Deep transfer learning of cancer drug responses by integrating bulk and single-cell RNA-seq data
Published 2022 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Deep transfer learning of cancer drug responses by integrating bulk and single-cell RNA-seq data
Authors
Keywords
-
Journal
Nature Communications
Volume 13, Issue 1, Pages -
Publisher
Springer Science and Business Media LLC
Online
2022-10-30
DOI
10.1038/s41467-022-34277-7
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Deep learning shapes single-cell data analysis
- (2022) Qin Ma et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Variant calling from scRNA-seq data allows the assessment of cellular identity in patient-derived cell lines
- (2022) Daniele Ramazzotti et al. Nature Communications
- Joint probabilistic modeling of single-cell multi-omic data with totalVI
- (2021) Adam Gayoso et al. NATURE METHODS
- Single-cell transcriptional changes associated with drug tolerance and response to combination therapies in cancer
- (2021) Alexandre F. Aissa et al. Nature Communications
- scGNN is a novel graph neural network framework for single-cell RNA-Seq analyses
- (2021) Juexin Wang et al. Nature Communications
- Tumor hypoxia: The major culprit behind cisplatin resistance in cancer patients
- (2021) Nalini Devarajan et al. CRITICAL REVIEWS IN ONCOLOGY HEMATOLOGY
- Inhibition of USP28 overcomes Cisplatin-resistance of squamous tumors by suppression of the Fanconi anemia pathway
- (2021) Cristian Prieto-Garcia et al. CELL DEATH AND DIFFERENTIATION
- Single-Cell Transcriptomics Analysis Identifies Nuclear Protein 1 as a Regulator of Docetaxel Resistance in Prostate Cancer Cells
- (2020) Patricia M. Schnepp et al. MOLECULAR CANCER RESEARCH
- Single-Cell Techniques and Deep Learning in Predicting Drug Response
- (2020) Zhenyu Wu et al. TRENDS IN PHARMACOLOGICAL SCIENCES
- The single-cell transcriptional landscape of mammalian organogenesis
- (2019) Junyue Cao et al. NATURE
- A PolH transcript with a short 3'UTR enhances PolH expression and mediates cisplatin resistance
- (2019) Jin Zhang et al. CANCER RESEARCH
- Targeting enhancer switching overcomes non-genetic drug resistance in acute myeloid leukaemia
- (2019) Charles C. Bell et al. Nature Communications
- Data denoising with transfer learning in single-cell transcriptomics
- (2019) Jingshu Wang et al. NATURE METHODS
- Estimation of clinical trial success rates and related parameters
- (2018) Chi Heem Wong et al. BIOSTATISTICS
- Toward Minimal Residual Disease-Directed Therapy in Melanoma
- (2018) Florian Rambow et al. CELL
- Application of transfer learning for cancer drug sensitivity prediction
- (2018) Saugato Rahman Dhruba et al. BMC BIOINFORMATICS
- Concurrent Single-Cell RNA and Targeted DNA Sequencing on an Automated Platform for Comeasurement of Genomic and Transcriptomic Signatures
- (2018) Say Li Kong et al. CLINICAL CHEMISTRY
- Longitudinal single-cell RNA sequencing of patient-derived primary cells reveals drug-induced infidelity in stem cell hierarchy
- (2018) Ankur Sharma et al. Nature Communications
- Three-dimensional cell culture models for anticancer drug screening: Worth the effort?
- (2017) Eddy-Tim Verjans et al. JOURNAL OF CELLULAR PHYSIOLOGY
- A Landscape of Pharmacogenomic Interactions in Cancer
- (2016) Francesco Iorio et al. CELL
- Perturb-Seq: Dissecting Molecular Circuits with Scalable Single-Cell RNA Profiling of Pooled Genetic Screens
- (2016) Atray Dixit et al. CELL
- Identifying compound efficacy targets in phenotypic drug discovery
- (2016) Markus Schirle et al. DRUG DISCOVERY TODAY
- The functional status of DNA repair pathways determines the sensitization effect to cisplatin in non-small cell lung cancer cells
- (2016) Ping Chen et al. CELLULAR ONCOLOGY
- DKK1 is a potential novel mediator of cisplatin-refractoriness in non-small cell lung cancer cell lines
- (2015) Hogir Salim et al. BMC CANCER
- Kremen1 and Dickkopf1 control cell survival in a Wnt-independent manner
- (2015) F Causeret et al. CELL DEATH AND DIFFERENTIATION
- Role of mismatch repair proteins in the processing of cisplatin interstrand cross-links
- (2015) Akshada Sawant et al. DNA REPAIR
- Cyclin F suppresses B-Myb activity to promote cell cycle checkpoint control
- (2015) Ditte Kjærsgaard Klein et al. Nature Communications
- Cisplatin in cancer therapy: Molecular mechanisms of action
- (2014) Shaloam Dasari et al. EUROPEAN JOURNAL OF PHARMACOLOGY
- FOXM1 Modulates Cisplatin Sensitivity by Regulating EXO1 in Ovarian Cancer
- (2014) Jinhua Zhou et al. PLoS One
- A Small-Molecule Inhibitor of RAD51 Reduces Homologous Recombination and Sensitizes Multiple Myeloma Cells to Doxorubicin
- (2014) David A. Alagpulinsa et al. Frontiers in Oncology
- The Cancer Cell Line Encyclopedia enables predictive modelling of anticancer drug sensitivity
- (2012) Jordi Barretina et al. NATURE
- Genomics of Drug Sensitivity in Cancer (GDSC): a resource for therapeutic biomarker discovery in cancer cells
- (2012) Wanjuan Yang et al. NUCLEIC ACIDS RESEARCH
- Error-prone translesion synthesis mediates acquired chemoresistance
- (2010) K. Xie et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- BUB1 and BUBR1: multifaceted kinases of the cell cycle
- (2010) Victor M. Bolanos-Garcia et al. TRENDS IN BIOCHEMICAL SCIENCES
- Oncogenes and Tumor Suppressor Genes
- (2010) E. Y. H. P. Lee et al. Cold Spring Harbor Perspectives in Biology
- How the Fanconi Anemia Pathway Guards the Genome
- (2009) George-Lucian Moldovan et al. Annual Review of Genetics
- A Survey on Transfer Learning
- (2009) Sinno Jialin Pan et al. IEEE TRANSACTIONS ON KNOWLEDGE AND DATA ENGINEERING
- Homologous recombination in DNA repair and DNA damage tolerance
- (2008) Xuan Li et al. CELL RESEARCH
- Mitotic checkpoint defects in human cancers and their implications to chemotherapy
- (2007) Xianghong Wang Frontiers in Bioscience-Landmark
Publish scientific posters with Peeref
Peeref publishes scientific posters from all research disciplines. Our Diamond Open Access policy means free access to content and no publication fees for authors.
Learn MoreFind the ideal target journal for your manuscript
Explore over 38,000 international journals covering a vast array of academic fields.
Search