ZEB1, ZEB2, and the miR-200 family form a counterregulatory network to regulate CD8+T cell fates

Polycomb Repressive Complex 2-Mediated Chromatin Repression Guides Effector CD8 + T Cell Terminal Differentiation and Loss of Multipotency

(2017) Simon M. Gray et al.   IMMUNITY

Transcriptional Regulation of Tissue-Resident Lymphocytes

(2017) Laura K. Mackay et al.   TRENDS IN IMMUNOLOGY

The Chemokine Receptor CX3CR1 Defines Three Antigen-Experienced CD8 T Cell Subsets with Distinct Roles in Immune Surveillance and Homeostasis

(2016) Carmen Gerlach et al.   IMMUNITY

A molecular threshold for effector CD8+ T cell differentiation controlled by transcription factors Blimp-1 and T-bet

(2016) Annie Xin et al.   NATURE IMMUNOLOGY

BACH2 regulates CD8+ T cell differentiation by controlling access of AP-1 factors to enhancers

(2016) Rahul Roychoudhuri et al.   NATURE IMMUNOLOGY

Hobit and Blimp1 instruct a universal transcriptional program of tissue residency in lymphocytes

(2016) L. K. Mackay et al.   SCIENCE

The transcription factors ZEB2 and T-bet cooperate to program cytotoxic T cell terminal differentiation in response to LCMV viral infection

(2015) Claudia X. Dominguez et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Transcriptional repressor ZEB2 promotes terminal differentiation of CD8 + effector and memory T cell populations during infection

(2015) Kyla D. Omilusik et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Terminal NK cell maturation is controlled by concerted actions of T-bet and Zeb2 and is essential for melanoma rejection

(2015) Mary J. van Helden et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Characterization of the mammalian miRNA turnover landscape

(2015) Yanwen Guo et al.   NUCLEIC ACIDS RESEARCH

Transforming growth factor-β signaling is constantly shaping memory T-cell population

(2015) Chaoyu Ma et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Alternative Capture of Noncoding RNAs or Protein-Coding Genes by Herpesviruses to Alter Host T Cell Function

(2014) Yang Eric Guo et al.   MOLECULAR CELL

The Pitx2:miR-200c/141:noggin pathway regulates Bmp signaling and ameloblast differentiation

(2013) H. Cao et al.   DEVELOPMENT

The Transcription Factor Foxo1 Controls Central-Memory CD8+ T Cell Responses to Infection

(2013) Myoungjoo V. Kim et al.   IMMUNITY

Effector-like CD8+ T Cells in the Memory Population Mediate Potent Protective Immunity

(2013) Janelle A. Olson et al.   IMMUNITY

Id2 Influences Differentiation of Killer Cell Lectin-like Receptor G1hi Short-Lived CD8+ Effector T Cells

(2013) J. Knell et al.   JOURNAL OF IMMUNOLOGY

FoxO1 Controls Effector-to-Memory Transition and Maintenance of Functional CD8 T Cell Memory

(2013) M. M. Tejera et al.   JOURNAL OF IMMUNOLOGY

The developmental pathway for CD103+CD8+ tissue-resident memory T cells of skin

(2013) Laura K Mackay et al.   NATURE IMMUNOLOGY

Critical regulation of miR-200/ZEB2 pathway in Oct4/Sox2-induced mesenchymal-to-epithelial transition and induced pluripotent stem cell generation

(2013) G. Wang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

MiR-200b and miR-429 Function in Mouse Ovulation and Are Essential for Female Fertility

(2013) H. Hasuwa et al.   SCIENCE

Antigen-Independent Differentiation and Maintenance of Effector-like Resident Memory T Cells in Tissues

(2012) K. A. Casey et al.   JOURNAL OF IMMUNOLOGY

The ZEB1/miR-200 feedback loop controls Notch signalling in cancer cells

(2011) Simone Brabletz et al.   EMBO JOURNAL

Environmental and Antigen Receptor-Derived Signals Support Sustained Surveillance of the Lungs by Pathogen-Specific Cytotoxic T Lymphocytes

