Glenzocimab: A GPVI (Glycoprotein VI)-Targeted Potential Antiplatelet Agent for the Treatment of Acute Ischemic Stroke
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Title
Glenzocimab: A GPVI (Glycoprotein VI)-Targeted Potential Antiplatelet Agent for the Treatment of Acute Ischemic Stroke
Authors
Keywords
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Journal
STROKE
Volume 53, Issue 11, Pages 3506-3513
Publisher
Ovid Technologies (Wolters Kluwer Health)
Online
2022-09-21
DOI
10.1161/strokeaha.122.039790
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Note: Only part of the references are listed.- Platelet surface receptor glycoprotein VI-dimer is overexpressed in stroke: The Glycoprotein VI in Stroke (GYPSIE) study results
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- (2021) Michael Bieber et al. EXPERIMENTAL NEUROLOGY
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- (2020) Muhammad Usman Ahmed et al. ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY
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- Targeting Platelet GPVI Plus rt-PA Administration but Not α2β1-Mediated Collagen Binding Protects against Ischemic Brain Damage in Mice
- (2019) Michael K. Schuhmann et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Transfusion of Resting Platelets Reduces Brain Hemorrhage After Intracerebral Hemorrhage and tPA-Induced Hemorrhage After Cerebral Ischemia
- (2019) Haiyu Luo et al. Frontiers in Neuroscience
- Guidelines for the Early Management of Patients With Acute Ischemic Stroke: 2019 Update to the 2018 Guidelines for the Early Management of Acute Ischemic Stroke: A Guideline for Healthcare Professionals From the American Heart Association/American Stroke Association
- (2019) William J. Powers et al. STROKE
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- (2018) Steven P. Grover et al. ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY
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- Platelet Signaling and Disease: Targeted Therapy for Thrombosis and Other Related Diseases
- (2018) Jennifer Yeung et al. PHARMACOLOGICAL REVIEWS
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- (2018) José Carlos Rodríguez-Jiménez et al. RESPIRATORY MEDICINE
- The contribution of platelet glycoprotein receptors to inflammatory bleeding prevention is stimulus and organ dependent
- (2018) Julie Rayes et al. HAEMATOLOGICA
- GPVI and Thromboxane Receptor on Platelets Promote Proinflammatory Macrophage Phenotypes during Cutaneous Inflammation
- (2017) Sandra Pierre et al. JOURNAL OF INVESTIGATIVE DERMATOLOGY
- Design, development and characterization of ACT017, a humanized Fab that blocks platelet's glycoprotein VI function without causing bleeding risks
- (2017) Kristell Lebozec et al. mAbs
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- (2016) Christina Pachel et al. ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY
- Platelets are versatile cells: New discoveries in hemostasis, thrombosis, immune responses, tumor metastasis and beyond
- (2016) Xiaohong Ruby Xu et al. CRITICAL REVIEWS IN CLINICAL LABORATORY SCIENCES
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- (2016) Gang Du et al. INTERNATIONAL JOURNAL OF CARDIOLOGY
- Differential Inhibition of Human Atherosclerotic Plaque–Induced Platelet Activation by Dimeric GPVI-Fc and Anti-GPVI Antibodies
- (2015) Janina Jamasbi et al. JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY
- Combined In Vivo Depletion of Glycoprotein VI and C-Type Lectin-Like Receptor 2 Severely Compromises Hemostasis and Abrogates Arterial Thrombosis in Mice
- (2013) Markus Bender et al. ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY
- Gastrointestinal Adverse Events after Dual Antiplatelet Therapy: Clopidogrel Is Safer than Ticagrelor, but Prasugrel Data Are Lacking or Inconclusive
- (2013) Victor L. Serebruany et al. CARDIOLOGY
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- (2013) Yacine Boulaftali et al. JOURNAL OF CLINICAL INVESTIGATION
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- (2009) L. Wallentin EUROPEAN HEART JOURNAL
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- (2008) P. OHLMANN et al. JOURNAL OF THROMBOSIS AND HAEMOSTASIS
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