Regulation of Atherosclerosis by Toll-Like Receptor 4 Induced by Serum Amyloid 1: A Systematic In Vitro Study

Computational molecular characterization of p53 and Human TLRs interactions

(2022) Mohammad JahoorAlam et al.   CELLULAR AND MOLECULAR BIOLOGY

Elevated SAA1 promotes the development of insulin resistance in ovarian granulosa cells in polycystic ovary syndrome

(2022) Qinling Zhu et al.   Reproductive Biology and Endocrinology

Activated Platelets Upregulate β2 Integrin Mac-1 (CD11b/CD18) on Dendritic Cells, Which Mediates Heterotypic Cell–Cell Interaction

(2022) Henry Nording et al.   JOURNAL OF IMMUNOLOGY

Serum amyloid A1 exacerbates hepatic steatosis via TLR4-mediated NF-κB signaling pathway

(2022) Bin Jiang et al.   Molecular Metabolism

Foam Cells in Atherosclerosis: Novel Insights Into Its Origins, Consequences, and Molecular Mechanisms

(2022) Yuzhou Gui et al.   Frontiers in Cardiovascular Medicine

Novel insights: Dynamic foam cells derived from the macrophage in atherosclerosis

(2021) Jun Li et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Marked Changes in Serum Amyloid A Distribution and High-Density Lipoprotein Structure during Acute Inflammation

(2021) Shitsuko Shimano et al.   Biomed Research International

Cardiovascular events and the role of accelerated atherosclerosis in systemic vasculitis

(2021) Alison H. Clifford et al.   ATHEROSCLEROSIS

Hepatocytes derived increased SAA1 promotes intrahepatic platelet aggregation and aggravates liver inflammation in NAFLD

(2021) Daoyuan Li et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Targeting inflammation in atherosclerosis — from experimental insights to the clinic

(2021) Oliver Soehnlein et al.   NATURE REVIEWS DRUG DISCOVERY

Platelet phagocytosis via PSGL1 and accumulation of microparticles in systemic sclerosis

(2021) Angelo A Manfredi et al.   Arthritis & Rheumatology

Serum Amyloid A1/Toll-Like Receptor-4 Axis, an Important Link between Inflammation and Outcome of TBI Patients

(2021) Víctor Farré-Alins et al.   Biomedicines

Inflammatory Mechanisms Contributing to Endothelial Dysfunction

(2021) Panagiotis Theofilis et al.   Biomedicines

Moderate dose alcohol protects against serum amyloid protein A1‐induced endothelial dysfunction via both notch‐dependent and notch‐independent pathways

(2021) Naresh K. Rajendran et al.   ALCOHOLISM-CLINICAL AND EXPERIMENTAL RESEARCH

Lipocalin-2 exerts pro-atherosclerotic effects as evidenced by in vitro and in vivo experiments

(2020) Koichiro Shibata et al.   HEART AND VESSELS

Ruscogenin alleviates LPS-induced pulmonary endothelial cell apoptosis by suppressing TLR4 signaling

(2020) Yunhao Wu et al.   BIOMEDICINE & PHARMACOTHERAPY

Serum Amyloid A1 (SAA1) Revisited: Restricted Leukocyte-Activating Properties of Homogeneous SAA1

(2020) Sara Abouelasrar Salama et al.   Frontiers in Immunology

Roles and Clinical Applications of Exosomes in Cardiovascular Disease

(2020) Dong Guo et al.   Biomed Research International

LDL receptors, caveolae and cholesterol in endothelial dysfunction: oxLDLs accomplices or victims?

(2020) Francesca Luchetti et al.   BRITISH JOURNAL OF PHARMACOLOGY

The vimentin rod domain blocks P-selectin-P-selectin glycoprotein ligand 1 interactions to attenuate leukocyte adhesion to inflamed endothelium

(2020) Fong Wilson Lam et al.   PLoS One

The turning away of serum amyloid A biological activities and receptor usage

(2020) Sara Abouelasrar Salama et al.   IMMUNOLOGY

Focal TLR4 activation mediates disturbed flow-induced endothelial inflammation

(2019) Dan Qu et al.   CARDIOVASCULAR RESEARCH

Silencing of SAA1 inhibits palmitate- or high-fat diet induced insulin resistance through suppression of the NF-κB pathway

(2019) Yong Wang et al.   MOLECULAR MEDICINE

The interaction between serum amyloid A and toll‐like receptor 2 pathway regulates inflammatory cytokine secretion in human gingival fibroblasts

(2019) Li‐Ting Song et al.   JOURNAL OF PERIODONTOLOGY

Down-regulation of Cx43 expression on PIH-HUVEC cells attenuates monocyte–endothelial adhesion

