Trehalose and tardigrade CAHS proteins work synergistically to promote desiccation tolerance

Production of reactive oxygen species and involvement of bioprotectants during anhydrobiosis in the tardigrade Paramacrobiotus spatialis

(2022) Ilaria Giovannini et al.   Scientific Reports

Parallel evolution of trehalose production machinery in anhydrobiotic animals via recurrent gene loss and horizontal transfer

(2021) Yuichiro Hara et al.   Open Biology

The Tardigrade Damage Suppressor Protein Modulates Transcription Factor and DNA Repair Genes in Human Cells Treated with Hydroxyl Radicals and UV-C

(2021) Claudia Ricci et al.   Biology-Basel

Combined metabolome and transcriptome analysis reveals key components of complete desiccation tolerance in an anhydrobiotic insect

(2020) Alina Ryabova et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Revealing the Hidden Sensitivity of Intrinsically Disordered Proteins to their Chemical Environment

(2020) David Moses et al.   Journal of Physical Chemistry Letters

Protecting activity of desiccated enzymes

(2019) Samantha Piszkiewicz et al.   PROTEIN SCIENCE

Metabolomics reveals novel insight on dormancy of aquatic invertebrate encysted embryos

(2019) Evelien Rozema et al.   Scientific Reports

Comparative transcriptomics suggest unique molecular adaptations within tardigrade lineages

(2019) Maria Kamilari et al.   BMC GENOMICS

Mechanisms and evolution of resistance to environmental extremes in animals

(2019) Thomas C. Boothby   EvoDevo

Synergy between the small intrinsically disordered protein Hsp12 and trehalose sustain viability after severe desiccation

(2018) Skylar Xantus Kim et al.   eLife

Tardigrades Use Intrinsically Disordered Proteins to Survive Desiccation

(2017) Thomas C. Boothby et al.   MOLECULAR CELL

Extremotolerant tardigrade genome and improved radiotolerance of human cultured cells by tardigrade-unique protein

(2016) Takuma Hashimoto et al.   Nature Communications

Genome sequencing of a single tardigrade Hypsibius dujardini individual

(2016) Kazuharu Arakawa et al.   Scientific Data

Evidence for extensive horizontal gene transfer from the draft genome of a tardigrade

(2015) Thomas C. Boothby et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Increasing intracellular trehalose is sufficient to confer desiccation tolerance toSaccharomyces cerevisiae

(2015) Hugo Tapia et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Classification of Intrinsically Disordered Regions and Proteins

(2014) Robin van der Lee et al.   CHEMICAL REVIEWS

Trehalose Is a Versatile and Long-Lived Chaperone for Desiccation Tolerance

(2014) Hugo Tapia et al.   CURRENT BIOLOGY

Anhydrobiosis: an unsolved problem

(2014) JOHN H. CROWE   PLANT CELL AND ENVIRONMENT

Towards Decrypting Cryptobiosis—Analyzing Anhydrobiosis in the Tardigrade Milnesium tardigradum Using Transcriptome Sequencing

(2014) Chong Wang et al.   PLoS One

Single-molecule spectroscopy reveals polymer effects of disordered proteins in crowded environments

(2014) Andrea Soranno et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Analysis of DNA Repair and Protection in the Tardigrade Ramazzottius varieornatus and Hypsibius dujardini after Exposure to UVC Radiation

(2013) Daiki D. Horikawa et al.   PLoS One

Describing sequence–ensemble relationships for intrinsically disordered proteins

(2012) Albert H. Mao et al.   BIOCHEMICAL JOURNAL

Identification of the trehalose-6-phosphate synthase (tps) gene in desiccation tolerant and intolerant tardigrades

(2012) Michele Cesari et al.   ITALIAN JOURNAL OF ZOOLOGY

Trehalose Renders the Dauer Larva of Caenorhabditis elegans Resistant to Extreme Desiccation

(2011) Cihan Erkut et al.   CURRENT BIOLOGY

Transcriptome survey of the anhydrobiotic tardigrade Milnesium tardigradum in comparison with Hypsibius dujardini and Richtersius coronifer

(2010) Brahim Mali et al.   BMC GENOMICS

Antioxidant defences in hydrated and desiccated states of the tardigrade Paramacrobiotus richtersi

(2010) Angela M. Rizzo et al.   COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY B-BIOCHEMISTRY & MOLECULAR BIOLOGY