TAAR1 dependent and independent actions of the potential antipsychotic and dual TAAR1/5-HT1A receptor agonist SEP-383856
出版年份 2022 全文链接
标题
TAAR1 dependent and independent actions of the potential antipsychotic and dual TAAR1/5-HT1A receptor agonist SEP-383856
作者
关键词
-
出版物
NEUROPSYCHOPHARMACOLOGY
Volume 47, Issue 13, Pages 2319-2329
出版商
Springer Science and Business Media LLC
发表日期
2022-09-13
DOI
10.1038/s41386-022-01421-2
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Update on GPCR-based targets for the development of novel antidepressants
- (2021) Ioannis Mantas et al. MOLECULAR PSYCHIATRY
- Towards Novel Treatments for Schizophrenia: Molecular and Behavioural Signatures of the Psychotropic Agent SEP-363856
- (2021) Veronica Begni et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Trace Amine-Associated Receptor 1 Contributes to Diverse Functional Actions of O-Phenyl-Iodotyramine in Mice but Not to the Effects of Monoamine-Based Antidepressants
- (2021) Ioannis Mantas et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Binding of SEP-363856 within TAAR1 and the 5HT1A receptor: implications for the design of novel antipsychotic drugs
- (2021) Pramod C. Nair et al. MOLECULAR PSYCHIATRY
- Trace Amine-Associated Receptor 1 Trafficking to Cilia of Thyroid Epithelial Cells
- (2021) Maria Qatato et al. Cells
- Therapeutic Potential of TAAR1 Agonists in Schizophrenia: Evidence from Preclinical Models and Clinical Studies
- (2021) Nina Dedic et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- The G protein database, GproteinDb
- (2021) Gáspár Pándy-Szekeres et al. NUCLEIC ACIDS RESEARCH
- Ulotaront: A TAAR1 Agonist for the Treatment of Schizophrenia
- (2021) Michele L. R. Heffernan et al. ACS Medicinal Chemistry Letters
- Safety and effectiveness of ulotaront (SEP-363856) in schizophrenia: results of a 6-month, open-label extension study
- (2021) Christoph U. Correll et al. npj Schizophrenia
- A Non–D2-Receptor-Binding Drug for the Treatment of Schizophrenia
- (2020) Kenneth S. Koblan et al. NEW ENGLAND JOURNAL OF MEDICINE
- Low intrinsic efficacy for G protein activation can explain the improved side effect profiles of new opioid agonists
- (2020) Alexander Gillis et al. Science Signaling
- Trace Amine-Associated Receptor 1 (TAAR1): A new drug target for psychiatry?
- (2020) Seetal Dodd et al. NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS
- Location Bias as Emerging Paradigm in GPCR Biology and Drug Discovery
- (2020) Mohammad Ali Mohammad Nezhady et al. iScience
- TAAR1 dependent and independent actions of tyramine in interaction with glutamate underlie central effects of monoamine oxidase inhibition
- (2020) Ioannis Mantas et al. BIOLOGICAL PSYCHIATRY
- Illuminating G-Protein-Coupling Selectivity of GPCRs
- (2019) Asuka Inoue et al. CELL
- SEP-363856, A NOVEL PSYCHOTROPIC AGENT WITH A UNIQUE, NON-D2 RECEPTOR MECHANISM OF ACTION
- (2019) Nina Dedic et al. JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS
- Amphetamines signal through intracellular TAAR1 receptors coupled to Gα13 and GαS in discrete subcellular domains
- (2019) Suzanne M. Underhill et al. MOLECULAR PSYCHIATRY
- Mini G protein probes for active G protein–coupled receptors (GPCRs) in live cells
- (2018) Qingwen Wan et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Trace Amines and Their Receptors
- (2018) Raul R. Gainetdinov et al. PHARMACOLOGICAL REVIEWS
- Global Epidemiology and Burden of Schizophrenia: Findings From the Global Burden of Disease Study 2016
- (2018) Fiona J Charlson et al. SCHIZOPHRENIA BULLETIN
