SARS-CoV-2 infection generates tissue-localized immunological memory in humans

Adaptive immunity to SARS-CoV-2 and COVID-19

(2021) Alessandro Sette et al.   CELL

Evolution of antibody immunity to SARS-CoV-2

(2021) Christian Gaebler et al.   NATURE

Immunological memory to SARS-CoV-2 assessed for up to 8 months after infection

(2021) Jennifer M. Dan et al.   SCIENCE

Longitudinal profiling of respiratory and systemic immune responses reveals myeloid cell-driven lung inflammation in severe COVID-19

(2021) Peter A. Szabo et al.   IMMUNITY

Persistent cellular immunity to SARS-CoV-2 infection

(2021) Gaëlle Breton et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Robust SARS-CoV-2-specific T cell immunity is maintained at 6 months following primary infection

(2021) Jianmin Zuo et al.   NATURE IMMUNOLOGY

Resistance of SARS-CoV-2 variants to neutralization by monoclonal and serum-derived polyclonal antibodies

(2021) Rita E. Chen et al.   NATURE MEDICINE

Prolonged evolution of the human B cell response to SARS-CoV-2 infection

(2021) Mrunal Sakharkar et al.   Science Immunology

N-terminal domain antigenic mapping reveals a site of vulnerability for SARS-CoV-2

(2021) Matthew McCallum et al.   CELL

Tissue-specific immunity for a changing world

(2021) Stuart P. Weisberg et al.   CELL

Neutralizing antibody levels are highly predictive of immune protection from symptomatic SARS-CoV-2 infection

(2021) David S. Khoury et al.   NATURE MEDICINE

Effectiveness of the BNT162b2 Covid-19 Vaccine against the B.1.1.7 and B.1.351 Variants

(2021) Laith J. Abu-Raddad et al.   NEW ENGLAND JOURNAL OF MEDICINE

New SARS-CoV-2 Variants — Clinical, Public Health, and Vaccine Implications

(2021) Salim S. Abdool Karim et al.   NEW ENGLAND JOURNAL OF MEDICINE

Genomics and epidemiology of the P.1 SARS-CoV-2 lineage in Manaus, Brazil

(2021) Nuno R. Faria et al.   SCIENCE

T cell and antibody kinetics delineate SARS-CoV-2 peptides mediating long-term immune responses in COVID-19 convalescent individuals

(2021) Tatjana Bilich et al.   Science Translational Medicine

Tissues, not blood, are where immune cells function

(2021) Donna L. Farber   NATURE

SARS-CoV-2 infection induces long-lived bone marrow plasma cells in humans

(2021) Jackson S. Turner et al.   NATURE

Naturally enhanced neutralizing breadth against SARS-CoV-2 one year after infection

(2021) Zijun Wang et al.   NATURE

Evidence for antibody as a protective correlate for COVID-19 vaccines

(2021) Kristen A. Earle et al.   VACCINE

Peripheral and lung resident memory T cell responses against SARS-CoV-2

(2021) Judith Grau-Expósito et al.   Nature Communications

Single-cell BCR and transcriptome analysis after influenza infection reveals spatiotemporal dynamics of antigen-specific B cells

(2021) Nimitha R. Mathew et al.   Cell Reports

SARS-CoV-2-specific circulating T follicular helper cells correlate with neutralizing antibodies and increase during early convalescence

(2021) Sushma Boppana et al.   PLoS Pathogens

Tissue Determinants of Human NK Cell Development, Function, and Residence

(2020) Pranay Dogra et al.   CELL

Targets of T Cell Responses to SARS-CoV-2 Coronavirus in Humans with COVID-19 Disease and Unexposed Individuals

(2020) Alba Grifoni et al.   CELL

Single-cell landscape of bronchoalveolar immune cells in patients with COVID-19

(2020) Mingfeng Liao et al.   NATURE MEDICINE

Characteristics of pediatric SARS-CoV-2 infection and potential evidence for persistent fecal viral shedding

(2020) Yi Xu et al.   NATURE MEDICINE

Comprehensive analyses of B cell compartments across the human body reveal novel subsets and a gut resident memory phenotype

(2020) Nadine Marianne Weisel et al.   BLOOD

Phenotype and kinetics of SARS-CoV-2-specific T cells in COVID-19 patients with acute respiratory distress syndrome

(2020) Daniela Weiskopf et al.   Science Immunology

Loss of Bcl-6-Expressing T Follicular Helper Cells and Germinal Centers in COVID-19

(2020) Naoki Kaneko et al.   CELL

Antigen-Specific Adaptive Immunity to SARS-CoV-2 in Acute COVID-19 and Associations with Age and Disease Severity

