Long-primed germinal centres with enduring affinity maturation and clonal migration

Germinal center responses to SARS-CoV-2 mRNA vaccines in healthy and immunocompromised individuals

(2022) Katlyn Lederer et al.   CELL

Germinal centre-driven maturation of B cell response to mRNA vaccination

(2022) Wooseob Kim et al.   NATURE

Rhesus and cynomolgus macaque immunoglobulin heavy-chain genotyping yields comprehensive databases of germline VDJ alleles

(2021) Néstor Vázquez Bernat et al.   IMMUNITY

Integrated analysis of multimodal single-cell data

(2021) Yuhan Hao et al.   CELL

SARS-CoV-2 mRNA vaccines induce persistent human germinal centre responses

(2021) Jackson S. Turner et al.   NATURE

Vaccine genetics of IGHV1-2 VRC01-class broadly neutralizing antibody precursor naïve human B cells

(2021) Jeong Hyun Lee et al.   npj Vaccines

Temporal dynamics of persistent germinal centers and memory B cell differentiation following respiratory virus infection

(2021) William T. Yewdell et al.   Cell Reports

Human B cell lineages associated with germinal centers following influenza vaccination are measurably evolving

(2021) Kenneth B Hoehn et al.   eLife

A particulate saponin/TLR agonist vaccine adjuvant alters lymph flow and modulates adaptive immunity

(2021) Murillo Silva et al.   Science Immunology

SARS-CoV-2 infection generates tissue-localized immunological memory in humans

(2021) Maya M.L. Poon et al.   Science Immunology

Novel specialized cell state and spatial compartments within the germinal center

(2020) Domenick E. Kennedy et al.   NATURE IMMUNOLOGY

Mapping Polyclonal Antibody Responses in Non-human Primates Vaccinated with HIV Env Trimer Subunit Vaccines

(2020) Bartek Nogal et al.   Cell Reports

Single-cell analysis of germinal-center B cells informs on lymphoma cell of origin and outcome

(2020) Antony B. Holmes et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Mapping Neutralizing Antibody Epitope Specificities to an HIV Env Trimer in Immunized and in Infected Rhesus Macaques

(2020) Fangzhu Zhao et al.   Cell Reports

Mapping the immunogenic landscape of near-native HIV-1 envelope trimers in non-human primates

(2020) Christopher A. Cottrell et al.   PLoS Pathogens

B Cell Responses: Cell Interaction Dynamics and Decisions

(2019) Jason G. Cyster et al.   CELL

Slow Delivery Immunization Enhances HIV Neutralizing Antibody and Germinal Center Responses via Modulation of Immunodominance

(2019) Kimberly M. Cirelli et al.   CELL

T Follicular Helper Cell Biology: A Decade of Discovery and Diseases

(2019) Shane Crotty   IMMUNITY

Multiple roles for HIV broadly neutralizing antibodies

(2019) Barton F. Haynes et al.   Science Translational Medicine

Correlates of adjuvanticity: A review on adjuvants in licensed vaccines

(2018) Giuseppe Del Giudice et al.   SEMINARS IN IMMUNOLOGY

Electron-Microscopy-Based Epitope Mapping Defines Specificities of Polyclonal Antibodies Elicited during HIV-1 BG505 Envelope Trimer Immunization

(2018) Matteo Bianchi et al.   IMMUNITY

New tools for automated high-resolution cryo-EM structure determination in RELION-3

(2018) Jasenko Zivanov et al.   eLife

Elicitation of Robust Tier 2 Neutralizing Antibody Responses in Nonhuman Primates by HIV Envelope Trimer Immunization Using Optimized Approaches

(2017) Matthias Pauthner et al.   IMMUNITY

Tfh cells and HIV bnAbs, an immunodominance model of the HIV neutralizing antibody generation problem

(2017) Colin Havenar-Daughton et al.   IMMUNOLOGICAL REVIEWS

Broadly Neutralizing Antibodies to HIV and Their Role in Vaccine Design

(2016) Dennis R. Burton et al.   Annual Review of Immunology

Germinal Center B Cell Dynamics

(2016) Luka Mesin et al.   IMMUNITY

HIV Vaccine Design to Target Germline Precursors of Glycan-Dependent Broadly Neutralizing Antibodies

(2016) Jon M. Steichen et al.   IMMUNITY

Cytokine-Independent Detection of Antigen-Specific Germinal Center T Follicular Helper Cells in Immunized Nonhuman Primates Using a Live Cell Activation-Induced Marker Technique

(2016) Colin Havenar-Daughton et al.   JOURNAL OF IMMUNOLOGY

Sustained antigen availability during germinal center initiation enhances antibody responses to vaccination

(2016) Hok Hei Tam et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

iNEXT: an R package for rarefaction and extrapolation of species diversity (Hill numbers)

(2016) T. C. Hsieh et al.   Methods in Ecology and Evolution

Direct Probing of Germinal Center Responses Reveals Immunological Features and Bottlenecks for Neutralizing Antibody Responses to HIV Env Trimer

(2016) Colin Havenar-Daughton et al.   Cell Reports

Murine Antibody Responses to Cleaved Soluble HIV-1 Envelope Trimers Are Highly Restricted in Specificity

(2015) Joyce K. Hu et al.   JOURNAL OF VIROLOGY

T cell help controls the speed of the cell cycle in germinal center B cells

(2015) A. D. Gitlin et al.   SCIENCE

pRESTO: a toolkit for processing high-throughput sequencing raw reads of lymphocyte receptor repertoires

(2014) Jason A. Vander Heiden et al.   BIOINFORMATICS

Clonal selection in the germinal centre by regulated proliferation and hypermutation

(2014) Alexander D. Gitlin et al.   NATURE

Endocytosis and Recycling of Immune Complexes by Follicular Dendritic Cells Enhances B Cell Antigen Binding and Activation

(2013) Balthasar A. Heesters et al.   IMMUNITY

Optimization and validation of the TZM-bl assay for standardized assessments of neutralizing antibodies against HIV-1

(2013) Marcella Sarzotti-Kelsoe et al.   JOURNAL OF IMMUNOLOGICAL METHODS

Global Panel of HIV-1 Env Reference Strains for Standardized Assessments of Vaccine-Elicited Neutralizing Antibodies

(2013) A. deCamp et al.   JOURNAL OF VIROLOGY

Germinal Centers

(2012) Gabriel D. Victora et al.   Annual Review of Immunology

CD4 T follicular helper cell dynamics during SIV infection

(2012) Constantinos Petrovas et al.   JOURNAL OF CLINICAL INVESTIGATION

Appion: An integrated, database-driven pipeline to facilitate EM image processing

(2009) Gabriel C. Lander et al.   JOURNAL OF STRUCTURAL BIOLOGY