Augmented cellular uptake and homologous targeting of exosome-based drug loaded IOL for posterior capsular opacification prevention and biosafety improvement

Drug-Eluting Hydrophilic Coating Modification of Intraocular Lens via Facile Dopamine Self-Polymerization for Posterior Capsular Opacification Prevention

(2021) Sihao Liu et al.   ACS Biomaterials-Science & Engineering

Tumor Exosomes Reprogrammed by Low pH Are Efficient Targeting Vehicles for Smart Drug Delivery and Personalized Therapy against their Homologous Tumor

(2021) Changguo Gong et al.   Advanced Science

Mesenchymal stromal exosome–functionalized scaffolds induce innate and adaptive immunomodulatory responses toward tissue repair

(2021) Ni Su et al.   Science Advances

Exosome-eluting stents for vascular healing after ischaemic injury

(2021) Shiqi Hu et al.   Nature Biomedical Engineering

Inflammatory tumor microenvironment responsive neutrophil exosomes-based drug delivery system for targeted glioma therapy

(2021) Jun Wang et al.   BIOMATERIALS

Urinary exosomes-based Engineered Nanovectors for Homologously Targeted Chemo-Chemodynamic Prostate Cancer Therapy via abrogating EGFR/AKT/NF-kB/IkB signaling

(2021) Shaojun Pan et al.   BIOMATERIALS

Reduction of choroidal neovascularization via cleavable VEGF antibodies conjugated to exosomes derived from regulatory T cells

(2021) Ying Tian et al.   Nature Biomedical Engineering

Drug-eluting intraocular lens with sustained bromfenac release for conquering posterior capsular opacification

(2021) Xiaobo Zhang et al.   Bioactive Materials

Exosome-functionalized polyetheretherketone-based implant with immunomodulatory property for enhancing osseointegration

(2021) Lei Fan et al.   Bioactive Materials

Centrifugally concentric ring-patterned drug-loaded polymeric coating as an intraocular lens surface modification for efficient prevention of posterior capsular opacification

(2021) Duoduo Lu et al.   Acta Biomaterialia

Cascade catalytic platform modified intraocular lens for high-efficient posterior capsule opacification prevention

(2021) Huiying Huang et al.   CHEMICAL ENGINEERING JOURNAL

Photo-responsive intraocular lens with on demand drug release for posterior capsule opacification prevention and improved biosafety

(2021) Jiayi Xia et al.   CHEMICAL ENGINEERING JOURNAL

Extracellular Vesicle and Particle Biomarkers Define Multiple Human Cancers

(2020) Ayuko Hoshino et al.   CELL

Feasibility of Mechanical Extrusion to Coat Nanoparticles with Extracellular Vesicle Membranes

(2020) Jan Van Deun et al.   Cells

Dual drug delivery from hydrophobic and hydrophilic intraocular lenses: in-vitro and in-vivo studies

(2020) Ana Topete et al.   JOURNAL OF CONTROLLED RELEASE

Causes of blindness and vision impairment in 2020 and trends over 30 years, and prevalence of avoidable blindness in relation to VISION 2020: the Right to Sight: an analysis for the Global Burden of Disease Study

(2020) Jaimie D Steinmetz et al.   Lancet Global Health

Tumor-Derived Extracellular Vesicles Breach the Intact Blood–Brain Barrier via Transcytosis

(2019) Golnaz Morad et al.   ACS Nano

Anti-Adhesive And Antiproliferative Synergistic Surface Modification Of Intraocular Lens For Reduced Posterior Capsular Opacification

(2019) Yuemei Han et al.   International Journal of Nanomedicine

Posterior capsule opacification rate after phacoemulsification in pediatric cataract: Hydrophilic versus hydrophobic intraocular lenses

(2019) Pradhnya Sen et al.   JOURNAL OF CATARACT AND REFRACTIVE SURGERY

Exosome biogenesis, bioactivities and functions as new delivery systems of natural compounds

(2018) Ammad Ahmad Farooqi et al.   BIOTECHNOLOGY ADVANCES

Self-Assembly of Extracellular Vesicle-like Metal–Organic Framework Nanoparticles for Protection and Intracellular Delivery of Biofunctional Proteins

(2018) Gong Cheng et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Exosome as a Novel Shuttle for Delivery of Therapeutics across Biological Barriers

(2018) Chandan Kanta Das et al.   MOLECULAR PHARMACEUTICS

Rate of retinal tear and detachment after neodymium:YAG capsulotomy

(2017) Jason D. Wesolosky et al.   JOURNAL OF CATARACT AND REFRACTIVE SURGERY

Cataracts

(2017) Yu-Chi Liu et al.   LANCET

UV-assisted treatment on hydrophobic acrylic IOLs anterior surface with methacryloyloxyethyl phosphorylcholine: Reducing inflammation and maintaining low posterior capsular opacification properties

(2017) Xiaodan Huang et al.   Materials Science & Engineering C-Materials for Biological Applications

Exosomes facilitate therapeutic targeting of oncogenic KRAS in pancreatic cancer

(2017) Sushrut Kamerkar et al.   NATURE

Exosomes in Cancer Nanomedicine and Immunotherapy: Prospects and Challenges

(2017) Nicholas L. Syn et al.   TRENDS IN BIOTECHNOLOGY

Extracellular vesicles for drug delivery

(2016) Pieter Vader et al.   ADVANCED DRUG DELIVERY REVIEWS

A novel capsular tension ring as local sustained-release carrier for preventing posterior capsule opacification

(2016) Ming Lei et al.   BIOMATERIALS

Bottom-up fabrication of zwitterionic polymer brushes on intraocular lens for improved biocompatibility

(2016) Yuemei Han et al.   International Journal of Nanomedicine

Revisiting secondary capsulotomy for posterior capsule management in pediatric cataract surgery

(2016) Zachary P. Elkin et al.   JOURNAL OF AAPOS

Surface PEGylation of intraocular lens for PCO prevention: An in vivo evaluation

(2016) Xu Xu et al.   JOURNAL OF BIOMATERIALS APPLICATIONS

Development of exosome-encapsulated paclitaxel to overcome MDR in cancer cells

(2016) Myung Soo Kim et al.   Nanomedicine-Nanotechnology Biology and Medicine

ISGylation controls exosome secretion by promoting lysosomal degradation of MVB proteins

(2016) Carolina Villarroya-Beltri et al.   Nature Communications

Prospective Randomized Intraindividual Comparison of Posterior Capsule Opacification After Implantation of an IOL With and Without Heparin Surface Modification

(2015) Eva M. Krall et al.   JOURNAL OF REFRACTIVE SURGERY

Exogenous DNA Loading into Extracellular Vesicles via Electroporation is Size-Dependent and Enables Limited Gene Delivery

(2015) Tek N. Lamichhane et al.   MOLECULAR PHARMACEUTICS

Engineering and functionalization of biomaterials via surface modification

(2015) Guosong Wu et al.   Journal of Materials Chemistry B

Five-year incidence of Nd:YAG laser capsulotomy and association with in vitro proliferation of lens epithelial cells from individual specimens: a case control study

(2014) Karin Sundelin et al.   BMC Ophthalmology

A doxorubicin delivery platform using engineered natural membrane vesicle exosomes for targeted tumor therapy

(2013) Yanhua Tian et al.   BIOMATERIALS

Hydrophilic Acrylic Intraocular Lens as a Drug Delivery System: Influence of the Presoaking Time and Comparison to Intracameral Injection

(2012) Inna Lipnitzki et al.   JOURNAL OF OCULAR PHARMACOLOGY AND THERAPEUTICS