Human retinal organoids harboring IMPG2 mutations exhibit a photoreceptor outer segment phenotype that models advanced retinitis pigmentosa

Cone photoreceptors in human stem cell-derived retinal organoids demonstrate intrinsic light responses that mimic those of primate fovea

(2022) Aindrila Saha et al.   Cell Stem Cell

The structure–function correlation analysed by OCT and full field ERG in typical and pericentral subtypes of retinitis pigmentosa

(2021) Ching-Wen Huang et al.   Scientific Reports

Measures of Function and Structure to Determine Phenotypic Features, Natural History, and Treatment Outcomes in Inherited Retinal Diseases

(2021) Artur V. Cideciyan et al.   Annual Review of Vision Science

Chemically induced senescence in human stem cell‐derived neurons promotes phenotypic presentation of neurodegeneration

(2021) Ali Fathi et al.   AGING CELL

Deletion of the Impg2 gene causes the degeneration of rod and cone cells in mice

(2020) Huijuan Xu et al.   HUMAN MOLECULAR GENETICS

Proteoglycan IMPG2 Shapes the Interphotoreceptor Matrix and Modulates Vision

(2020) Ezequiel M. Salido et al.   JOURNAL OF NEUROSCIENCE

Human iPSC Modeling Reveals Mutation-Specific Responses to Gene Therapy in a Genotypically Diverse Dominant Maculopathy

(2020) Divya Sinha et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Cell Types of the Human Retina and Its Organoids at Single-Cell Resolution

(2020) Cameron S. Cowan et al.   CELL

Retinal organoids: a window into human retinal development

(2020) Michelle O'Hara-Wright et al.   DEVELOPMENT

Homozygous and heterozygous retinal phenotypes in families harbouring IMPG2 mutations

(2019) Arif O. Khan et al.   OPHTHALMIC GENETICS

Extracellular matrix component expression in human pluripotent stem cell-derived retinal organoids recapitulates retinogenesis in vivo and reveals an important role for IMPG1 and CD44 in the development of photoreceptors and interphotoreceptor matrix

(2018) Majed Felemban et al.   Acta Biomaterialia

Phenotypic characterization of P23H and S334ter rhodopsin transgenic rat models of inherited retinal degeneration

(2018) Matthew M. LaVail et al.   EXPERIMENTAL EYE RESEARCH

Non-syndromic retinitis pigmentosa

(2018) Sanne K. Verbakel et al.   PROGRESS IN RETINAL AND EYE RESEARCH

Establishment of Immunodeficient Retinal Degeneration Model Mice and Functional Maturation of Human ESC-Derived Retinal Sheets after Transplantation

(2018) Satoshi Iraha et al.   Stem Cell Reports

Aging in a Dish: iPSC-Derived and Directly Induced Neurons for Studying Brain Aging and Age-Related Neurodegenerative Diseases

(2018) Jerome Mertens et al.   Annual Review of Genetics

Outer retinal layers as predictors of visual acuity in retinitis pigmentosa: a cross-sectional study

(2018) Keissy Sousa et al.   GRAEFES ARCHIVE FOR CLINICAL AND EXPERIMENTAL OPHTHALMOLOGY

Medium- to long-term survival and functional examination of human iPSC-derived retinas in rat and primate models of retinal degeneration

(2018) Hung-Ya Tu et al.   EBioMedicine

Mutations in the Genes for Interphotoreceptor Matrix Proteoglycans, IMPG1 and IMPG2, in Patients with Vitelliform Macular Lesions

(2017) Caroline Brandl et al.   Genes

Structure and function of the interphotoreceptor matrix surrounding retinal photoreceptor cells

(2015) Makoto Ishikawa et al.   EXPERIMENTAL EYE RESEARCH

A new immunodeficient pigmented retinal degenerate rat strain to study transplantation of human cells without immunosuppression

(2014) Magdalene J. Seiler et al.   GRAEFES ARCHIVE FOR CLINICAL AND EXPERIMENTAL OPHTHALMOLOGY

Frequency and Clinical Pattern of Vitelliform Macular Dystrophy Caused by Mutations of Interphotoreceptor Matrix IMPG1 and IMPG2 Genes

(2014) Isabelle Meunier et al.   OPHTHALMOLOGY

Self-Formation of Optic Cups and Storable Stratified Neural Retina from Human ESCs

(2012) Tokushige Nakano et al.   Cell Stem Cell

iPS cell modeling of Best disease: insights into the pathophysiology of an inherited macular degeneration

(2012) Ruchira Singh et al.   HUMAN MOLECULAR GENETICS

Optic Vesicle-like Structures Derived from Human Pluripotent Stem Cells Facilitate a Customized Approach to Retinal Disease Treatment

(2011) Jason S. Meyer et al.   STEM CELLS

Mutations in IMPG2, Encoding Interphotoreceptor Matrix Proteoglycan 2, Cause Autosomal-Recessive Retinitis Pigmentosa

(2010) Dikla Bandah-Rozenfeld et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Morphological changes of short-wavelength cones in the developing S334ter-3 transgenic rat

(2010) Jose R. Hombrebueno et al.   BRAIN RESEARCH

Retinal degeneration in two lines of transgenic S334ter rats

(2010) G. Martinez-Navarrete et al.   EXPERIMENTAL EYE RESEARCH