Comprehensive analysis and validation of novel immune and vascular remodeling related genes signature associated with drug interactions in pulmonary arterial hypertension

Identifying Potential Mitochondrial Proteome Signatures Associated with the Pathogenesis of Pulmonary Arterial Hypertension in the Rat Model

(2022) Jie Wang et al.   Oxidative Medicine and Cellular Longevity

Altered Cellular Immunity and Differentially Expressed Immune-Related Genes in Patients With Systemic Sclerosis–Associated Pulmonary Arterial Hypertension

(2022) Jianxin Tu et al.   Frontiers in Immunology

Expression of SARS-COV-2 cell receptor gene ACE2 is associated with immunosuppression and metabolic reprogramming in lung adenocarcinoma based on bioinformatics analyses of gene expression profiles

(2021) Md Nazim Uddin et al.   CHEMICO-BIOLOGICAL INTERACTIONS

BCL11B Regulates Arterial Stiffness and Related Target Organ Damage

(2021) Jeff Arni C Valisno et al.   CIRCULATION RESEARCH

Inhibition of Mitogen-Activated Protein Kinase (MAPK)-Activated Protein Kinase 2 (MK2) is Protective in Pulmonary Hypertension

(2021) Mohammad Shafiq et al.   HYPERTENSION

The reactome pathway knowledgebase 2022

(2021) Marc Gillespie et al.   NUCLEIC ACIDS RESEARCH

Platelet Glycolytic Metabolism Correlates with Hemodynamic Severity in Pulmonary Arterial Hypertension

(2020) Ruth E McDowell et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Impact of Nutrition on Pulmonary Arterial Hypertension

(2020) María Callejo et al.   Nutrients

Protein expression profile changes of lung tissue in patients with pulmonary hypertension

(2020) Min Wu et al.   PeerJ

Whole Blood RNA Profiles Associated with Pulmonary Arterial Hypertension and Clinical Outcome

(2020) Christopher J Rhodes et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

RNA Signaling in Pulmonary Arterial Hypertension—A Double-Stranded Sword

(2020) Helena A. Turton et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

RNA-Binding Proteins in Pulmonary Hypertension

(2020) Hui Zhang et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Integrative analyses of gene expression profile reveal potential crucial roles of mitotic cell cycle and microtubule cytoskeleton in pulmonary artery hypertension

(2020) Jing Luo et al.   BMC Medical Genomics

RUNX3-dependent oxidative epithelial-to-mesenchymal transition in methamphetamine-induced chronic lung injury

(2020) Lin Shi et al.   CELL STRESS & CHAPERONES

Screening and Identification of Therapeutic Targets for Pulmonary Arterial Hypertension Through Microarray Technology

(2020) Qing Li et al.   Frontiers in Genetics

When Innate Immunity Meets Angiogenesis—The Role of Toll-Like Receptors in Endothelial Cells and Pulmonary Hypertension

(2020) Aneel Bhagwani et al.   Frontiers in Medicine

Myocardial proteomic profile in pulmonary arterial hypertension

(2020) Mateusz K. Hołda et al.   Scientific Reports

Perivascular Inflammation in Pulmonary Arterial Hypertension

(2020) Yijie Hu et al.   Cells

Dendritic Cell Subsets and Effector Function in Idiopathic and Connective Tissue Disease-Associated Pulmonary Arterial Hypertension

(2019) Denise van Uden et al.   Frontiers in Immunology

Meta-analysis of blood genome-wide expression profiling studies in pulmonary arterial hypertension

(2019) Jason M. Elinoff et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Inflammatory Macrophage Expansion in Pulmonary Hypertension Depends upon Mobilization of Blood-Borne Monocytes

(2018) Jonathan Florentin et al.   JOURNAL OF IMMUNOLOGY

A Comprehensive Immunologic Portrait of Triple-Negative Breast Cancer

(2018) Zhixian Liu et al.   Translational Oncology

Global Proteomics Deciphered Novel-Function of Osthole Against Pulmonary Arterial Hypertension

(2018) Li Yao et al.   Scientific Reports

Mitochondrial metabolism in pulmonary hypertension: beyond mountains there are mountains

(2018) Miranda K. Culley et al.   JOURNAL OF CLINICAL INVESTIGATION

Candidate Biomarkers and Molecular Mechanism Investigation for Glioblastoma Multiforme Utilizing WGCNA

(2018) Qi Yang et al.   Biomed Research International

STRING v11: protein–protein association networks with increased coverage, supporting functional discovery in genome-wide experimental datasets

(2018) Damian Szklarczyk et al.   NUCLEIC ACIDS RESEARCH

Pan-cancer analysis of transcriptional metabolic dysregulation using The Cancer Genome Atlas

(2018) S. R. Rosario et al.   Nature Communications

Annexin A2 supports pulmonary microvascular integrity by linking vascular endothelial cadherin and protein tyrosine phosphatases

(2017) Min Luo et al.   JOURNAL OF EXPERIMENTAL MEDICINE

ggplot2 - Elegant Graphics for Data Analysis (2nd Edition)

