ApoE knockout and knockin mice: the history of their contribution to the understanding of atherogenesis

Beyond vascular inflammation—recent advances in understanding atherosclerosis

(2015) Dennis Wolf et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Apolipoprotein E Enhances MicroRNA-146a in Monocytes and Macrophages to Suppress Nuclear Factor- B-Driven Inflammation and Atherosclerosis

(2015) K. Li et al.   CIRCULATION RESEARCH

Proteomic analysis of HDL from inbred mouse strains implicates APOE associated with HDL in reduced cholesterol efflux capacity via the ABCA1 pathway

(2015) Nathalie Pamir et al.   JOURNAL OF LIPID RESEARCH

Identification of Aortic Arch-Specific Quantitative Trait Loci for Atherosclerosis by an Intercross of DBA/2J and 129S6 Apolipoprotein E-Deficient Mice

(2015) Yukako Kayashima et al.   PLoS One

Apolipoprotein E isoforms and lipoprotein metabolism

(2014) Michael C. Phillips   IUBMB LIFE

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(2014) Göran Hansson   MOLECULAR MEDICINE

Apolipoprotein E: Structure and function in lipid metabolism, neurobiology, and Alzheimer's diseases

(2014) Yadong Huang et al.   NEUROBIOLOGY OF DISEASE

Quantitative Trait Loci Affecting Atherosclerosis at the Aortic Root Identified in an Intercross between DBA2J and 129S6 Apolipoprotein E-Null Mice

(2014) Yukako Kayashima et al.   PLoS One

Effects of the Absence of Apolipoprotein E on Lipoproteins, Neurocognitive Function, and Retinal Function

(2014) Angel C. Y. Mak et al.   JAMA Neurology

Molecular Mechanisms Responsible for the Differential Effects of ApoE3 and ApoE4 on Plasma Lipoprotein–Cholesterol Levels

(2013) Hui Li et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Inducible Apoe Gene Repair in Hypomorphic ApoE Mice Deficient in the Low-Density Lipoprotein Receptor Promotes Atheroma Stabilization with a Human-Like Lipoprotein Profile

(2013) Delphine Eberlé et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Altered Expression of Raet1e , a Major Histocompatibility Complex Class 1–Like Molecule, Underlies the Atherosclerosis Modifier Locus Ath11 10b

(2013) José M. Rodríguez et al.   CIRCULATION RESEARCH

Genetics of Common Forms of Heart Disease

(2013) Carrie Welch et al.   CIRCULATION RESEARCH

Adaptive immunity in atherogenesis: new insights and therapeutic approaches

(2013) Andrew H. Lichtman et al.   JOURNAL OF CLINICAL INVESTIGATION

Molecular Biology of Atherosclerosis

(2013) Paul N. Hopkins   PHYSIOLOGICAL REVIEWS

Transcriptome Analysis of Genes Regulated by Cholesterol Loading in Two Strains of Mouse Macrophages Associates Lysosome Pathway and ER Stress Response with Atherosclerosis Susceptibility

(2013) Stela Z. Berisha et al.   PLoS One

Animal Models of Atherosclerosis

(2012) Godfrey S. Getz et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Apolipoprotein E4 Domain Interaction Accelerates Diet-Induced Atherosclerosis in Hypomorphic Arg-61 Apoe Mice

(2012) Delphine Eberlé et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Genetic Basis of Atherosclerosis: Insights From Mice and Humans

(2012) Ioannis M. Stylianou et al.   CIRCULATION RESEARCH

Apolipoprotein E Enhances Endothelial-NO Production by Modulating Caveolin 1 Interaction With Endothelial NO Synthase

(2012) Lili Yue et al.   HYPERTENSION

Macrophage-Specific ApoE Gene Repair Reduces Diet-Induced Hyperlipidemia and Atherosclerosis in Hypomorphic Apoe Mice

(2012) Nathalie Gaudreault et al.   PLoS One

Apolipoprotein E Induces Antiinflammatory Phenotype in Macrophages

(2011) Daniel Baitsch et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Development of Apolipoprotein E–Deficient Mice

(2011) Nobuyo Maeda   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

ApoE Suppresses Atherosclerosis by Reducing Lipid Accumulation in Circulating Monocytes and the Expression of Inflammatory Molecules on Monocytes and Vascular Endothelium

(2011) Nathalie Gaudreault et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Apolipoprotein E4 Exaggerates Diabetic Dyslipidemia and Atherosclerosis in Mice Lacking the LDL Receptor

(2011) L. A. Johnson et al.   DIABETES

ApoE regulates hematopoietic stem cell proliferation, monocytosis, and monocyte accumulation in atherosclerotic lesions in mice

(2011) Andrew J. Murphy et al.   JOURNAL OF CLINICAL INVESTIGATION

Macrophage, But Not Systemic, Apolipoprotein E Is Necessary for Macrophage Reverse Cholesterol Transport In Vivo

(2010) Ilaria Zanotti et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Apolipoprotein E inhibits Toll-like receptor (TLR)-3- and TLR-4-mediated macrophage activation through distinct mechanisms

(2010) Yanjuan Zhu et al.   BIOCHEMICAL JOURNAL

Aortic Arch Curvature and Atherosclerosis Have Overlapping Quantitative Trait Loci in a Cross Between 129S6/SvEvTac and C57BL/6J Apolipoprotein E–Null Mice

(2010) Hirofumi Tomita et al.   CIRCULATION RESEARCH

The Fat-Fed Apolipoprotein E Knockout Mouse Brachiocephalic Artery in the Study of Atherosclerotic Plaque Rupture

(2010) Andrew R. Bond et al.   JOURNAL OF BIOMEDICINE AND BIOTECHNOLOGY

Human LDL Receptor Enhances Sequestration of ApoE4 and VLDL Remnants on the Surface of Hepatocytes but Not Their Internalization in Mice

(2008) Michael Altenburg et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Intimal Hyperplasia in Murine Models

(2008) David Hui   CURRENT DRUG TARGETS

Apoprotein E as a lipid transport and signaling protein in the blood, liver, and artery wall

(2008) Godfrey S. Getz et al.   JOURNAL OF LIPID RESEARCH

Apolipoprotein E knock-out and knock-in mice: atherosclerosis, metabolic syndrome, and beyond: Fig. 1.

(2008) Avani A. Pendse et al.   JOURNAL OF LIPID RESEARCH

Apolipoprotein E: structure determines function, from atherosclerosis to Alzheimer's disease to AIDS

(2008) Robert W. Mahley et al.   JOURNAL OF LIPID RESEARCH