Patient-Specific Cardiovascular Computational Modeling: Diversity of Personalization and Challenges

Validation and Trustworthiness of Multiscale Models of Cardiac Electrophysiology

(2018) Pras Pathmanathan et al.   Frontiers in Physiology

Personalized Models of Human Atrial Electrophysiology Derived From Endocardial Electrograms

(2017) Cesare Corrado et al.   IEEE TRANSACTIONS ON BIOMEDICAL ENGINEERING

Noninvasive Personalization of a Cardiac Electrophysiology Model From Body Surface Potential Mapping

(2017) Sophie Giffard-Roisin et al.   IEEE TRANSACTIONS ON BIOMEDICAL ENGINEERING

An FDA Viewpoint on Unique Considerations for Medical-Device Clinical Trials

(2017) Owen Faris et al.   NEW ENGLAND JOURNAL OF MEDICINE

Towards Precision Medicine in the Clinic: From Biomarker Discovery to Novel Therapeutics

(2017) Dearbhaile C. Collins et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

The Virtual Physiological Human: Ten Years After

(2016) Marco Viceconti et al.   Annual Review of Biomedical Engineering

The relative role of patient physiology and device optimisation in cardiac resynchronisation therapy: A computational modelling study

(2016) Andrew Crozier et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Patient-specific modelling of abdominal aortic aneurysms: The influence of wall thickness on predicted clinical outcomes

(2016) Noel Conlisk et al.   MEDICAL ENGINEERING & PHYSICS

Precision medicine in cardiology

(2016) Elliott M. Antman et al.   Nature Reviews Cardiology

In vivo genome editing — growing in strength

(2016) Linda Koch   NATURE REVIEWS GENETICS

Translating Trial Results in Clinical Practice: the Risk GP Model

(2016) Jonathan Fuller et al.   Journal of Cardiovascular Translational Research

Arrhythmia risk stratification of patients after myocardial infarction using personalized heart models

(2016) Hermenegild J. Arevalo et al.   Nature Communications

Comparison of Detailed and Simplified Models of Human Atrial Myocytes to Recapitulate Patient Specific Properties

(2016) Daniel M. Lombardo et al.   PLoS Computational Biology

Personalized Computer Simulation of Diastolic Function in Heart Failure

(2016) Ali Amr et al.   GENOMICS PROTEOMICS & BIOINFORMATICS

Reducing the number of parameters in 1D arterial blood flow modeling: less is more for patient-specific simulations

(2015) Sally Epstein et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Personalized Cardiovascular Medicine Today

(2015) Alison Blaus et al.   CIRCULATION

Computational fluid dynamics modelling in cardiovascular medicine

(2015) Paul D Morris et al.   HEART

A New Initiative on Precision Medicine

(2015) Francis S. Collins et al.   NEW ENGLAND JOURNAL OF MEDICINE

Towards Personalized Cardiology: Multi-Scale Modeling of the Failing Heart

(2015) Elham Kayvanpour et al.   PLoS One

Uncertainty quantification of fast sodium current steady-state inactivation for multi-scale models of cardiac electrophysiology

(2015) Pras Pathmanathan et al.   PROGRESS IN BIOPHYSICS & MOLECULAR BIOLOGY

Noninvasive Fractional Flow Reserve Derived From Coronary CT Angiography

(2015) James K. Min et al.   JACC-Cardiovascular Imaging

Filament Dynamics during Simulated Ventricular Fibrillation in a High-Resolution Rabbit Heart

(2015) Pras Pathmanathan et al.   Biomed Research International

The continuum of personalized cardiovascular medicine: a position paper of the European Society of Cardiology

(2014) Paulus Kirchhof et al.   EUROPEAN HEART JOURNAL

The Living Heart Project: A robust and integrative simulator for human heart function

(2014) Brian Baillargeon et al.   EUROPEAN JOURNAL OF MECHANICS A-SOLIDS

Data-driven estimation of cardiac electrical diffusivity from 12-lead ECG signals

(2014) Oliver Zettinig et al.   MEDICAL IMAGE ANALYSIS

Noninvasive Electrocardiographic Imaging of Arrhythmogenic Substrates in Humans

(2013) Yoram Rudy   CIRCULATION RESEARCH

An integrated approach to patient-specific predictive modeling for single ventricle heart palliation

(2013) Chiara Corsini et al.   COMPUTER METHODS IN BIOMECHANICS AND BIOMEDICAL ENGINEERING

Evaluating strict and conventional left bundle branch block criteria using electrocardiographic simulations

(2013) L. Galeotti et al.   EUROPACE

Feasibility of image-based simulation to estimate ablation target in human ventricular arrhythmia

(2013) Hiroshi Ashikaga et al.   HEART RHYTHM

Verification of computational models of cardiac electro-physiology

(2013) Pras Pathmanathan et al.   International Journal for Numerical Methods in Biomedical Engineering

Computational Fluid Dynamics Applied to Cardiac Computed Tomography for Noninvasive Quantification of Fractional Flow Reserve

(2013) Charles A. Taylor et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

An automatic service for the personalization of ventricular cardiac meshes

(2013) P. Lamata et al.   Journal of the Royal Society Interface

Share and enjoy: anatomical models database—generating and sharing cardiovascular model data using web services

(2013) Eric Kerfoot et al.   MEDICAL & BIOLOGICAL ENGINEERING & COMPUTING

Ensuring reliability of safety-critical clinical applications of computational cardiac models

(2013) Pras Pathmanathan et al.   Frontiers in Physiology

Image-Based Estimation of Ventricular Fiber Orientations for Personalized Modeling of Cardiac Electrophysiology

(2012) F. Vadakkumpadan et al.   IEEE TRANSACTIONS ON MEDICAL IMAGING

Comparison of patient-specific inlet boundary conditions in the numerical modelling of blood flow in abdominal aortic aneurysm disease

(2012) David Hardman et al.   International Journal for Numerical Methods in Biomedical Engineering

Toward patient-specific simulations of cardiac valves: State-of-the-art and future directions

(2012) Emiliano Votta et al.   JOURNAL OF BIOMECHANICS

Patient-specific models of cardiac biomechanics

(2012) Adarsh Krishnamurthy et al.   JOURNAL OF COMPUTATIONAL PHYSICS

In Silico Cardiac Risk Assessment in Patients With Long QT Syndrome

(2012) Ryan Hoefen et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Preparing for Precision Medicine

(2012) Reza Mirnezami et al.   NEW ENGLAND JOURNAL OF MEDICINE

Investigating the Role of the Coronary Vasculature in the Mechanisms of Defibrillation

(2011) Martin J. Bishop et al.   Circulation-Arrhythmia and Electrophysiology

Patient-specific electromechanical models of the heart for the prediction of pacing acute effects in CRT: A preliminary clinical validation

(2011) M. Sermesant et al.   MEDICAL IMAGE ANALYSIS

Patient-specific modeling of dyssynchronous heart failure: A case study

(2011) Jazmin Aguado-Sierra et al.   PROGRESS IN BIOPHYSICS & MOLECULAR BIOLOGY

Coupled personalization of cardiac electrophysiology models for prediction of ischaemic ventricular tachycardia

(2011) J. Relan et al.   Interface Focus

euHeart: personalized and integrated cardiac care using patient-specific cardiovascular modelling

(2011) N. Smith et al.   Interface Focus

Cardiac Electromechanical Models: From Cell to Organ

(2011) Natalia A. Trayanova et al.   Frontiers in Physiology

Length-dependent tension in the failing heart and the efficacy of cardiac resynchronization therapy

(2010) Steven A. Niederer et al.   CARDIOVASCULAR RESEARCH

Patient-Specific Modeling of Cardiovascular Mechanics

(2009) C.A. Taylor et al.   Annual Review of Biomedical Engineering

Coupling multi-physics models to cardiac mechanics

(2009) D.A. Nordsletten et al.   PROGRESS IN BIOPHYSICS & MOLECULAR BIOLOGY

A guide to modelling cardiac electrical activity in anatomically detailed ventricles

(2007) R.H. Clayton et al.   PROGRESS IN BIOPHYSICS & MOLECULAR BIOLOGY