic telangiectasia

(2009) Sung Ok Park et al.   JOURNAL OF CLINICAL INVESTIGATION

Endothelial Notch signaling is upregulated in human brain arteriovenous malformations and a mouse model of the disease

(2009) Patrick A Murphy et al.   LABORATORY INVESTIGATION

Selective Use of ADAM10 and ADAM17 in Activation of Notch1 Signaling

(2009) E. C. Bozkulak et al.   MOLECULAR AND CELLULAR BIOLOGY

Overexpression of delta-like 4 induces arterialization and attenuates vessel formation in developing mouse embryos

(2008) A. Trindade et al.   BLOOD

Bone Morphogenetic Protein-9 Is a Circulating Vascular Quiescence Factor

(2008) Laurent David et al.   CIRCULATION RESEARCH

Artery and vein size is balanced by Notch and ephrin B2/EphB4 during angiogenesis

(2008) Y. H. Kim et al.   DEVELOPMENT

Trpv4 induces collateral vessel growth during regeneration of the arterial circulation

(2008) Christian Troidl et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Foxc Transcription Factors Directly Regulate Dll4 and Hey2 Expression by Interacting with the VEGF-Notch Signaling Pathways in Endothelial Cells

(2008) Hisaki Hayashi et al.   PLoS One

Endothelial Notch4 signaling induces hallmarks of brain arteriovenous malformations in mice

(2008) P. A. Murphy et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

ALK5- and TGFBR2-independent role of ALK1 in the pathogenesis of hereditary hemorrhagic telangiectasia type 2

(2007) S. O. Park et al.   BLOOD