Pharmacological Blockade of GPVI Promotes Thrombus Disaggregation in the Absence of Thrombin

Immobilized fibrinogen activates human platelets through glycoprotein VI

(2018) Pierre H Mangin et al.   HAEMATOLOGICA

Immobilized fibrinogen activates human platelets through glycoprotein VI

(2018) Pierre H Mangin et al.   HAEMATOLOGICA

Design, development and characterization of ACT017, a humanized Fab that blocks platelet's glycoprotein VI function without causing bleeding risks

(2017) Kristell Lebozec et al.   mAbs

Platelet Control of Fibrin Distribution and Microelasticity in Thrombus Formation Under FlowSignificance

(2016) Frauke Swieringa et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Rupture Forces among Human Blood Platelets at different Degrees of Activation

(2016) Thi-Huong Nguyen et al.   Scientific Reports

Platelet glycoprotein VI binds to polymerized fibrin and promotes thrombin generation

(2015) E. Mammadova-Bach et al.   BLOOD

Fibrin activates GPVI in human and mouse platelets

(2015) O. M. Alshehri et al.   BLOOD

Differential Inhibition of Human Atherosclerotic Plaque–Induced Platelet Activation by Dimeric GPVI-Fc and Anti-GPVI Antibodies

(2015) Janina Jamasbi et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Fibrillar cellular fibronectin supports efficient platelet aggregation and procoagulant activity

(2015) Eric Maurer et al.   THROMBOSIS AND HAEMOSTASIS

A systems approach to hemostasis: 1. The interdependence of thrombus architecture and agonist movements in the gaps between platelets

(2014) J. D. Welsh et al.   BLOOD

Integrin α 6 β 1 Is the Main Receptor for Vascular Laminins and Plays a Role in Platelet Adhesion, Activation, and Arterial Thrombosis

(2013) Mathieu Schaff et al.   CIRCULATION

An adenine insertion in exon 6 of humanGP6generates a truncated protein associated with a bleeding disorder in four Chilean families

(2013) V. Matus et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

New Fundamentals in Hemostasis

(2013) Henri H. Versteeg et al.   PHYSIOLOGICAL REVIEWS

The future of glycoprotein VI as an antithrombotic target

(2012) M. ZAHID et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

GPIbα-vWF Rolling under Shear Stress Shows Differences between Type 2B and 2M von Willebrand Disease

(2011) L.A. Coburn et al.   BIOPHYSICAL JOURNAL

Novel Antiplatelet Drug Revacept (Dimeric Glycoprotein VI-Fc) Specifically and Efficiently Inhibited Collagen-Induced Platelet Aggregation Without Affecting General Hemostasis in Humans

(2011) Martin Ungerer et al.   CIRCULATION

Genetic and antibody-induced glycoprotein VI deficiency equally protects mice from mechanically and FeCl3-induced thrombosis

(2011) M. BENDER et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Arterial thrombosis—insidious, unpredictable and deadly

(2011) Shaun P Jackson   NATURE MEDICINE

Absence of collagen-induced platelet activation caused by compound heterozygous GPVI mutations

(2009) B. Dumont et al.   BLOOD

Afibrinogenemia resulting from homozygous nonsense mutation in A alpha chain gene associated with multiple thrombotic episodes

(2009) Ismail Simsek et al.   BLOOD COAGULATION & FIBRINOLYSIS

A compound heterozygous mutation in glycoprotein VI in a patient with a bleeding disorder

(2009) C. HERMANS et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Arterial thrombosis: relevance of a model with two levels of severity assessed by histologic, ultrastructural and functional characterization

(2009) B. HECHLER et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Complementary roles of platelets and coagulation in thrombus formation on plaques acutely ruptured by targeted ultrasound treatment: a novel intravital model

(2008) M. J. E. KUIJPERS et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS