Regioselective Synthesis of 5-Trifluoromethyl 1,2,4-Triazoles via [3 + 2]-Cycloaddition of Nitrile Imines with CF3CN

Copper‐Catalyzed Decarbonylative Cyclization of Isatins and Trifluoroacetimidohydrazides for the Synthesis of 2‐(5‐Trifluoromethyl‐1,2,4‐triazol‐3‐yl)anilines

(2022) Yu Zhang et al.   ADVANCED SYNTHESIS & CATALYSIS

Recent advances in the synthesis of fluoroalkylated compounds using fluoroalkyl anhydrides

(2022) Wei Wu et al.   CHINESE CHEMICAL LETTERS

Synthesis of 3-Trifluoromethyl-1,2,4-triazolines and 1,2,4-Triazoles via Tandem Addition/Cyclization of Trifluoromethyl N-Acylhydrazones with Cyanamide

(2022) Xiaoling Liu et al.   JOURNAL OF ORGANIC CHEMISTRY

2,2,2-Trifluoroacetaldehyde O-(Aryl)oxime: A Precursor of Trifluoroacetonitrile

(2022) Bo Lin et al.   ORGANIC LETTERS

An overview of nitrile imine based [3+2] cycloadditions over half a decade

(2022) Ani Deepthi et al.   TETRAHEDRON

Regioselective Synthesis of 5-Trifluoromethylpyrazoles by [3 + 2] Cycloaddition of Nitrile Imines and 2-Bromo-3,3,3-trifluoropropene

(2021) Hao Zeng et al.   JOURNAL OF ORGANIC CHEMISTRY

Palladium-Catalyzed Cascade Carbonylative Synthesis of 1,2,4-Triazol-3-ones from Hydrazonoyl Chlorides and NaN3

(2021) Shiying Du et al.   ORGANIC LETTERS

Recent Advances in the Generation of Nitrilium Betaine 1,3-Dipoles

(2021) Craig Jamieson et al.   SYNTHESIS-STUTTGART

1,2,4-Triazoles as Important Antibacterial Agents

(2021) Małgorzata Strzelecka et al.   Pharmaceuticals

Synthesis of 5‐Trifluoromethyl‐1,2,4‐Triazoles via Metal‐Free Annulation of Trifluoroacetimidohydrazides and Methyl Ketones

(2021) Jiajun Zhang et al.   ADVANCED SYNTHESIS & CATALYSIS

High Thermal Stability and Insensitive Fused Triazole-Triazine Trifluoromethyl-Containing Explosives (TFX)

(2021) Zhengfeng Yan et al.   ACS Omega

Oxidative Cyclization of Trifluoroacetimidohydrazides with D‐Glucose for the Metal‐Free Synthesis of 3‐Trifluoromethyl‐1,2,4‐Triazoles

(2021) Shu‐Ning Lu et al.   ADVANCED SYNTHESIS & CATALYSIS

Elemental Sulfur and Dimethyl Sulfoxide‐Promoted Oxidative Cyclization of Trifluoroacetimidohydrazides with Methylhetarenes for the Synthesis of 3‐Hetaryl ‐5‐trifluoromethyl‐1,2,4‐triazoles

(2021) Jiajun Zhang et al.   CHINESE JOURNAL OF CHEMISTRY

Cu‐Catalysed Three‐Component Reaction of Aryldiazonium Salts with Fluorinated Diazo Reagents and Nitriles: Access to Difluoro‐ and Trifluoromethylated N1‐Aryl‐1,2,4‐triazoles

(2020) Xing Peng et al.   ADVANCED SYNTHESIS & CATALYSIS

A Convenient FeCl 3 ‐Mediated Synthesis of 5‐Trifluoromethyl‐1,2,4‐triazoles from Trifluoroacetimidoyl Chlorides and Hydrazides

(2020) Shiying Du et al.   ADVANCED SYNTHESIS & CATALYSIS

Metal‐Free Synthesis of 5‐Trifluoromethyl‐1,2,4‐Triazoles from Iodine‐Mediated Annulation of Trifluoroacetimidoyl Chlorides and Hydrazones

(2019) Sipei Hu et al.   ADVANCED SYNTHESIS & CATALYSIS

Intramolecular oxidative cyclization of N-(2,2,2-trifluoro-1-(phenylimino)ethyl)benzimidamide

(2019) Elham Kazemi et al.   MOLECULAR DIVERSITY

Deconstructive Oxygenation of Unstrained Cycloalkanamines

(2019) Jian-Wu Zhang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Improved synthesis of perfluoroalkyl substituted 1,3,4-oxadiazoles as precursors for corresponding 1,2,4-triazoles

(2016) Mariano Grünebaum et al.   JOURNAL OF FLUORINE CHEMISTRY

Applications of Fluorine in Medicinal Chemistry

(2015) Eric P. Gillis et al.   JOURNAL OF MEDICINAL CHEMISTRY

Sitagliptin: A Review of Its Use in Patients with Type 2 Diabetes Mellitus

(2014) Greg L. Plosker   DRUGS

Fluorine in Pharmaceutical Industry: Fluorine-Containing Drugs Introduced to the Market in the Last Decade (2001–2011)

(2013) Jiang Wang et al.   CHEMICAL REVIEWS

Recent Researches in Triazole Compounds as Medicinal Drugs

(2012) C. -H. Zhou et al.   CURRENT MEDICINAL CHEMISTRY

Advances in synthetic approach to and antifungal activity of triazoles

(2011) Kumari Shalini et al.   Beilstein Journal of Organic Chemistry

Novel Synthetic Approaches to (Trifluoromethyl)triazoles

(2010) Pavel Mykhailiuk et al.   SYNTHESIS-STUTTGART

The Many Roles for Fluorine in Medicinal Chemistry

(2008) William K. Hagmann   JOURNAL OF MEDICINAL CHEMISTRY