Nucleus-translocated mitochondrial cytochrome c liberates nucleophosmin-sequestered ARF tumor suppressor by changing nucleolar liquid–liquid phase separation

Mitochondrial cytochrome c shot towards histone chaperone condensates in the nucleus

(2021) Katiuska González‐Arzola et al.   FEBS Open Bio

Inhibition of the PP2A activity by the histone chaperone ANP32B is long-range allosterically regulated by respiratory cytochrome c

(2021) Francisco Rivero-Rodríguez et al.   Redox Biology

Proposed mechanism for regulation of H 2 O 2 ‐induced programmed cell death in plants by binding of cytochrome c to 14‐3‐3 proteins

(2020) Carlos A. Elena‐Real et al.   PLANT JOURNAL

Lysine/RNA-interactions drive and regulate biomolecular condensation

(2019) Tina Ukmar-Godec et al.   Nature Communications

Macromolecular structure determination using X-rays, neutrons and electrons: recent developments in Phenix

(2019) Dorothee Liebschner et al.   Acta Crystallographica Section D-Structural Biology

New moonlighting functions of mitochondrial cytochrome c in the cytoplasm and nucleus

(2019) Katiuska González‐Arzola et al.   FEBS LETTERS

NPM1 exhibits structural and dynamic heterogeneity upon phase separation with the p14ARF tumor suppressor

(2019) Eric Gibbs et al.   JOURNAL OF MAGNETIC RESONANCE

Identification of a novel nucleophosmin-interaction motif in the tumor suppressor p14arf

(2018) Enrico Luchinat et al.   FEBS Journal

Cytochrome c speeds up caspase cascade activation by blocking 14-3-3ε-dependent Apaf-1 inhibition

(2018) Carlos A. Elena-Real et al.   Cell Death & Disease

Self-interaction of NPM1 modulates multiple mechanisms of liquid–liquid phase separation

(2018) Diana M. Mitrea et al.   Nature Communications

Fluorescence-based quantification of nucleocytoplasmic transport

(2018) Joshua B. Kelley et al.   METHODS

In Cellulo Protein-mRNA Interaction Assay to Determine the Action of G-Quadruplex-Binding Molecules

(2018) Rodrigo Prado Martins et al.   MOLECULES

Structural basis of mitochondrial dysfunction in response to cytochromecphosphorylation at tyrosine 48

(2017) Blas Moreno-Beltrán et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Nucleophosmin: from structure and function to disease development

(2016) Joseph K. Box et al.   BMC MOLECULAR BIOLOGY

Scipion: A software framework toward integration, reproducibility and validation in 3D electron microscopy

(2016) J.M. de la Rosa-Trevín et al.   JOURNAL OF STRUCTURAL BIOLOGY

Histone chaperone activity of Arabidopsis thaliana NRP1 is blocked by cytochrome c

(2016) Katiuska González-Arzola et al.   NUCLEIC ACIDS RESEARCH

Stage-Specific Changes in the Water, Na+, Cl- and K+ Contents of Organelles during Apoptosis, Demonstrated by a Targeted Cryo Correlative Analytical Approach

(2016) Frédérique Nolin et al.   PLoS One

Molecules that target nucleophosmin for cancer treatment: an update

(2016) Adele Di Matteo et al.   Oncotarget

Nucleophosmin integrates within the nucleolus via multi-modal interactions with proteins displaying R-rich linear motifs and rRNA

(2016) Diana M Mitrea et al.   eLife

Structural basis for inhibition of the histone chaperone activity of SET/TAF-Iβ by cytochromec

(2015) Katiuska González-Arzola et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Cytochrome c1 exhibits two binding sites for cytochrome c in plants

(2014) Blas Moreno-Beltrán et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

Structural and Functional Analysis of Novel Human CytochromecTargets in Apoptosis

(2014) Jonathan Martínez-Fábregas et al.   MOLECULAR & CELLULAR PROTEOMICS

Structural polymorphism in the N-terminal oligomerization domain of NPM1

(2014) D. M. Mitrea et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A common signalosome for programmed cell death in humans and plants

(2014) J Martínez-Fábregas et al.   Cell Death & Disease

NewArabidopsis thalianaCytochromecPartners: A Look Into the Elusive Role of Cytochromecin Programmed Cell Death in Plants

(2013) Jonathan Martínez-Fábregas et al.   MOLECULAR & CELLULAR PROTEOMICS

High-resolution noise substitution to measure overfitting and validate resolution in 3D structure determination by single particle electron cryomicroscopy

(2013) Shaoxia Chen et al.   ULTRAMICROSCOPY

Knockdown of NPM1 by RNA Interference Inhibits Cells Proliferation and Induces Apoptosis in Leukemic Cell Line

(2012) Feng-Xian Qin et al.   International Journal of Medical Sciences

Cytochrome c signalosome in mitochondria

(2011) Irene Díaz-Moreno et al.   EUROPEAN BIOPHYSICS JOURNAL WITH BIOPHYSICS LETTERS

L-Ilf3 and L-NF90 Traffic to the Nucleolus Granular Component: Alternatively-Spliced Exon 3 Encodes a Nucleolar Localization Motif

(2011) Wildriss Viranaicken et al.   PLoS One

XDS

(2010) Wolfgang Kabsch   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

B23 acts as a nucleolar stress sensor and promotes cell survival through its dynamic interaction with hnRNPU and hnRNPA1

(2010) Z Yao et al.   ONCOGENE

Molecular replacement withMOLREP

(2009) Alexei Vagin et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Structural Consequences of Nucleophosmin Mutations in Acute Myeloid Leukemia

(2008) Charles G. Grummitt et al.   JOURNAL OF BIOLOGICAL CHEMISTRY