SIRT3-Mediated CypD-K166 Deacetylation Alleviates Neuropathic Pain by Improving Mitochondrial Dysfunction and Inhibiting Oxidative Stress

Targeting the Mitochondrial Permeability Transition Pore to Prevent Age-Associated Cell Damage and Neurodegeneration

(2021) Andrew C. Kent et al.   Oxidative Medicine and Cellular Longevity

The mitochondrial permeability transition pore: an evolving concept critical for cell life and death

(2021) Giampaolo Morciano et al.   BIOLOGICAL REVIEWS

Schisandrin B Antagonizes Cardiotoxicity Induced by Pirarubicin by Inhibiting Mitochondrial Permeability Transition Pore (mPTP) Opening and Decreasing Cardiomyocyte Apoptosis

(2021) Hongwei Shi et al.   Frontiers in Pharmacology

Mitoquinone alleviates vincristine-induced neuropathic pain through inhibiting oxidative stress and apoptosis via the improvement of mitochondrial dysfunction

(2020) Xue-Jun Chen et al.   BIOMEDICINE & PHARMACOTHERAPY

Neuropathic Pain: the Dysfunction of Drp1, Mitochondria, and ROS Homeostasis

(2020) Chun-Qiu Dai et al.   NEUROTOXICITY RESEARCH

Stem Cells in the Treatment of Neuropathic Pain: Research Progress of Mechanism

(2020) Meichen Liu et al.   Stem Cells International

Crosstalk between mitochondrial hyperacetylation and oxidative stress in vascular dysfunction and hypertension

(2019) Sergey I Dikalov et al.   ANTIOXIDANTS & REDOX SIGNALING

Dysregulation of p53 and Parkin Induce Mitochondrial Dysfunction and Leads to the Diabetic Neuropathic Pain

(2019) Ayahiro Yamashita et al.   NEUROSCIENCE

Alterations of Transcription of Genes Coding Anti-oxidative and Mitochondria-Related Proteins in Amyloid β Toxicity: Relevance to Alzheimer’s Disease

(2019) Magdalena Cieślik et al.   MOLECULAR NEUROBIOLOGY

The Mitochondrial Acylome Emerges: Proteomics, Regulation by Sirtuins, and Metabolic and Disease Implications

(2018) Chris Carrico et al.   Cell Metabolism

Epigenetics of pain mediators

(2018) Daniel W. Odell   Current Opinion in Anesthesiology

Protective effect of SIRT3 on acute lung injury by increasing manganese superoxide dismutase-mediated antioxidation

(2018) Yong Tian et al.   Molecular Medicine Reports

Neuropathic pain: Definition, assessment and epidemiology

(2018) D. Bouhassira   REVUE NEUROLOGIQUE

Crosstalk of mitochondria with NADPH oxidase via reactive oxygen and nitrogen species signalling and its role for vascular function

(2016) Andreas Daiber et al.   BRITISH JOURNAL OF PHARMACOLOGY

The role of mitochondrial sirtuins in health and disease

(2016) Brenna Osborne et al.   FREE RADICAL BIOLOGY AND MEDICINE

Regulation of the mPTP by SIRT3-mediated deacetylation of CypD at lysine 166 suppresses age-related cardiac hypertrophy

(2016) Angela V. Hafner et al.   Aging-US

Sirtuins in vascular diseases: Emerging roles and therapeutic potential

(2015) Nunzia D'Onofrio et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Inhibition of myocardial reperfusion injury by ischemic postconditioning requires sirtuin 3-mediated deacetylation of cyclophilin D

(2015) T. Bochaton et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Sirtuin 3 regulates Foxo3a-mediated antioxidant pathway in microglia

(2015) P. Rangarajan et al.   NEUROSCIENCE

The Mitochondrial Permeability Transition Pore: Channel Formation by F-ATP Synthase, Integration in Signal Transduction, and Role in Pathophysiology

(2015) Paolo Bernardi et al.   PHYSIOLOGICAL REVIEWS

Mitochondrial Reactive Oxygen Species (ROS) and ROS-Induced ROS Release

(2014) Dmitry B. Zorov et al.   PHYSIOLOGICAL REVIEWS

Spinal SIRT1 Activation Attenuates Neuropathic Pain in Mice

(2014) Haijun Shao et al.   PLoS One

Inhibition of cyclophilin D by cyclosporin A promotes retinal ganglion cell survival by preventing mitochondrial alteration in ischemic injury

(2014) S Y Kim et al.   Cell Death & Disease

Reactive oxygen species contribute to neuropathic pain and locomotor dysfunction via activation of CamKII in remote segments following spinal cord contusion injury in rats

(2013) Young S. Gwak et al.   PAIN

Two independent pathways of regulated necrosis mediate ischemia-reperfusion injury

(2013) A. Linkermann et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

SIRT3 regulation of mitochondrial oxidative stress

(2012) Alexandra S. Bause et al.   EXPERIMENTAL GERONTOLOGY

Effects of Oxidative Alcohol Metabolism on the Mitochondrial Permeability Transition Pore and Necrosis in a Mouse Model of Alcoholic Pancreatitis

(2012) Natalia Shalbueva et al.   GASTROENTEROLOGY

Sirt3, Mitochondrial ROS, Ageing, and Carcinogenesis

(2011) Seong-Hoon Park et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Epigenetic suppression of GAD65 expression mediates persistent pain

(2011) Zhi Zhang et al.   NATURE MEDICINE

Reactive oxygen species contribute to neuropathic pain by reducing spinal GABA release

(2011) June Yowtak et al.   PAIN

Redox signaling (cross-talk) from and to mitochondria involves mitochondrial pores and reactive oxygen species

(2010) Andreas Daiber   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

SIRT3 regulates mitochondrial fatty-acid oxidation by reversible enzyme deacetylation

(2010) Matthew D. Hirschey et al.   NATURE

Antimycin A and lipopolysaccharide cause the leakage of superoxide radicals from rat liver mitochondria

(2008) Christina Piskernik et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Edaravone, a free radical scavenger, is effective on neuropathic pain in rats

(2008) Yan-Fei Mao et al.   BRAIN RESEARCH