Credibility assessment of patient-specific computational modeling using patient-specific cardiac modeling as an exemplar

Linking statistical shape models and simulated function in the healthy adult human heart

(2021) Cristobal Rodero et al.   PLoS Computational Biology

A Framework for the generation of digital twins of cardiac electrophysiology from clinical 12-leads ECGs

(2021) Karli Gillette et al.   MEDICAL IMAGE ANALYSIS

The ‘Digital Twin’ to enable the vision of precision cardiology

(2020) Jorge Corral-Acero et al.   EUROPEAN HEART JOURNAL

Personalized Perioperative Multi-scale, Multi-physics Heart Simulation of Double Outlet Right Ventricle

(2020) Taro Kariya et al.   ANNALS OF BIOMEDICAL ENGINEERING

Constructing a Human Atrial Fibre Atlas

(2020) Caroline H. Roney et al.   ANNALS OF BIOMEDICAL ENGINEERING

A computational investigation into rate-dependant vectorcardiogram changes due to specific fibrosis patterns in non-ischæmic dilated cardiomyopathy

(2020) Philip M. Gemmell et al.   COMPUTERS IN BIOLOGY AND MEDICINE

His-bundle and left bundle pacing with optimized atrioventricular delay achieve superior electrical synchrony over endocardial and epicardial pacing in left bundle branch block patients

(2020) Marina Strocchi et al.   HEART RHYTHM

A publicly available virtual cohort of four-chamber heart meshes for cardiac electro-mechanics simulations

(2020) Marina Strocchi et al.   PLoS One

Validation of Wall Shear Stress Assessment in Non-invasive Coronary CTA versus Invasive Imaging: A Patient-Specific Computational Study

(2020) Parastou Eslami et al.   ANNALS OF BIOMEDICAL ENGINEERING

Integration of activation maps of epicardial veins in computational cardiac electrophysiology

(2020) Simone Stella et al.   COMPUTERS IN BIOLOGY AND MEDICINE

Reconstruction of three-dimensional biventricular activation based on the 12-lead electrocardiogram via patient-specific modelling

(2020) Simone Pezzuto et al.   EUROPACE

Using machine learning to identify local cellular properties that support re-entrant activation in patient-specific models of atrial fibrillation

(2020) Cesare Corrado et al.   EUROPACE

Data-Driven Uncertainty Quantification for Cardiac Electrophysiological Models: Impact of Physiological Variability on Action Potential and Spiral Wave Dynamics

(2020) Pras Pathmanathan et al.   Frontiers in Physiology

Pacing in proximity to scar during cardiac resynchronization therapy increases local dispersion of repolarization and susceptibility to ventricular arrhythmogenesis.

(2019) Caroline Mendonca Costa et al.   HEART RHYTHM

Generation of a cohort of whole-torso cardiac models for assessing the utility of a novel computed shock vector efficiency metric for ICD optimisation

(2019) Anne-Marie Plancke et al.   COMPUTERS IN BIOLOGY AND MEDICINE

Comprehensive Uncertainty Quantification and Sensitivity Analysis for Cardiac Action Potential Models

(2019) Pras Pathmanathan et al.   Frontiers in Physiology

Computationally guided personalized targeted ablation of persistent atrial fibrillation

(2019) Patrick M. Boyle et al.   Nature Biomedical Engineering

Ventricular arrhythmia risk prediction in repaired Tetralogy of Fallot using personalized computational cardiac models

(2019) Julie K. Shade et al.   HEART RHYTHM

A rule-based method for predicting the electrical activation of the heart with cardiac resynchronization therapy from non-invasive clinical data

(2019) A.W.C. Lee et al.   MEDICAL IMAGE ANALYSIS

A work flow to build and validate patient specific left atrium electrophysiology models from catheter measurements

(2018) Cesare Corrado et al.   MEDICAL IMAGE ANALYSIS

Personalized computational modeling of left atrial geometry and transmural myofiber architecture

(2018) Thomas E. Fastl et al.   MEDICAL IMAGE ANALYSIS

Patient-Specific Cardiovascular Computational Modeling: Diversity of Personalization and Challenges

(2018) Richard A. Gray et al.   Journal of Cardiovascular Translational Research

Validation and Trustworthiness of Multiscale Models of Cardiac Electrophysiology

(2018) Pras Pathmanathan et al.   Frontiers in Physiology

Personalized virtual-heart technology for guiding the ablation of infarct-related ventricular tachycardia

(2018) Adityo Prakosa et al.   Nature Biomedical Engineering

Patient-Specific Left Ventricular Flow Simulations From Transthoracic Echocardiography: Robustness Evaluation and Validation Against Ultrasound Doppler and Magnetic Resonance Imaging

(2017) David Larsson et al.   IEEE TRANSACTIONS ON MEDICAL IMAGING

Rotors exhibit greater surface ECG variation during ventricular fibrillation than focal sources due to wavebreak, secondary rotors, and meander

(2017) Gordon Ho et al.   JOURNAL OF CARDIOVASCULAR ELECTROPHYSIOLOGY

Efficient computation of electrograms and ECGs in human whole heart simulations using a reaction-eikonal model

(2017) Aurel Neic et al.   JOURNAL OF COMPUTATIONAL PHYSICS

A two-variable model robust to pacemaker behaviour for the dynamics of the cardiac action potential

(2016) Cesare Corrado et al.   MATHEMATICAL BIOSCIENCES

Arrhythmia risk stratification of patients after myocardial infarction using personalized heart models

(2016) Hermenegild J. Arevalo et al.   Nature Communications

Comparison of Detailed and Simplified Models of Human Atrial Myocytes to Recapitulate Patient Specific Properties

(2016) Daniel M. Lombardo et al.   PLoS Computational Biology

Towards Personalized Cardiology: Multi-Scale Modeling of the Failing Heart

(2015) Elham Kayvanpour et al.   PLoS One

Differences in quantitative assessment of myocardial scar and gray zone by LGE-CMR imaging using established gray zone protocols

(2014) Olurotimi Mesubi et al.   INTERNATIONAL JOURNAL OF CARDIOVASCULAR IMAGING

Verification of computational models of cardiac electro-physiology

(2013) Pras Pathmanathan et al.   International Journal for Numerical Methods in Biomedical Engineering

Chaste: An Open Source C++ Library for Computational Physiology and Biology

(2013) Gary R. Mirams et al.   PLoS Computational Biology

A Novel Rule-Based Algorithm for Assigning Myocardial Fiber Orientation to Computational Heart Models

(2012) J. D. Bayer et al.   ANNALS OF BIOMEDICAL ENGINEERING

How the Hodgkin-Huxley equations inspired the Cardiac Physiome Project

(2012) Denis Noble et al.   JOURNAL OF PHYSIOLOGY-LONDON

Representing Cardiac Bidomain Bath-Loading Effects by an Augmented Monodomain Approach: Application to Complex Ventricular Models

(2011) Martin J Bishop et al.   IEEE TRANSACTIONS ON BIOMEDICAL ENGINEERING

Patient-specific finite element analysis of the human femur—A double-blinded biomechanical validation

(2011) Nir Trabelsi et al.   JOURNAL OF BIOMECHANICS

Patient-specific electromechanical models of the heart for the prediction of pacing acute effects in CRT: A preliminary clinical validation

(2011) M. Sermesant et al.   MEDICAL IMAGE ANALYSIS

Verification of cardiac tissue electrophysiology simulators using an N-version benchmark

(2011) S. A. Niederer et al.   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY A-MATHEMATICAL PHYSICAL AND ENGINEERING SCIENCES

Simulation of the Undiseased Human Cardiac Ventricular Action Potential: Model Formulation and Experimental Validation

(2011) Thomas O'Hara et al.   PLoS Computational Biology

Models of cardiac tissue electrophysiology: Progress, challenges and open questions

(2010) R.H. Clayton et al.   PROGRESS IN BIOPHYSICS & MOLECULAR BIOLOGY

A novel computational model of the human ventricular action potential and Ca transient

(2009) Eleonora Grandi et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

The Virtual Family—development of surface-based anatomical models of two adults and two children for dosimetric simulations

(2009) Andreas Christ et al.   PHYSICS IN MEDICINE AND BIOLOGY