Shared and distinct biological circuits in effector, memory and exhausted CD8+ T cells revealed by temporal single-cell transcriptomics and epigenetics
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Title
Shared and distinct biological circuits in effector, memory and exhausted CD8+ T cells revealed by temporal single-cell transcriptomics and epigenetics
Authors
Keywords
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Journal
NATURE IMMUNOLOGY
Volume -, Issue -, Pages -
Publisher
Springer Science and Business Media LLC
Online
2022-10-22
DOI
10.1038/s41590-022-01338-4
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Note: Only part of the references are listed.- Human epigenetic and transcriptional T cell differentiation atlas for identifying functional T cell-specific enhancers
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- (2019) Alexander C. Huang et al. NATURE MEDICINE
- The cis-Regulatory Atlas of the Mouse Immune System
- (2019) Hideyuki Yoshida et al. CELL
- Tissue-Resident T Cells and Other Resident Leukocytes
- (2019) David Masopust et al. Annual Review of Immunology
- CD8 T Cell Exhaustion During Chronic Viral Infection and Cancer
- (2019) Laura M. McLane et al. Annual Review of Immunology
- TOX reinforces the phenotype and longevity of exhausted T cells in chronic viral infection
- (2019) Francesca Alfei et al. NATURE
- TOX is a critical regulator of tumour-specific T cell differentiation
- (2019) Andrew C. Scott et al. NATURE
- TOX transcriptionally and epigenetically programs CD8+ T cell exhaustion
- (2019) Omar Khan et al. NATURE
- Single-cell RNA-seq reveals TOX as a key regulator of CD8+ T cell persistence in chronic infection
- (2019) Chen Yao et al. NATURE IMMUNOLOGY
- TCF-1-Centered Transcriptional Network Drives an Effector versus Exhausted CD8 T Cell-Fate Decision
- (2019) Zeyu Chen et al. IMMUNITY
- Proliferating Transitory T Cells with an Effector-like Transcriptional Signature Emerge from PD-1+ Stem-like CD8+ T Cells during Chronic Infection
- (2019) William H. Hudson et al. IMMUNITY
- CD4+ T Cell Help Is Required for the Formation of a Cytolytic CD8+ T Cell Subset that Protects against Chronic Infection and Cancer
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- ZEB1, ZEB2, and the miR-200 family form a counterregulatory network to regulate CD8+T cell fates
- (2018) Tianxia Guan et al. JOURNAL OF EXPERIMENTAL MEDICINE
- NKG2A Blockade Potentiates CD8 T Cell Immunity Induced by Cancer Vaccines
- (2018) Nadine van Montfoort et al. CELL
- Tumor suppressors BTG1 and BTG2: Beyond growth control
- (2018) Laurensia Yuniati et al. JOURNAL OF CELLULAR PHYSIOLOGY
- Defining Memory CD8 T Cell
- (2018) Matthew D. Martin et al. Frontiers in Immunology
- Dysregulated cellular functions and cell stress pathways provide critical cues for activating and targeting natural killer cells to transformed and infected cells
- (2017) David H. Raulet et al. IMMUNOLOGICAL REVIEWS
- Runx3 programs CD8+ T cell residency in non-lymphoid tissues and tumours
- (2017) J. Justin Milner et al. NATURE
- Chromatin states define tumour-specific T cell dysfunction and reprogramming
- (2017) Mary Philip et al. NATURE
- Optimized retroviral transduction of mouse T cells for in vivo assessment of gene function
- (2017) Makoto Kurachi et al. Nature Protocols
- T Cell Factor 1-Expressing Memory-like CD8 + T Cells Sustain the Immune Response to Chronic Viral Infections
- (2016) Daniel T. Utzschneider et al. IMMUNITY
- Defining CD8+ T cells that provide the proliferative burst after PD-1 therapy
- (2016) Se Jin Im et al. NATURE
- Lineage-specific and single-cell chromatin accessibility charts human hematopoiesis and leukemia evolution
- (2016) M Ryan Corces et al. NATURE GENETICS
- The epigenetic landscape of T cell exhaustion
- (2016) D. R. Sen et al. SCIENCE
- Epigenetic stability of exhausted T cells limits durability of reinvigoration by PD-1 blockade
- (2016) K. E. Pauken et al. SCIENCE
- The transcription factors ZEB2 and T-bet cooperate to program cytotoxic T cell terminal differentiation in response to LCMV viral infection
- (2015) Claudia X. Dominguez et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Transcriptional repressor ZEB2 promotes terminal differentiation of CD8 + effector and memory T cell populations during infection
- (2015) Kyla D. Omilusik et al. JOURNAL OF EXPERIMENTAL MEDICINE
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- (2012) J. M. Angelosanto et al. JOURNAL OF VIROLOGY
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- Selective expansion of a subset of exhausted CD8 T cells by PD-L1 blockade
- (2008) S. D. Blackburn et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
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