Developmental Relationships of Four Exhausted CD8+ T Cell Subsets Reveals Underlying Transcriptional and Epigenetic Landscape Control Mechanisms

Title
Developmental Relationships of Four Exhausted CD8+ T Cell Subsets Reveals Underlying Transcriptional and Epigenetic Landscape Control Mechanisms
Authors
Keywords
exhaustion, CD8, TCF1, Tox, T-bet, epigenetics, PD-1 blockade, T cell exhaustion lineage, chronic infection, cancer immunotherapy
Journal
IMMUNITY
Volume 52, Issue 5, Pages 825-841.e8
Publisher
Elsevier BV
Online
2020-05-11
DOI
10.1016/j.immuni.2020.04.014

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