(2011) Y.-T. Lee et al.   JOURNAL OF VIROLOGY

An autocrine TGF-β/ZEB/miR-200 signaling network regulates establishment and maintenance of epithelial-mesenchymal transition

(2011) Philip A. Gregory et al.   MOLECULAR BIOLOGY OF THE CELL

Integrative Regulatory Mapping Indicates that the RNA-Binding Protein HuR Couples Pre-mRNA Processing and mRNA Stability

(2011) Neelanjan Mukherjee et al.   MOLECULAR CELL

Repression of the DNA-binding inhibitor Id3 by Blimp-1 limits the formation of memory CD8+ T cells

(2011) Yun Ji et al.   NATURE IMMUNOLOGY

The transcriptional regulators Id2 and Id3 control the formation of distinct memory CD8+ T cell subsets

(2011) Cliff Y Yang et al.   NATURE IMMUNOLOGY

Immunological mechanisms of vaccination

(2011) Bali Pulendran et al.   NATURE IMMUNOLOGY

The role of the miR-200 family in epithelial-mesenchymal transition

(2010) Perry S. Mongroo et al.   CANCER BIOLOGY & THERAPY

The ZEB/miR-200 feedback loop—a motor of cellular plasticity in development and cancer?

(2010) Simone Brabletz et al.   EMBO REPORTS

Prolonged Interleukin-2Rα Expression on Virus-Specific CD8+ T Cells Favors Terminal-Effector Differentiation In Vivo

(2010) Vandana Kalia et al.   IMMUNITY

Interleukin-2 and Inflammation Induce Distinct Transcriptional Programs that Promote the Differentiation of Effector Cytolytic T Cells

(2010) Matthew E. Pipkin et al.   IMMUNITY

Differentiation and Persistence of Memory CD8+ T Cells Depend on T Cell Factor 1

(2010) Xinyuan Zhou et al.   IMMUNITY

Cutting Edge: The Transcription Factor Eomesodermin Enables CD8+ T Cells To Compete for the Memory Cell Niche

(2010) A. Banerjee et al.   JOURNAL OF IMMUNOLOGY

Essential role of the Wnt pathway effector Tcf-1 for the establishment of functional CD8 T cell memory

(2010) G. Jeannet et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Transcriptional Repressor Blimp-1 Promotes CD8+ T Cell Terminal Differentiation and Represses the Acquisition of Central Memory T Cell Properties

(2009) Rachel L. Rutishauser et al.   IMMUNITY

Diversity in T Cell Memory: An Embarrassment of Riches

(2009) Stephen C. Jameson et al.   IMMUNITY

Analysis of Interleukin-21-Induced Prdm1 Gene Regulation Reveals Functional Cooperation of STAT3 and IRF4 Transcription Factors

(2009) Hyokjoon Kwon et al.   IMMUNITY

Blimp-1 Transcription Factor Is Required for the Differentiation of Effector CD8+ T Cells and Memory Responses

(2009) Axel Kallies et al.   IMMUNITY

The transcription repressor, ZEB1, cooperates with CtBP2 and HDAC1 to suppress IL-2 gene activation in T cells

(2009) J. Wang et al.   INTERNATIONAL IMMUNOLOGY

Runx3 and T-box proteins cooperate to establish the transcriptional program of effector CTLs

(2009) Fernando Cruz-Guilloty et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Enhancing CD8 T-cell memory by modulating fatty acid metabolism

(2009) Erika L. Pearce et al.   NATURE

A Double-Negative Feedback Loop between ZEB1-SIP1 and the microRNA-200 Family Regulates Epithelial-Mesenchymal Transition

(2008) C. P. Bracken et al.   CANCER RESEARCH

The Immunological Genome Project: networks of gene expression in immune cells

(2008) Tracy S P Heng et al.   NATURE IMMUNOLOGY

Anomalous Type 17 Response to Viral Infection by CD8+ T Cells Lacking T-bet and Eomesodermin

(2008) A. M. Intlekofer et al.   SCIENCE