iPS cell modeling of Best disease: insights into the pathophysiology of an inherited macular degeneration

Modeling Brain Disease in a Dish: Really?

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Mitochondrial Dysfunction in Retinal Diseases

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Embryonic stem cell trials for macular degeneration: a preliminary report

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Modelling schizophrenia using human induced pluripotent stem cells

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Modelling the long QT syndrome with induced pluripotent stem cells

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Genetic correction and analysis of induced pluripotent stem cells from a patient with gyrate atrophy

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Human Induced Pluripotent Stem-Derived Retinal Pigment Epithelium (RPE) Cells Exhibit Ion Transport, Membrane Potential, Polarized Vascular Endothelial Growth Factor Secretion, and Gene Expression Pattern Similar to Native RPE

(2011) Maria Kokkinaki et al.   STEM CELLS

Optic Vesicle-like Structures Derived from Human Pluripotent Stem Cells Facilitate a Customized Approach to Retinal Disease Treatment

(2011) Jason S. Meyer et al.   STEM CELLS

Molecular signature of primary retinal pigment epithelium and stem-cell-derived RPE cells

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The role of calcium signaling in phagocytosis

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Bestrophins and retinopathies

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The presence of bestrophin-1 modulates the Ca2+ recruitment from Ca2+ stores in the ER

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Directed differentiation of human induced pluripotent stem cells: a retina perspective

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Hereditary macular degeneration (HMD) in 246 cases traced to one gene-source in central Sweden

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A protocol for the culture and differentiation of highly polarized human retinal pigment epithelial cells

(2009) Shozo Sonoda et al.   Nature Protocols

ER-localized bestrophin 1 activates Ca2+-dependent ion channels TMEM16A and SK4 possibly by acting as a counterion channel

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Protective Effects of Human iPS-Derived Retinal Pigment Epithelium Cell Transplantation in the Retinal Dystrophic Rat

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Generation of pluripotent stem cells from patients with type 1 diabetes

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Modeling early retinal development with human embryonic and induced pluripotent stem cells

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Functional roles of bestrophins in ocular epithelia

(2009) Alan D. Marmorstein et al.   PROGRESS IN RETINAL AND EYE RESEARCH

The spectrum of ocular phenotypes caused by mutations in the BEST1 gene

(2009) Camiel J.F. Boon et al.   PROGRESS IN RETINAL AND EYE RESEARCH

Derivation of Functional Retinal Pigmented Epithelium from Induced Pluripotent Stem Cells

(2009) David E. Buchholz et al.   STEM CELLS

Bestrophin Cl− channels are highly permeable to HCO3−

(2008) Zhiqiang Qu et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Disease-Specific Induced Pluripotent Stem Cells

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Elucidating the phenomenon of HESC-derived RPE: Anatomy of cell genesis, expansion and retinal transplantation

(2008) Anthony Vugler et al.   EXPERIMENTAL NEUROLOGY

Induced pluripotent stem cells from a spinal muscular atrophy patient

(2008) Allison D. Ebert et al.   NATURE

Generation of human-induced pluripotent stem cells

(2008) In-Hyun Park et al.   Nature Protocols

Molecular Physiology of Bestrophins: Multifunctional Membrane Proteins Linked to Best Disease and Other Retinopathies

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