Trace Amine-Associated Receptor 1 Contributes to Diverse Functional Actions of O-Phenyl-Iodotyramine in Mice but Not to the Effects of Monoamine-Based Antidepressants

Safety and Effectiveness of SEP−363856 in Schizophrenia: Results of a 6-Month, Open-Label Extension Study

(2021) Christoph U. Correll et al.   CNS SPECTRUMS

T1AM-TAAR1 signalling protects against OGD-induced synaptic dysfunction in the entorhinal cortex

(2021) Francesca Tozzi et al.   NEUROBIOLOGY OF DISEASE

Trace Amine-Associated Receptor 5 Provides Olfactory Input Into Limbic Brain Areas and Modulates Emotional Behaviors and Serotonin Transmission

(2020) Stefano Espinoza et al.   Frontiers in Molecular Neuroscience

MDMA and TAAR1‐mediated RhoA Activation in Serotonin Neurons

(2020) Suzanne Underhill et al.   FASEB JOURNAL

3-Iodothyronamine and Derivatives: New Allies Against Metabolic Syndrome?

(2020) Grazia Rutigliano et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

A Non–D2-Receptor-Binding Drug for the Treatment of Schizophrenia

(2020) Kenneth S. Koblan et al.   NEW ENGLAND JOURNAL OF MEDICINE

TAAR1 dependent and independent actions of tyramine in interaction with glutamate underlie central effects of monoamine oxidase inhibition

(2020) Ioannis Mantas et al.   BIOLOGICAL PSYCHIATRY

3-iodothyronamine – a thyroid hormone metabolite with distinct target profiles and mode of action

(2019) Josef Köhrle et al.   ENDOCRINE REVIEWS

SEP-363856, A NOVEL PSYCHOTROPIC AGENT WITH A UNIQUE, NON-D2 RECEPTOR MECHANISM OF ACTION

(2019) Nina Dedic et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

Amphetamines signal through intracellular TAAR1 receptors coupled to Gα13 and GαS in discrete subcellular domains

(2019) Suzanne M. Underhill et al.   MOLECULAR PSYCHIATRY

Molecular Variants in Human Trace Amine-Associated Receptors and Their Implications in Mental and Metabolic Disorders

(2019) Grazia Rutigliano et al.   CELLULAR AND MOLECULAR NEUROBIOLOGY

Trace amine associated receptor 1 (TAAR1) modulators: a patent review (2010-present)

(2019) Michele Tonelli et al.   EXPERT OPINION ON THERAPEUTIC PATENTS

Exogenous 3-Iodothyronamine Rescues the Entorhinal Cortex from β-Amyloid Toxicity

(2019) Alice Accorroni et al.   THYROID

Trace Amines and Their Receptors

(2018) Raul R. Gainetdinov et al.   PHARMACOLOGICAL REVIEWS

The Case for TAAR1 as a Modulator of Central Nervous System Function

(2018) Grazia Rutigliano et al.   Frontiers in Pharmacology

Striatal Tyrosine Hydroxylase Is Stimulated via TAAR1 by 3-Iodothyronamine, But Not by Tyramine or β-Phenylethylamine

(2018) Xiaoqun Zhang et al.   Frontiers in Pharmacology

Central Effects of 3-Iodothyronamine Reveal a Novel Role for Mitochondrial Monoamine Oxidases

(2018) Annunziatina Laurino et al.   Frontiers in Endocrinology

3-Iodothyronamine Induces Tail Vasodilation Through Central Action in Male Mice

(2017) Sogol Gachkar et al.   ENDOCRINOLOGY

Dopamine System Dysregulation in Major Depressive Disorders

(2017) Pauline Belujon et al.   INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY

Thyronamines and Analogues - The Route from Rediscovery to Translational Research on Thyronergic Amines

(2017) Grazia Chiellini et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Pharmacology of human trace amine-associated receptors: Therapeutic opportunities and challenges

(2017) Mark D. Berry et al.   PHARMACOLOGY & THERAPEUTICS

Warm-Sensitive Neurons that Control Body Temperature

(2016) Chan Lek Tan et al.   CELL

Trace amine-associated receptors: ligands, neural circuits, and behaviors

(2015) Stephen D Liberles   CURRENT OPINION IN NEUROBIOLOGY

Effects of acute microinjections of the thyroid hormone derivative 3-iodothyronamine to the preoptic region of adult male rats on sleep, thermoregulation and motor activity

(2013) Thomas D. James et al.   HORMONES AND BEHAVIOR

Biosynthesis of 3-Iodothyronamine (T1AM) Is Dependent on the Sodium-Iodide Symporter and Thyroperoxidase but Does Not Involve Extrathyroidal Metabolism of T4

(2012) Sarah A. Hackenmueller et al.   ENDOCRINOLOGY

A new perspective for schizophrenia: TAAR1 agonists reveal antipsychotic- and antidepressant-like activity, improve cognition and control body weight

(2012) F G Revel et al.   MOLECULAR PSYCHIATRY

Thyronamines—Past, Present, and Future

(2011) S. Piehl et al.   ENDOCRINE REVIEWS

Genetic Deletion of Trace Amine 1 Receptors Reveals Their Role in Auto-Inhibiting the Actions of Ecstasy (MDMA)

(2011) B. Di Cara et al.   JOURNAL OF NEUROSCIENCE

Does the aromatic l-amino acid decarboxylase contribute to thyronamine biosynthesis?

(2011) Carolin S. Hoefig et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

TAAR1 activation modulates monoaminergic neurotransmission, preventing hyperdopaminergic and hypoglutamatergic activity

(2011) F. G. Revel et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Normal thermoregulatory responses to 3-iodothyronamine, trace amines and amphetamine-like psychostimulants in trace amine associated receptor 1 knockout mice

(2010) Helen N. Panas et al.   JOURNAL OF NEUROSCIENCE RESEARCH

International Union of Pharmacology. LXXII. Recommendations for Trace Amine Receptor Nomenclature

(2009) J. J. Maguire et al.   PHARMACOLOGICAL REVIEWS

The selective antagonist EPPTB reveals TAAR1-mediated regulatory mechanisms in dopaminergic neurons of the mesolimbic system

(2009) A. Bradaia et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The molecular neurobiology of depression

(2008) Vaishnav Krishnan et al.   NATURE

CRF1 Not Glucocorticoid Receptors Mediate Prepulse Inhibition Deficits in Mice Overexpressing CRF

(2007) Lucianne Groenink et al.   BIOLOGICAL PSYCHIATRY

Trace amine-associated receptors and their ligands

(2006) R Zucchi et al.   BRITISH JOURNAL OF PHARMACOLOGY