(2020) Carolyn Rydyznski Moderbacher et al.   CELL

Influenza infection fortifies local lymph nodes to promote lung-resident heterosubtypic immunity

(2020) Daniel H. Paik et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Humoral Immune Response to SARS-CoV-2 in Iceland

(2020) Daniel F. Gudbjartsson et al.   NEW ENGLAND JOURNAL OF MEDICINE

Functional SARS-CoV-2-Specific Immune Memory Persists after Mild COVID-19

(2020) Lauren B. Rodda et al.   CELL

Anti-viral protective capacity of tissue resident memory T cells

(2020) Daniel H Paik et al.   Current Opinion in Virology

Tissue-Resident T Cells and Other Resident Leukocytes

(2019) David Masopust et al.   Annual Review of Immunology

T Follicular Helper Cell Biology: A Decade of Discovery and Diseases

(2019) Shane Crotty   IMMUNITY

Location, location, location: Tissue resident memory T cells in mice and humans

(2019) Peter A. Szabo et al.   Science Immunology

Single-cell transcriptomics of human T cells reveals tissue and activation signatures in health and disease

(2019) Peter A. Szabo et al.   Nature Communications

Human T Cell Development, Localization, and Function throughout Life

(2018) Brahma V. Kumar et al.   IMMUNITY

Human Lymph Nodes Maintain TCF-1hiMemory T Cells with High Functional Potential and Clonal Diversity throughout Life

(2018) Michelle Miron et al.   JOURNAL OF IMMUNOLOGY

Microanatomical dissection of human intestinal T-cell immunity reveals site-specific changes in gut-associated lymphoid tissues over life

(2018) Takashi Senda et al.   Mucosal Immunology

The establishment of resident memory B cells in the lung requires local antigen encounter

(2018) S. Rameeza Allie et al.   NATURE IMMUNOLOGY

Dendritic Cells Display Subset and Tissue-Specific Maturation Dynamics over Human Life

(2017) Tomer Granot et al.   IMMUNITY

Comparative analysis of activation induced marker (AIM) assays for sensitive identification of antigen-specific CD4 T cells

(2017) Samantha Reiss et al.   PLoS One

Airway Memory CD4 + T Cells Mediate Protective Immunity against Emerging Respiratory Coronaviruses

(2016) Jincun Zhao et al.   IMMUNITY

A Cytokine-Independent Approach To Identify Antigen-Specific Human Germinal Center T Follicular Helper Cells and Rare Antigen-Specific CD4+T Cells in Blood

(2016) Jennifer M. Dan et al.   JOURNAL OF IMMUNOLOGY

Cytokine-Independent Detection of Antigen-Specific Germinal Center T Follicular Helper Cells in Immunized Nonhuman Primates Using a Live Cell Activation-Induced Marker Technique

(2016) Colin Havenar-Daughton et al.   JOURNAL OF IMMUNOLOGY

Spatial Map of Human T Cell Compartmentalization and Maintenance over Decades of Life

(2014) Joseph J.C. Thome et al.   CELL

Lung-resident memory CD8 T cells (TRM ) are indispensable for optimal cross-protection against pulmonary virus infection

(2013) Tao Wu et al.   JOURNAL OF LEUKOCYTE BIOLOGY

The Juvenile Diabetes Research Foundation Network for Pancreatic Organ Donors with Diabetes (nPOD) Program: goals, operational model and emerging findings

(2013) Alberto Pugliese et al.   PEDIATRIC DIABETES

Germinal Centers

(2012) Gabriel D. Victora et al.   Annual Review of Immunology

Distribution and Compartmentalization of Human Circulating and Tissue-Resident Memory T Cell Subsets

(2012) Taheri Sathaliyawala et al.   IMMUNITY

Roles of BCL6 in normal and transformed germinal center B cells

(2012) Katia Basso et al.   IMMUNOLOGICAL REVIEWS

Follicular Helper CD4 T Cells (TFH)

(2011) Shane Crotty   Annual Review of Immunology

Cutting Edge: Tissue-Retentive Lung Memory CD4 T Cells Mediate Optimal Protection to Respiratory Virus Infection

(2011) J. R. Teijaro et al.   JOURNAL OF IMMUNOLOGY

Effector T cells control lung inflammation during acute influenza virus infection by producing IL-10

(2009) Jie Sun et al.   NATURE MEDICINE

A bicomponent Plasmodium falciparum investigational vaccine composed of protein-peptide conjugates

(2009) J. Kubler-Kielb et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA