The functional status of DNA repair pathways determines the sensitization effect to cisplatin in non-small cell lung cancer cells

Interplay between Fanconi anemia and homologous recombination pathways in genome integrity

(2016) Johanna Michl et al.   EMBO JOURNAL

Expression of the microRNA regulators Drosha, Dicer and Ago2 in non-small cell lung carcinomas

(2015) E. Prodromaki et al.   CELLULAR ONCOLOGY

RRM1 expression is associated with the outcome of gemcitabine-based treatment of non-small cell lung cancer patients–a short report

(2015) Chuan Zeng et al.   CELLULAR ONCOLOGY

Anti-proliferative, apoptotic and signal transduction effects of hesperidin in non-small cell lung cancer cells

(2015) Zeynep Birsu Cincin et al.   CELLULAR ONCOLOGY

Mouse SLX4 Is a Tumor Suppressor that Stimulates the Activity of the Nuclease XPF-ERCC1 in DNA Crosslink Repair

(2014) Michael R.G. Hodskinson et al.   MOLECULAR CELL

Curcumin reverses cisplatin resistance in cisplatin-resistant lung caner cells by inhibiting FA/BRCA pathway

(2014) Ping Chen et al.   TUMOR BIOLOGY

The chemosensitivity of testicular germ cell tumors

(2014) Ioannis A. Voutsadakis   CELLULAR ONCOLOGY

Epidermal growth factor receptor mutations in East European non-small cell lung cancer patients

(2014) Stoyan Naidenov Bichev et al.   CELLULAR ONCOLOGY

Modularized Functions of the Fanconi Anemia Core Complex

(2014) Yaling Huang et al.   Cell Reports

Fanconi Anemia Repair Pathway Dysfunction, a Potential Therapeutic Target in Lung Cancer

(2014) Wenrui Duan et al.   Frontiers in Oncology

Regulation of DNA cross-link repair by the Fanconi anemia/BRCA pathway

(2012) H. Kim et al.   GENES & DEVELOPMENT

Reduced Proficiency in Homologous Recombination Underlies the High Sensitivity of Embryonal Carcinoma Testicular Germ Cell Tumors to Cisplatin and Poly (ADP-Ribose) Polymerase Inhibition

(2012) Francesca Cavallo et al.   PLoS One

The E3 ubiquitin ligase RAD18 regulates ubiquitylation and chromatin loading of FANCD2 and FANCI

(2011) S. A. Williams et al.   BLOOD

Selective and Cell-Active Inhibitors of the USP1/ UAF1 Deubiquitinase Complex Reverse Cisplatin Resistance in Non-small Cell Lung Cancer Cells

(2011) Junjun Chen et al.   CHEMISTRY & BIOLOGY

Molecular mechanisms of cisplatin resistance

(2011) L Galluzzi et al.   ONCOGENE

Mechanism of RAD51-Dependent DNA Interstrand Cross-Link Repair

(2011) D. T. Long et al.   SCIENCE

The Epistatic Relationship between BRCA2 and the Other RAD51 Mediators in Homologous Recombination

(2011) Yong Qing et al.   PLoS Genetics

Downregulation of XPF–ERCC1 enhances cisplatin efficacy in cancer cells☆

(2010) Sanjeevani Arora et al.   DNA REPAIR

Genetic profiling and epidermal growth factor receptor-directed therapy in nonsmall cell lung cancer

(2010) J. Cadranel et al.   EUROPEAN RESPIRATORY JOURNAL

Expanded roles of the Fanconi anemia pathway in preserving genomic stability

(2010) Y. Kee et al.   GENES & DEVELOPMENT

Cisplatin sensitivity of testis tumour cells is due to deficiency in interstrand-crosslink repair and low ERCC1-XPF expression

(2010) Svetlana Usanova et al.   Molecular Cancer

Maintaining genome stability at the replication fork

(2010) Dana Branzei et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

A new nuclease member of the FAN club

(2010) Min Huang et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

The XPA-binding domain of ERCC1 Is Required for Nucleotide Excision Repair but Not Other DNA Repair Pathways

(2009) Barbara Orelli et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

XPF-ERCC1 Participates in the Fanconi Anemia Pathway of Cross-Link Repair

(2009) N. Bhagwat et al.   MOLECULAR AND CELLULAR BIOLOGY

RAD18 transmits DNA damage signalling to elicit homologous recombination repair

(2009) Jun Huang et al.   NATURE CELL BIOLOGY

Mechanism of Eukaryotic Homologous Recombination

(2008) Joseph San Filippo et al.   Annual Review of Biochemistry

Structural and Functional Relationships of the XPF/MUS81 Family of Proteins

(2008) Alberto Ciccia et al.   Annual Review of Biochemistry

Histone H2AX phosphorylation as a molecular pharmacological marker for DNA interstrand crosslink cancer chemotherapy

(2008) P.H. Clingen et al.   BIOCHEMICAL PHARMACOLOGY

Mechanism of Replication-Coupled DNA Interstrand Crosslink Repair

(2008) Markus Räschle et al.   CELL

Homologous recombination in DNA repair and DNA damage tolerance

(2008) Xuan Li et al.   CELL RESEARCH

Phenylbutyrate interferes with the Fanconi anemia and BRCA pathway and sensitizes head and neck cancer cells to cisplatin

(2008) Kyunghee Burkitt et al.   Molecular Cancer