A wheat resistosome defines common principles of immune receptor channels

The stem rust effector protein AvrSr50 escapes Sr50 recognition by a substitution in a single surface‐exposed residue

(2022) Diana Ortiz et al.   NEW PHYTOLOGIST

Resistosomes at the interface of pathogens and plants

(2022) Alexander Förderer et al.   CURRENT OPINION IN PLANT BIOLOGY

New recognition specificity in a plant immune receptor by molecular engineering of its integrated domain

(2022) Stella Cesari et al.   Nature Communications

A five-transgene cassette confers broad-spectrum resistance to a fungal rust pathogen in wheat

(2021) Ming Luo et al.   NATURE BIOTECHNOLOGY

The ZAR1 resistosome is a calcium-permeable channel triggering plant immune signaling

(2021) Guozhi Bi et al.   CELL

Highly accurate protein structure prediction with AlphaFold

(2021) John Jumper et al.   NATURE

Plant “helper” immune receptors are Ca2+-permeable nonselective cation channels

(2021) Pierre Jacob et al.   SCIENCE

A recombined Sr26 and Sr61 disease resistance gene stack in wheat encodes unrelated NLR genes

(2021) Jianping Zhang et al.   Nature Communications

Population genomic analysis of Aegilops tauschii identifies targets for bread wheat improvement

(2021) Kumar Gaurav et al.   NATURE BIOTECHNOLOGY

A designer rice NLR immune receptor confers resistance to the rice blast fungus carrying noncorresponding avirulence effectors

(2021) Yang Liu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Resistosome and inflammasome: platforms mediating innate immunity

(2020) Yehui Xiong et al.   CURRENT OPINION IN PLANT BIOLOGY

CRISPR/Cas9 Gene Editing of Gluten in Wheat to Reduce Gluten Content and Exposure—Reviewing Methods to Screen for Coeliac Safety

(2020) Aurelie Jouanin et al.   Frontiers in Nutrition

Direct pathogen-induced assembly of an NLR immune receptor complex to form a holoenzyme

(2020) Shoucai Ma et al.   SCIENCE

Structure of the activated ROQ1 resistosome directly recognizing the pathogen effector XopQ

(2020) Raoul Martin et al.   SCIENCE

Resistance gene cloning from a wild crop relative by sequence capture and association genetics

(2019) Sanu Arora et al.   NATURE BIOTECHNOLOGY

Reconstitution and structure of a plant NLR resistosome conferring immunity

(2019) Jizong Wang et al.   SCIENCE

Ligand-triggered allosteric ADP release primes a plant NLR complex

(2019) Jizong Wang et al.   SCIENCE

The Plant “Resistosome”: Structural Insights into Immune Signaling

(2019) Hayden Burdett et al.   Cell Host & Microbe

Dissection of cell death induction by wheat stem rust resistance protein Sr35 and its matching effector AvrSr35

(2019) Stephen Bolus et al.   MOLECULAR PLANT-MICROBE INTERACTIONS

Protein engineering expands the effector recognition profile of a rice NLR immune receptor

(2019) Juan Carlos De la Concepcion et al.   eLife

A cell death assay in barley and wheat protoplasts for identification and validation of matching pathogen AVR effector and plant NLR immune receptors

(2019) Isabel M. L. Saur et al.   Plant Methods

An N-terminal motif in NLR immune receptors is functionally conserved across distantly related plant species

(2019) Hiroaki Adachi et al.   eLife

Identification and characterization of wheat stem rust resistance gene Sr21 effective against the Ug99 race group at high temperature

(2018) Shisheng Chen et al.   PLoS Genetics

Genome-wide functional analyses of plant coiled–coil NLR-type pathogen receptors reveal essential roles of their N-terminal domain in oligomerization, networking, and immunity

(2018) Tadeusz Wróblewski et al.   PLOS BIOLOGY

Deadly new wheat disease threatens Europe’s crops

(2017) Shaoni Bhattacharya   NATURE

MotionCor2: anisotropic correction of beam-induced motion for improved cryo-electron microscopy

(2017) Shawn Q Zheng et al.   NATURE METHODS

Multiple strategies for pathogen perception by plant immune receptors

(2017) Stella Cesari   NEW PHYTOLOGIST

Low-gluten, nontransgenic wheat engineered with CRISPR/Cas9

(2017) Susana Sánchez-León et al.   PLANT BIOTECHNOLOGY JOURNAL

The NBS-LRR architectures of plant R-proteins and metazoan NLRs evolved in independent events

(2017) Jonathan M. Urbach et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Identification and characterization ofSr13, a tetraploid wheat gene that confers resistance to the Ug99 stem rust race group

(2017) Wenjun Zhang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Variation in theAvrSr35gene determinesSr35resistance against wheat stem rust race Ug99

(2017) Andres Salcedo et al.   SCIENCE

Rapid cloning of disease-resistance genes in plants using mutagenesis and sequence capture

(2016) Burkhard Steuernagel et al.   NATURE BIOTECHNOLOGY

Morphogenic Regulators Baby boom and Wuschel Improve Monocot Transformation

(2016) Keith Lowe et al.   PLANT CELL

Allelic barley MLA immune receptors recognize sequence-unrelated avirulence effectors of the powdery mildew pathogen

(2016) Xunli Lu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Atomic structure of the apoptosome: mechanism of cytochromec- and dATP-mediated activation of Apaf-1

(2015) Mengying Zhou et al.   GENES & DEVELOPMENT

Sampling the conformational space of the catalytic subunit of human γ-secretase

(2015) Xiao-chen Bai et al.   eLife

The wheat Sr50 gene reveals rich diversity at a cereal disease resistance locus

(2015) Rohit Mago et al.   Nature Plants

Efficient Agrobacterium transformation of elite wheat germplasm without selection

(2014) Terese Richardson et al.   PLANT CELL TISSUE AND ORGAN CULTURE

Apoptosome and inflammasome: conserved machineries for caspase activation

(2014) Jijie Chai et al.   National Science Review

Quantifying the local resolution of cryo-EM density maps

(2013) Alp Kucukelbir et al.   NATURE METHODS

Identification of Wheat Gene Sr35 That Confers Resistance to Ug99 Stem Rust Race Group

(2013) C. Saintenac et al.   SCIENCE

The Gene Sr33, an Ortholog of Barley Mla Genes, Encodes Resistance to Wheat Stem Rust Race Ug99

(2013) S. Periyannan et al.   SCIENCE

RELION: Implementation of a Bayesian approach to cryo-EM structure determination

(2012) Sjors H.W. Scheres   JOURNAL OF STRUCTURAL BIOLOGY

The Emergence of Ug99 Races of the Stem Rust Fungus is a Threat to World Wheat Production

(2011) Ravi P. Singh et al.   Annual Review of Phytopathology

A Bayesian View on Cryo-EM Structure Determination

(2011) Sjors H.W. Scheres   JOURNAL OF MOLECULAR BIOLOGY

Features and development ofCoot

(2010) P. Emsley et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

PHENIX: a comprehensive Python-based system for macromolecular structure solution

(2010) Paul D. Adams et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

New baculovirus expression tools for recombinant protein complex production

(2010) Simon Trowitzsch et al.   JOURNAL OF STRUCTURAL BIOLOGY

Plant immunity: towards an integrated view of plant–pathogen interactions

(2010) Peter N. Dodds et al.   NATURE REVIEWS GENETICS

The Coiled-Coil and Nucleotide Binding Domains of the Potato Rx Disease Resistance Protein Function in Pathogen Recognition and Signaling

(2008) G. J. Rairdan et al.   PLANT CELL