(2017) Virgilio Gómez-Rubio   Journal of Statistical Software

DGIdb 3.0: a redesign and expansion of the drug–gene interaction database

(2017) Kelsy C Cotto et al.   NUCLEIC ACIDS RESEARCH

Tumor aneuploidy correlates with markers of immune evasion and with reduced response to immunotherapy

(2017) Teresa Davoli et al.   SCIENCE

Regulation of Pulmonary Vascular Smooth Muscle Contractility in Pulmonary Arterial Hypertension: Implications for Therapy

(2017) Melissa A. Lyle et al.   Frontiers in Physiology

Increased Pyruvate Dehydrogenase Kinase 4 Expression in Lung Pericytes Is Associated with Reduced Endothelial-Pericyte Interactions and Small Vessel Loss in Pulmonary Arterial Hypertension

(2016) Ke Yuan et al.   AMERICAN JOURNAL OF PATHOLOGY

Pulmonary vascular remodeling in pulmonary hypertension

(2016) Rubin M. Tuder   CELL AND TISSUE RESEARCH

The role of genetics in pulmonary arterial hypertension

(2016) Lijiang Ma et al.   JOURNAL OF PATHOLOGY

KEGG: new perspectives on genomes, pathways, diseases and drugs

(2016) Minoru Kanehisa et al.   NUCLEIC ACIDS RESEARCH

Dissecting the multicellular ecosystem of metastatic melanoma by single-cell RNA-seq

(2016) I. Tirosh et al.   SCIENCE

Overexpression of RPS27a contributes to enhanced chemoresistance of CML cells to imatinib by the transactivated STAT3

(2016) Houcai Wang et al.   Oncotarget

Transcription Factors, Transcriptional Coregulators, and Epigenetic Modulation in the Control of Pulmonary Vascular Cell Phenotype: Therapeutic Implications for Pulmonary Hypertension (2015 Grover Conference Series)

(2016) Soni S. Pullamsetti et al.   Pulmonary Circulation

Novel Signaling Pathways in Pulmonary Arterial Hypertension (2015 Grover Conference Series)

(2016) Keytam S. Awad et al.   Pulmonary Circulation

Roles of transcriptional factor 7 in production of inflammatory factors for lung diseases

(2015) Yichun Zhu et al.   Journal of Translational Medicine

NetworkAnalyst for statistical, visual and network-based meta-analysis of gene expression data

(2015) Jianguo Xia et al.   Nature Protocols

cytoHubba: identifying hub objects and sub-networks from complex interactome

(2014) Chia-Hao Chin et al.   BMC Systems Biology

Inflammation and Immunity in the Pathogenesis of Pulmonary Arterial Hypertension

(2014) Marlene Rabinovitch et al.   CIRCULATION RESEARCH

Genetic Deletion of Toll-Like Receptor 4 on Platelets Attenuates Experimental Pulmonary Hypertension

(2014) Eileen M. Bauer et al.   CIRCULATION RESEARCH

Systematic Analysis of Blood Cell Transcriptome in End-Stage Chronic Respiratory Diseases

(2014) Julie Chesné et al.   PLoS One

Inflammatory cytokines in pulmonary hypertension

(2014) Alexandra Groth et al.   RESPIRATORY RESEARCH

iRegulon: From a Gene List to a Gene Regulatory Network Using Large Motif and Track Collections

(2014) Rekin's Janky et al.   PLoS Computational Biology

The role of hypoxia in pulmonary vascular diseases: a perspective

(2013) Norbert F. Voelkel et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Increased Expression of Endoplasmic Reticulum Stress and Unfolded Protein Response Genes in Peripheral Blood Mononuclear Cells From Patients With Limited Cutaneous Systemic Sclerosis and Pulmonary Arterial Hypertension

(2013) Stefania Lenna et al.   ARTHRITIS AND RHEUMATISM

GSVA: gene set variation analysis for microarray and RNA-Seq data

(2013) Sonja Hänzelmann et al.   BMC BIOINFORMATICS

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(2013) Larissa A. Shimoda et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

Signal Transduction in the Development of Pulmonary Arterial Hypertension

(2013) Simon Malenfant et al.   Pulmonary Circulation

Erythroid-Specific Transcriptional Changes in PBMCs from Pulmonary Hypertension Patients

(2012) Chris Cheadle et al.   PLoS One

Immune and inflammatory mechanisms in pulmonary arterial hypertension

(2012) Hala El Chami et al.   PROGRESS IN CARDIOVASCULAR DISEASES

pROC: an open-source package for R and S+ to analyze and compare ROC curves

(2011) Xavier Robin et al.   BMC BIOINFORMATICS

Altered Immune Phenotype in Peripheral Blood Cells of Patients with Scleroderma-Associated Pulmonary Hypertension

(2010) Michael G Risbano et al.   CTS-Clinical and Translational Science

Role of apoptosis in pulmonary hypertension: From experimental models to clinical trials

(2010) Paul Jurasz et al.   PHARMACOLOGY & THERAPEUTICS

Limited Systemic Sclerosis Patients with Pulmonary Arterial Hypertension Show Biomarkers of Inflammation and Vascular Injury

(2010) Sarah A. Pendergrass et al.   PLoS One

Bioinformatics enrichment tools: paths toward the comprehensive functional analysis of large gene lists

(2008) Da Wei Huang et al.   NUCLEIC ACIDS RESEARCH