A seven-transmembrane protein-TM7SF3, resides in nuclear speckles and regulates alternative splicing

Limited Proteolysis-Coupled Mass Spectrometry Identifies Phosphatidylinositol 4,5-Bisphosphate Effectors in Human Nuclear Proteome

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The F-Actin-Binding MPRIP Forms Phase-Separated Condensates and Associates with PI(4,5)P2 and Active RNA Polymerase II in the Cell Nucleus

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Highly accurate protein structure prediction with AlphaFold

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The Alazami Syndrome-Associated Protein LARP7 Guides U6 Small Nuclear RNA Modification and Contributes to Splicing Robustness

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Cis- and trans-regulations of pre-mRNA splicing by RNA editing enzymes influence cancer development

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Impact of GPCR Structures on Drug Discovery

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Super-Resolution Localisation of Nuclear PI(4)P and Identification of Its Interacting Proteome

(2020) Veronika Fáberová et al.   Cells

Identification and validation of critical alternative splicing events and splicing factors in gastric cancer progression

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The Sub-Nuclear Localization of RNA-Binding Proteins in KSHV-Infected Cells

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QKI-5 regulates the alternative splicing of cytoskeletal gene ADD3 in lung cancer

(2020) Jin-Zhu Wang et al.   Journal of Molecular Cell Biology

Molecular anatomy of the architectural NEAT1 noncoding RNA: The domains, interactors, and biogenesis pathway required to build phase‐separated nuclear paraspeckles

(2019) Tetsuro Hirose et al.   Wiley Interdisciplinary Reviews-RNA

Nuclear Phosphoinositides—Versatile Regulators of Genome Functions

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Availability of splicing factors in the nucleoplasm can regulate the release of mRNA from the gene after transcription

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Nuclear phosphatidylinositol 4,5-bisphosphate islets contribute to efficient RNA polymerase II-dependent transcription

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Role of Lamin A/C Gene Mutations in the Signaling Defects Leading to Cardiomyopathies

(2018) Andrea Gerbino et al.   Frontiers in Physiology

Cytoplasmic poly(A)-binding protein 1 (PABPC1) interacts with the RNA-binding protein hnRNPLL and thereby regulates immunoglobulin secretion in plasma cells

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Multilayered Control of Alternative Splicing Regulatory Networks by Transcription Factors

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Alternative splicing as a regulator of development and tissue identity

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A novel role of fragile X mental retardation protein in pre-mRNA alternative splicing through RNA-binding protein 14

(2017) Lin-Tao Zhou et al.   NEUROSCIENCE

MRPL33 and its splicing regulator hnRNPK are required for mitochondria function and implicated in tumor progression

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Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing

(2017) Teng Fei et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Connecting the dots: chromatin and alternative splicing in EMT

(2016) Jessica A. Warns et al.   Biochemistry and Cell Biology

Alternative splicing and cell survival: from tissue homeostasis to disease

(2016) Maria Paola Paronetto et al.   CELL DEATH AND DIFFERENTIATION

TM7SF3, a novel p53-regulated homeostatic factor, attenuates cellular stress and the subsequent induction of the unfolded protein response

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GeneAnalytics: An Integrative Gene Set Analysis Tool for Next Generation Sequencing, RNAseq and Microarray Data

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ATtRACT—a database of RNA-binding proteins and associated motifs

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A new view of transcriptome complexity and regulation through the lens of local splicing variations

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Regulation of Alternative Splicing Through Coupling with Transcription and Chromatin Structure

(2015) Shiran Naftelberg et al.   Annual Review of Biochemistry

MECHANISMS IN ENDOCRINOLOGY: Alternative splicing: the new frontier in diabetes research

(2015) Jonàs Juan-Mateu et al.   EUROPEAN JOURNAL OF ENDOCRINOLOGY

G Protein–Coupled Receptor Signaling in Cardiac Nuclear Membranes

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Prion-like domains in RNA binding proteins are essential for building subnuclear paraspeckles

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hnRNP U protein is required for normal pre-mRNA splicing and postnatal heart development and function

(2015) Junqiang Ye et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Oncogenic fusion protein EWS-FLI1 is a network hub that regulates alternative splicing

(2015) Saravana P. Selvanathan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The alternative role of DNA methylation in splicing regulation

(2015) Galit Lev Maor et al.   TRENDS IN GENETICS

The IRE1α/XBP1s Pathway Is Essential for the Glucose Response and Protection of β Cells

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Segmentation and quantification of subcellular structures in fluorescence microscopy images using Squassh

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STRING v10: protein–protein interaction networks, integrated over the tree of life

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Linking Spermatid Ribonucleic Acid (RNA) Binding Protein and Retrogene Diversity to Reproductive Success

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SUMOylation of hnRNP-K is required for p53-mediated cell-cycle arrest in response to DNA damage

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p53 antagonizes the unfolded protein response and inhibits ground glass hepatocyte development during endoplasmic reticulum stress

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Tumor suppressor RBM5 directly interacts with the DExD/H-box protein DHX15 and stimulates its helicase activity

(2012) Zhaoyang Niu et al.   FEBS LETTERS

Selective Serotonin Reuptake Inhibitors (SSRIs) Inhibit Insulin Secretion and Action in Pancreatic β Cells

(2012) Roi Isaac et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Ddx18 is essential for cell-cycle progression in zebrafish hematopoietic cells and is mutated in human AML

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An siRNA screen identifies transmembrane 7 superfamily member 3 (TM7SF3), a seven transmembrane orphan receptor, as an inhibitor of cytokine-induced death of pancreatic beta cells

(2011) A. Beck et al.   DIABETOLOGIA

DEGRADE, MOVE, REGROUP: signaling control of splicing proteins

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SR and SR-related proteins redistribute to segregated fibrillar components of nucleoli in a response to DNA damage

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Identification of Nuclear Phosphatidylinositol 4,5-Bisphosphate-Interacting Proteins by Neomycin Extraction

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Simple Combinations of Lineage-Determining Transcription Factors Prime cis-Regulatory Elements Required for Macrophage and B Cell Identities

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Expansion of the eukaryotic proteome by alternative splicing

(2010) Timothy W. Nilsen et al.   NATURE

The RNA binding protein Larp1 regulates cell division, apoptosis and cell migration

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B23 acts as a nucleolar stress sensor and promotes cell survival through its dynamic interaction with hnRNPU and hnRNPA1

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Identification of novel ribonucleo-protein complexes from the brain-specific snoRNA MBII-52

(2010) Y. Soeno et al.   RNA

Nuclear Speckles

(2010) D. L. Spector et al.   Cold Spring Harbor Perspectives in Biology

Mechanisms of alternative splicing regulation: insights from molecular and genomics approaches

(2009) Mo Chen et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Detailed close-ups and the big picture of spliceosomes

(2008) Melissa S Jurica   CURRENT OPINION IN STRUCTURAL BIOLOGY

Phosphoproteome Analysis ofDrosophila melanogasterEmbryos

(2008) Bo Zhai et al.   JOURNAL OF PROTEOME RESEARCH

G Protein-Coupled Receptors in and on the Cell Nucleus: A New Signaling Paradigm?

(2008) BENOIT BOIVIN et al.   JOURNAL OF RECEPTORS AND SIGNAL TRANSDUCTION

A PtdIns4,5P2-regulated nuclear poly(A) polymerase controls expression of select mRNAs

(2008) David L. Mellman et al.   NATURE