Resveratrol inhibits renal interstitial fibrosis in diabetic nephropathy by regulating AMPK/NOX4/ROS pathway

AMP-Activated Protein Kinase Alleviates Extracellular Matrix Accumulation in High Glucose-Induced Renal Fibroblasts through mTOR Signaling Pathway

(2015) Xia Luo et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

Nox and renal disease

(2015) Chet E. Holterman et al.   CLINICAL SCIENCE

Resveratrol prevents high glucose-induced epithelial–mesenchymal transition in renal tubular epithelial cells by inhibiting NADPH oxidase/ROS/ERK pathway

(2015) Ting He et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Increase in AMPK brought about by cocoa is renoprotective in experimental diabetes mellitus by reducing NOX4/TGFβ-1 signaling

(2014) Alexandros Papadimitriou et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

Klotho suppresses renal tubulo-interstitial fibrosis by controlling basic fibroblast growth factor-2 signalling

(2014) Xu Guan et al.   JOURNAL OF PATHOLOGY

Mammalian Target of Rapamycin Regulates Nox4-Mediated Podocyte Depletion in Diabetic Renal Injury

(2013) Assaad A. Eid et al.   DIABETES

AMPK dysregulation promotes diabetes-related reduction of superoxide and mitochondrial function

(2013) Laura L. Dugan et al.   JOURNAL OF CLINICAL INVESTIGATION

NADPH Oxidases, Reactive Oxygen Species, and the Kidney: Friend and Foe

(2013) M. Sedeek et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Origin and function of myofibroblasts in kidney fibrosis

(2013) Valerie S LeBleu et al.   NATURE MEDICINE

Resveratrol as a therapeutic agent for renal fibrosis induced by unilateral ureteral obstruction

(2013) Jin Liang et al.   RENAL FAILURE

Glucose-Independent Glutamine Metabolism via TCA Cycling for Proliferation and Survival in B Cells

(2012) Anne Le et al.   Cell Metabolism

Resveratrol prevents renal lipotoxicity and inhibits mesangial cell glucotoxicity in a manner dependent on the AMPK–SIRT1–PGC1α axis in db/db mice

(2012) M. Y. Kim et al.   DIABETOLOGIA

α1AMP-Activated Protein Kinase Preserves Endothelial Function During Chronic Angiotensin II Treatment by Limiting Nox2 Upregulation

(2011) Swenja Schuhmacher et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Resveratrol protects diabetic kidney by attenuating hyperglycemia-mediated oxidative stress and renal inflammatory cytokines via Nrf2–Keap1 signaling

(2011) P. Palsamy et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Resveratrol Improves Oxidative Stress and Protects Against Diabetic Nephropathy Through Normalization of Mn-SOD Dysfunction in AMPK/SIRT1-Independent Pathway

(2011) M. Kitada et al.   DIABETES

Dysfunction of fibroblasts of extrarenal origin underlies renal fibrosis and renal anemia in mice

(2011) Nariaki Asada et al.   JOURNAL OF CLINICAL INVESTIGATION

Cellular and molecular mechanisms of renal fibrosis

(2011) Youhua Liu   Nature Reviews Nephrology

Rescue of mesangial cells from high glucose-induced over-proliferation and extracellular matrix secretion by hydrogen sulfide

(2011) P. Yuan et al.   NEPHROLOGY DIALYSIS TRANSPLANTATION

Resveratrol Attenuates Renal Hypertrophy in Early-Stage Diabetes by Activating AMPK

(2010) Da-Fa Ding et al.   AMERICAN JOURNAL OF NEPHROLOGY

NOX2 Complex–Derived ROS as Immune Regulators

(2010) Outi Sareila et al.   ANTIOXIDANTS & REDOX SIGNALING

Use of Cells Expressing γ Subunit Variants to Identify Diverse Mechanisms of AMPK Activation

(2010) Simon A. Hawley et al.   Cell Metabolism

AMP-activated Protein Kinase (AMPK) Negatively Regulates Nox4-dependent Activation of p53 and Epithelial Cell Apoptosis in Diabetes

(2010) Assaad A. Eid et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

NAD(P)H Oxidase Mediates TGF- 1-Induced Activation of Kidney Myofibroblasts

(2009) C. D. Bondi et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

AMP-activated kinase may suppress NADPH oxidase activation in vascular tissues

(2009) Mark F. McCarty et al.   MEDICAL HYPOTHESES

NADPH oxidase-4 mediates myofibroblast activation and fibrogenic responses to lung injury

(2009) Louise Hecker et al.   NATURE MEDICINE

Fibroblast activation and myofibroblast generation in obstructive nephropathy

(2009) María T. Grande et al.   Nature Reviews Nephrology

Origin of renal myofibroblasts in the model of unilateral ureter obstruction in the rat

(2008) Nicolas Picard et al.   HISTOCHEMISTRY AND CELL BIOLOGY