Hepatocytes derived increased SAA1 promotes intrahepatic platelet aggregation and aggravates liver inflammation in NAFLD

Silencing of SAA1 inhibits palmitate- or high-fat diet induced insulin resistance through suppression of the NF-κB pathway

(2019) Yong Wang et al.   MOLECULAR MEDICINE

Diagnosis and management of non-alcoholic fatty liver disease

(2019) Erica Jennison et al.   POSTGRADUATE MEDICAL JOURNAL

Serum Amyloid A Is an Exchangeable Apolipoprotein

(2018) Patricia G. Wilson et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Serum amyloid A3 is pro-atherogenic

(2018) Joel C. Thompson et al.   ATHEROSCLEROSIS

Suppression of TLR4 activation by resveratrol is associated with STAT3 and Akt inhibition in oxidized low-density lipoprotein-activated platelets

(2018) Jie Sun et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Molecular pathways of nonalcoholic fatty liver disease development and progression

(2018) Fernando Bessone et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Novel phosphatidylethanolamine derivatives accumulate in circulation in hyperlipidemicApoE−/−mice and activate platelets via TLR2

(2016) Sudipta Biswas et al.   BLOOD

Serum amyloid A1: Structure, function and gene polymorphism

(2016) Lei Sun et al.   GENE

Platelets: No longer bystanders in liver disease

(2016) Abhishek Chauhan et al.   HEPATOLOGY

Nonalcoholic Fatty Liver Disease

(2015) Mary E. Rinella   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Reversibility of liver fibrosis

(2015) Mengxi Sun et al.   Clinics and Research in Hepatology and Gastroenterology

Metabolic Activation of Intrahepatic CD8+ T Cells and NKT Cells Causes Nonalcoholic Steatohepatitis and Liver Cancer via Cross-Talk with Hepatocytes

(2014) Monika Julia Wolf et al.   CANCER CELL

Serum amyloid A1 isoforms display different efficacy at Toll-like receptor 2 and formyl peptide receptor 2

(2014) Mingjie Chen et al.   IMMUNOBIOLOGY

Macrophage heterogeneity in liver injury and fibrosis

(2014) Frank Tacke et al.   JOURNAL OF HEPATOLOGY

Cutting Edge: TLR2 Is a Functional Receptor for Acute-Phase Serum Amyloid A

(2014) N. Cheng et al.   JOURNAL OF IMMUNOLOGY

A brief elevation of serum amyloid A is sufficient to increase atherosclerosis

(2014) Joel C. Thompson et al.   JOURNAL OF LIPID RESEARCH

Interaction of Kupffer Cells and Platelets Determines the Severity of Ischemia-Reperfusion Injury in Steatosis

(2014) Koichi Ogawa et al.   TOHOKU JOURNAL OF EXPERIMENTAL MEDICINE

Anti-platelet therapy in the prevention of hepatitis B virus-associated hepatocellular carcinoma

(2013) Giovanni Sitia et al.   JOURNAL OF HEPATOLOGY

Hepatic sinusoidal endothelium avidly binds platelets in an integrin-dependent manner, leading to platelet and endothelial activation and leukocyte recruitment

(2012) Patricia F. Lalor et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Acute-phase serum amyloid A: Perspectives on its physiological and pathological roles

(2012) Robert Kisilevsky et al.   AMYLOID-JOURNAL OF PROTEIN FOLDING DISORDERS

Interaction between Kupffer cells and platelets in the early period of hepatic ischemia–reperfusion injury—An in vivo study

(2012) Takafumi Tamura et al.   JOURNAL OF SURGICAL RESEARCH

Systematic review: the epidemiology and natural history of non-alcoholic fatty liver disease and non-alcoholic steatohepatitis in adults

(2011) G. Vernon et al.   ALIMENTARY PHARMACOLOGY & THERAPEUTICS

Mean platelet volume as a marker of increased cardiovascular risk in patients with nonalcoholic steatohepatitis

(2011) Naim Alkhouri et al.   HEPATOLOGY

Serum Amyloid A Activates the NLRP3 Inflammasome via P2X7 Receptor and a Cathepsin B-Sensitive Pathway

(2011) K. Niemi et al.   JOURNAL OF IMMUNOLOGY

Unknown

(2011) Zhe Dong et al.   MOLECULAR MEDICINE

Prevalence of Nonalcoholic Fatty Liver Disease and Nonalcoholic Steatohepatitis Among a Largely Middle-Aged Population Utilizing Ultrasound and Liver Biopsy: A Prospective Study

(2010) Christopher D. Williams et al.   GASTROENTEROLOGY

CD36 Is a Novel Serum Amyloid A (SAA) Receptor Mediating SAA Binding and SAA-induced Signaling in Human and Rodent Cells

(2010) Irina N. Baranova et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Rho-kinase inhibitor Y-27632 inhibits cholestasis-induced platelet interactions in the hepatic microcirculation

(2009) Matthias W. Laschke et al.   MICROVASCULAR RESEARCH

International Union of Basic and Clinical Pharmacology. LXXIII. Nomenclature for the Formyl Peptide Receptor (FPR) Family

(2009) R. D. Ye et al.   PHARMACOLOGICAL REVIEWS

Mean platelet volume in patients with non-alcoholic fatty liver disease

(2009) Hakan Ozhan et al.   PLATELETS

Is serum amyloid A an endogenous TLR4 agonist?

(2008) Silvana Sandri et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Aggravation of viral hepatitis by platelet-derived serotonin

(2008) Philipp A Lang et al.   NATURE MEDICINE