(2019) Xianlong Li et al.   THROMBOSIS RESEARCH

Serum amyloid A1 mediates myotube atrophy via Toll‐like receptors

(2019) Alexander Hahn et al.   Journal of Cachexia Sarcopenia and Muscle

Atherosclerosis

(2019) Peter Libby et al.   Nature Reviews Disease Primers

Lipid Management for the Prevention of Atherosclerotic Cardiovascular Disease

(2019) Erin D. Michos et al.   NEW ENGLAND JOURNAL OF MEDICINE

TLR4 (Toll-Like Receptor 4)-Dependent Signaling Drives Extracellular Catabolism of LDL (Low-Density Lipoprotein) Aggregates

(2019) Rajesh K. Singh et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Serum Amyloid A Is an Exchangeable Apolipoprotein

(2018) Patricia G. Wilson et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Lysophosphatidic Acid Promotes Expression and Activation of Matrix Metalloproteinase 9 (MMP9) in THP-1 Cells via Toll-Like Receptor 4/Nuclear Factor-κB (TLR4/NF-κB) Signaling Pathway

(2018) Zhi-bin Zhou et al.   MEDICAL SCIENCE MONITOR

Serum Amyloid A Contributes to Chronic Apical Periodontitis via TLR2 and TLR4

(2018) K. Hirai et al.   JOURNAL OF DENTAL RESEARCH

Platelet TLR4 at the crossroads of thrombosis and the innate immune response

(2018) Mirta Schattner   JOURNAL OF LEUKOCYTE BIOLOGY

The Potential of Fluocinolone Acetonide to Mitigate Inflammation and Lipid Accumulation in 2D and 3D Foam Cell Cultures

(2018) Luong T. H. Nguyen et al.   Biomed Research International

Intermittent Hypoxia Enhances THP-1 Monocyte Adhesion and Chemotaxis and Promotes M1 Macrophage Polarization via RAGE

(2018) Jing Zhou et al.   Biomed Research International

Baicalein protects against endothelial cell injury by inhibiting the TLR4/NF‑κB signaling pathway

(2017) Chun‑Xia Wan et al.   Molecular Medicine Reports

Induction of pro-inflammatory genes by serum amyloid A1 in human amnion fibroblasts

(2017) Wenjiao Li et al.   Scientific Reports

Ginsenoside F1 Ameliorates Endothelial Cell Inflammatory Injury and Prevents Atherosclerosis in Mice through A20-Mediated Suppression of NF-kB Signaling

(2017) Meng Qin et al.   Frontiers in Pharmacology

Serum amyloid A1 levels and amyloid deposition following a high-fat diet challenge in transgenic mice overexpressing hepatic serum amyloid A1

(2016) Woo Young Jang et al.   Applied Physiology Nutrition and Metabolism

Endothelial Cell Dysfunction and the Pathobiology of Atherosclerosis

(2016) Michael A. Gimbrone et al.   CIRCULATION RESEARCH

Emerging functions of serum amyloid A in inflammation

(2015) Richard D. Ye et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Puerarin Inhibits oxLDL-Induced Macrophage Activation and Foam Cell Formation in Human THP1 Macrophage

(2015) Heng Zhang et al.   Biomed Research International

Serum Amyloid A Truncations in Type 2 Diabetes Mellitus

(2015) Hussein N. Yassine et al.   PLoS One

Serum amyloid A1 isoforms display different efficacy at Toll-like receptor 2 and formyl peptide receptor 2

(2014) Mingjie Chen et al.   IMMUNOBIOLOGY

Serum amyloid A induces interleukin-6 in dermal fibroblasts via Toll-like receptor 2, interleukin-1 receptor-associated kinase 4 and nuclear factor-κB

(2014) Steven O'Reilly et al.   IMMUNOLOGY

A brief elevation of serum amyloid A is sufficient to increase atherosclerosis

(2014) Joel C. Thompson et al.   JOURNAL OF LIPID RESEARCH

Role of formyl peptide receptor 2 on the serum amyloid A-induced macrophage foam cell formation

(2013) Ha Young Lee et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Serum amyloid A stimulates macrophage foam cell formation via lectin-like oxidized low-density lipoprotein receptor 1 upregulation

(2013) Ha Young Lee et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Acute-phase serum amyloid A: Perspectives on its physiological and pathological roles

(2012) Robert Kisilevsky et al.   AMYLOID-JOURNAL OF PROTEIN FOLDING DISORDERS

Serum Amyloid A Activates the NLRP3 Inflammasome via P2X7 Receptor and a Cathepsin B-Sensitive Pathway

(2011) K. Niemi et al.   JOURNAL OF IMMUNOLOGY

Unknown

(2011) Zhe Dong et al.   MOLECULAR MEDICINE

CD36 Is a Novel Serum Amyloid A (SAA) Receptor Mediating SAA Binding and SAA-induced Signaling in Human and Rodent Cells

(2010) Irina N. Baranova et al.   JOURNAL OF BIOLOGICAL CHEMISTRY