Identification and Quantitation of Novel ABI3 Isoforms Relative to Alzheimer’s Disease Genetics and Neuropathology

An Alternatively Spliced TREM2 Isoform Lacking the Ligand Binding Domain is Expressed in Human Brain

(2022) Benjamin C. Shaw et al.   JOURNAL OF ALZHEIMERS DISEASE

Deletion of Abi3/Gngt2 influences age-progressive amyloid β and tau pathologies in distinctive ways

(2022) Kristen R. Ibanez et al.   Alzheimers Research & Therapy

APOΕ4 lowers energy expenditure in females and impairs glucose oxidation by increasing flux through aerobic glycolysis

(2021) Brandon C. Farmer et al.   Molecular Neurodegeneration

A genome-wide association study with 1,126,563 individuals identifies new risk loci for Alzheimer’s disease

(2021) Douglas P. Wightman et al.   NATURE GENETICS

Analysis of Genetic Variants Associated with Levels of Immune Modulating Proteins for Impact on Alzheimer’s Disease Risk Reveal a Potential Role for SIGLEC14

(2021) Benjamin C. Shaw et al.   Genes

New findings on GFP-like protein application as fluorescent tags: Fibrillogenesis, oligomerization, and amorphous aggregation

(2021) Olga V. Stepanenko et al.   INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

Deletion of Abi3 gene locus exacerbates neuropathological features of Alzheimer’s disease in a mouse model of Aβ amyloidosis

(2021) Hande Karahan et al.   Science Advances

Effects of advanced age upon astrocyte-specific responses to acute traumatic brain injury in mice

(2020) Alexandria N. Early et al.   Journal of Neuroinflammation

Examination of the Effect of Rare Variants in TREM2, ABI3, and PLCG2 in LOAD Through Multiple Phenotypes

(2020) Claudia Olive et al.   JOURNAL OF ALZHEIMERS DISEASE

GFP fluorescence tagging alters dynamin-related protein 1 oligomerization dynamics and creates disassembly-refractory puncta to mediate mitochondrial fission

(2020) Felipe Montecinos-Franjola et al.   Scientific Reports

Association of ABI3 and PLCG2 missense variants with disease risk and neuropathology in Lewy body disease and progressive supranuclear palsy

(2020) Samantha L. Strickland et al.   Acta Neuropathologica Communications

Microglial Phagocytosis: A Disease-Associated Process Emerging from Alzheimer’s Disease Genetics

(2020) Anna Podleśny-Drabiniok et al.   TRENDS IN NEUROSCIENCES

Genome-wide meta-analysis identifies new loci and functional pathways influencing Alzheimer’s disease risk

(2019) Iris E. Jansen et al.   NATURE GENETICS

Transethnic meta-analysis of rare coding variants in PLCG2, ABI3, and TREM2 supports their general contribution to Alzheimer’s disease

(2019) Maria Carolina Dalmasso et al.   Translational Psychiatry

Common Variants in ABI3 Influence Cerebrospinal Fluid Total Tau Levels and Cognitive Decline in Progressive Mild Cognitive Impairment Patients

(2019) Li-Dong Niu et al.   JOURNAL OF ALZHEIMERS DISEASE

Rare coding variants in PLCG2, ABI3, and TREM2 implicate microglial-mediated innate immunity in Alzheimer's disease

(2017) Rebecca Sims et al.   NATURE GENETICS

TREM2 deficiency attenuates neuroinflammation and protects against neurodegeneration in a mouse model of tauopathy

(2017) Cheryl E. G. Leyns et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

ABI3, a component of the WAVE2 complex, is potentially regulated by PI3K/AKT pathway

(2017) Lais Moraes et al.   Oncotarget

Purification and Characterization of Progenitor and Mature Human Astrocytes Reveals Transcriptional and Functional Differences with Mouse

(2016) Ye Zhang et al.   NEURON

The NESH/Abi-3-based WAVE2 complex is functionally distinct from the Abi-1-based WAVE2 complex

(2015) Saki Sekino et al.   Cell Communication and Signaling

Genetics of CD33 in Alzheimer's disease and acute myeloid leukemia

(2015) M. Malik et al.   HUMAN MOLECULAR GENETICS

Host microbiota constantly control maturation and function of microglia in the CNS

(2015) Daniel Erny et al.   NATURE NEUROSCIENCE

An RNA-Sequencing Transcriptome and Splicing Database of Glia, Neurons, and Vascular Cells of the Cerebral Cortex

(2014) Y. Zhang et al.   JOURNAL OF NEUROSCIENCE

Abi Is Required for Modulation and Stability but Not Localization or Activation of the SCAR/WAVE Complex

(2013) Andrew J. Davidson et al.   EUKARYOTIC CELL

CD33 Alzheimer's Risk-Altering Polymorphism, CD33 Expression, and Exon 2 Splicing

(2013) M. Malik et al.   JOURNAL OF NEUROSCIENCE

The Genotype-Tissue Expression (GTEx) project

(2013) John Lonsdale et al.   NATURE GENETICS

Correlation of Alzheimer Disease Neuropathologic Changes With Cognitive Status: A Review of the Literature

(2012) Peter T. Nelson et al.   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY

NESH Regulates Dendritic Spine Morphology and Synapse Formation

(2012) Jeomil Bae et al.   PLoS One

Exploring the Human Leukocyte Phosphoproteome Using a Microfluidic Reversed-Phase−TiO2−Reversed-Phase High-Performance Liquid Chromatography Phosphochip Coupled to a Quadrupole Time-of-Flight Mass Spectrometer

(2010) Reinout Raijmakers et al.   ANALYTICAL CHEMISTRY

Discovery of Mouse Spleen Signaling Responses to Anthrax using Label-Free Quantitative Phosphoproteomics via Mass Spectrometry

(2010) Nathan P. Manes et al.   MOLECULAR & CELLULAR PROTEOMICS

Regulation of Tau Pathology by the Microglial Fractalkine Receptor

(2010) Kiran Bhaskar et al.   NEURON

Expression of SORL1 and a novel SORL1 splice variant in normal and Alzheimers disease brain

(2009) Karrie E Grear et al.   Molecular Neurodegeneration