- Management of common adverse effects of antipsychotic medications
- (2018) T. Scott Stroup et al. World Psychiatry
- Increased context-dependent conditioning to amphetamine in mice lacking TAAR1
- (2016) Ilya Sukhanov et al. PHARMACOLOGICAL RESEARCH
- New functional activity of aripiprazole revealed: Robust antagonism of D2 dopamine receptor-stimulated Gβγ signaling
- (2015) Tarsis F. Brust et al. BIOCHEMICAL PHARMACOLOGY
- Learning from the past and looking to the future: Emerging perspectives for improving the treatment of psychiatric disorders
- (2015) Mark J. Millan et al. EUROPEAN NEUROPSYCHOPHARMACOLOGY
- Modulation by Trace Amine-Associated Receptor 1 of Experimental Parkinsonism, L-DOPA Responsivity, and Glutamatergic Neurotransmission
- (2015) A. Alvarsson et al. JOURNAL OF NEUROSCIENCE
- TAAR1 Modulates Cortical Glutamate NMDA Receptor Function
- (2015) Stefano Espinoza et al. NEUROPSYCHOPHARMACOLOGY
- Tissue-based map of the human proteome
- (2015) M. Uhlen et al. SCIENCE
- History of the Discovery of the Antipsychotic Dopamine D2 Receptor: A Basis for the Dopamine Hypothesis of Schizophrenia
- (2013) Bertha K. Madras Journal of the History of the Neurosciences
- Membrane permeability of trace amines: Evidence for a regulated, activity-dependent, nonexocytotic, synaptic release
- (2013) Mark D. Berry et al. SYNAPSE
- Update on Typical and Atypical Antipsychotic Drugs
- (2012) Herbert Y. Meltzer Annual Review of Medicine
- A new perspective for schizophrenia: TAAR1 agonists reveal antipsychotic- and antidepressant-like activity, improve cognition and control body weight
- (2012) F G Revel et al. MOLECULAR PSYCHIATRY
- Serotonergic transcriptional networks and potential importance to mental health
- (2012) Evan S Deneris et al. NATURE NEUROSCIENCE
- Serotonin in the Modulation of Neural Plasticity and Networks: Implications for Neurodevelopmental Disorders
- (2012) Klaus-Peter Lesch et al. NEURON
- Brain-Specific Overexpression of Trace Amine-Associated Receptor 1 Alters Monoaminergic Neurotransmission and Decreases Sensitivity to Amphetamine
- (2012) Florent G Revel et al. NEUROPSYCHOPHARMACOLOGY
- Genetic Deletion of Trace Amine 1 Receptors Reveals Their Role in Auto-Inhibiting the Actions of Ecstasy (MDMA)
- (2011) B. Di Cara et al. JOURNAL OF NEUROSCIENCE
- Agonist-specific voltage sensitivity at the dopamine D2S receptor – Molecular determinants and relevance to therapeutic ligands
- (2011) Kristoffer Sahlholm et al. NEUROPHARMACOLOGY
- TAAR1 activation modulates monoaminergic neurotransmission, preventing hyperdopaminergic and hypoglutamatergic activity
- (2011) F. G. Revel et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- The Presynaptic Component of the Serotonergic System is Required for Clozapine's Efficacy
- (2010) Prem N Yadav et al. NEUROPSYCHOPHARMACOLOGY
- The selective antagonist EPPTB reveals TAAR1-mediated regulatory mechanisms in dopaminergic neurons of the mesolimbic system
- (2009) A. Bradaia et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- The role of 5-HT1A receptors in learning and memory
- (2008) Sven Ove Ögren et al. BEHAVIOURAL BRAIN RESEARCH
- Pharmacological Characterization of Membrane-Expressed Human Trace Amine-Associated Receptor 1 (TAAR1) by a Bioluminescence Resonance Energy Transfer cAMP Biosensor
- (2008) L. S. Barak et al. MOLECULAR PHARMACOLOGY
Find the ideal target journal for your manuscript
Explore over 38,000 international journals covering a vast array of academic fields.
SearchAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started