TAAR1 dependent and independent actions of the potential antipsychotic and dual TAAR1/5-HT1A receptor agonist SEP-383856
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Title
TAAR1 dependent and independent actions of the potential antipsychotic and dual TAAR1/5-HT1A receptor agonist SEP-383856
Authors
Keywords
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Journal
NEUROPSYCHOPHARMACOLOGY
Volume 47, Issue 13, Pages 2319-2329
Publisher
Springer Science and Business Media LLC
Online
2022-09-13
DOI
10.1038/s41386-022-01421-2
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- (2021) Ioannis Mantas et al. MOLECULAR PSYCHIATRY
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- (2021) Maria Qatato et al. Cells
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- (2021) Nina Dedic et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- The G protein database, GproteinDb
- (2021) Gáspár Pándy-Szekeres et al. NUCLEIC ACIDS RESEARCH
- Ulotaront: A TAAR1 Agonist for the Treatment of Schizophrenia
- (2021) Michele L. R. Heffernan et al. ACS Medicinal Chemistry Letters
- Safety and effectiveness of ulotaront (SEP-363856) in schizophrenia: results of a 6-month, open-label extension study
- (2021) Christoph U. Correll et al. npj Schizophrenia
- A Non–D2-Receptor-Binding Drug for the Treatment of Schizophrenia
- (2020) Kenneth S. Koblan et al. NEW ENGLAND JOURNAL OF MEDICINE
- Low intrinsic efficacy for G protein activation can explain the improved side effect profiles of new opioid agonists
- (2020) Alexander Gillis et al. Science Signaling
- Trace Amine-Associated Receptor 1 (TAAR1): A new drug target for psychiatry?
- (2020) Seetal Dodd et al. NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS
- Location Bias as Emerging Paradigm in GPCR Biology and Drug Discovery
- (2020) Mohammad Ali Mohammad Nezhady et al. iScience
- TAAR1 dependent and independent actions of tyramine in interaction with glutamate underlie central effects of monoamine oxidase inhibition
- (2020) Ioannis Mantas et al. BIOLOGICAL PSYCHIATRY
- Illuminating G-Protein-Coupling Selectivity of GPCRs
- (2019) Asuka Inoue et al. CELL
- SEP-363856, A NOVEL PSYCHOTROPIC AGENT WITH A UNIQUE, NON-D2 RECEPTOR MECHANISM OF ACTION
- (2019) Nina Dedic et al. JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS
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- (2019) Suzanne M. Underhill et al. MOLECULAR PSYCHIATRY
- Mini G protein probes for active G protein–coupled receptors (GPCRs) in live cells
- (2018) Qingwen Wan et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Trace Amines and Their Receptors
- (2018) Raul R. Gainetdinov et al. PHARMACOLOGICAL REVIEWS
- Global Epidemiology and Burden of Schizophrenia: Findings From the Global Burden of Disease Study 2016
- (2018) Fiona J Charlson et al. SCHIZOPHRENIA BULLETIN
- Management of common adverse effects of antipsychotic medications
- (2018) T. Scott Stroup et al. World Psychiatry
- Increased context-dependent conditioning to amphetamine in mice lacking TAAR1
- (2016) Ilya Sukhanov et al. PHARMACOLOGICAL RESEARCH
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- (2015) Tarsis F. Brust et al. BIOCHEMICAL PHARMACOLOGY
- Learning from the past and looking to the future: Emerging perspectives for improving the treatment of psychiatric disorders
- (2015) Mark J. Millan et al. EUROPEAN NEUROPSYCHOPHARMACOLOGY
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- (2015) A. Alvarsson et al. JOURNAL OF NEUROSCIENCE
- TAAR1 Modulates Cortical Glutamate NMDA Receptor Function
- (2015) Stefano Espinoza et al. NEUROPSYCHOPHARMACOLOGY
- Tissue-based map of the human proteome
- (2015) M. Uhlen et al. SCIENCE
- History of the Discovery of the Antipsychotic Dopamine D2 Receptor: A Basis for the Dopamine Hypothesis of Schizophrenia
- (2013) Bertha K. Madras Journal of the History of the Neurosciences
- Membrane permeability of trace amines: Evidence for a regulated, activity-dependent, nonexocytotic, synaptic release
- (2013) Mark D. Berry et al. SYNAPSE
- Update on Typical and Atypical Antipsychotic Drugs
- (2012) Herbert Y. Meltzer Annual Review of Medicine
- A new perspective for schizophrenia: TAAR1 agonists reveal antipsychotic- and antidepressant-like activity, improve cognition and control body weight
- (2012) F G Revel et al. MOLECULAR PSYCHIATRY
- Serotonergic transcriptional networks and potential importance to mental health
- (2012) Evan S Deneris et al. NATURE NEUROSCIENCE
- Serotonin in the Modulation of Neural Plasticity and Networks: Implications for Neurodevelopmental Disorders
- (2012) Klaus-Peter Lesch et al. NEURON
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- (2012) Florent G Revel et al. NEUROPSYCHOPHARMACOLOGY
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- (2011) B. Di Cara et al. JOURNAL OF NEUROSCIENCE
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- (2011) F. G. Revel et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
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- (2010) Prem N Yadav et al. NEUROPSYCHOPHARMACOLOGY
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- (2009) A. Bradaia et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- The role of 5-HT1A receptors in learning and memory
- (2008) Sven Ove Ögren et al. BEHAVIOURAL BRAIN RESEARCH
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- (2008) L. S. Barak et al. MOLECULAR PHARMACOLOGY
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