Design and Synthesis of New α-hydroxy β-fluoro/β-trifluoromethyl and Unsaturated Phosphonates from Carbohydrate-Derived Building Blocks via Pudovik and Horner–Wadsworth–Emmons Reactions

Applications of the Horner-Wadsworth-Emmons olefination in modern natural product synthesis

(2021) Dávid Roman et al.   SYNTHESIS-STUTTGART

Probing cytochrome P450 (CYP) bioactivation with chloromethylindoline bioprecursors derived from the duocarmycin family of compounds

(2021) Natalia Ortuzar et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Emerging building blocks for medicinal chemistry: recent synthetic advances

(2021) Oleksandr O Grygorenko et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

Synthesis of Fluorinated Amides Starting from Carbohydrates Based on the Claisen Rearrangement

(2021) Monika Bilska‐Markowska et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

Tetraalkyl Hydroxymethylene-bisphosphonate and Dialkyl 1-Diphenylphosphinoyl-1-hydroxy-ethylphosphonate Derivatives by the Pudovik Reaction and Their Rearranged Products

(2021) Zsuzsanna Szalai et al.   MOLECULES

Efficient synthesis of dipeptide analogues of α-fluorinated β-aminophosphonates

(2020) Marcin Kaźmierczak et al.   Beilstein Journal of Organic Chemistry

Fluorine-containing drugs approved by the FDA in 2019

(2020) Haibo Mei et al.   CHINESE CHEMICAL LETTERS

Metabolic and Pharmaceutical Aspects of Fluorinated Compounds

(2020) Benjamin M. Johnson et al.   JOURNAL OF MEDICINAL CHEMISTRY

Application of α-Amino-β-fluorophosphonates in Construction of their Dipeptide Analogues

(2020) Marcin Kaźmierczak et al.   SYNTHESIS-STUTTGART

Fluorinated peptide biomaterials

(2020) Janna N. Sloand et al.   Peptide Science

Post‐Assembly Photomasking of Potassium Acyltrifluoroborates (KATs) for Two‐Photon 3D Patterning of PEG‐Hydrogels

(2020) Haewon Song et al.   HELVETICA CHIMICA ACTA

α-Hydroxyphosphonates as versatile starting materials

(2019) Zita Rádai   PHOSPHORUS SULFUR AND SILICON AND THE RELATED ELEMENTS

Design, properties and applications of fluorinated and fluoroalkylated N-containing monosaccharides and their analogues

(2019) Monika Bilska-Markowska et al.   JOURNAL OF FLUORINE CHEMISTRY

Regioselective Fluorination of α-Hydroxy-β-aminophosphonates by Using PyFluor

(2018) Marcin Kaźmierczak et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

Fluorine and Fluorinated Motifs in the Design and Application of Bioisosteres for Drug Design

(2018) Nicholas A. Meanwell   JOURNAL OF MEDICINAL CHEMISTRY

Synthesis and Reactions of α-Hydroxyphosphonates

(2018) Zita Rádai et al.   MOLECULES

Recent topics of the natural product synthesis by Horner–Wadsworth–Emmons reaction

(2018) Kenichi Kobayashi et al.   TETRAHEDRON LETTERS

Absolute and relative pKa predictions via a DFT approach applied to the SAMPL6 blind challenge

(2018) Qiao Zeng et al.   JOURNAL OF COMPUTER-AIDED MOLECULAR DESIGN

Latest achievements in the preparation of fluorinated aminophosphonates and aminophosphonic acids

(2017) Tomasz Cytlak et al.   PHOSPHORUS SULFUR AND SILICON AND THE RELATED ELEMENTS

Synthesis of Fluorine-Containing Analogues of 1-Lysoglycerophospholipids via Horner–Wadsworth–Emmons Reaction

(2017) Shigeki Sano et al.   SYNTHESIS-STUTTGART

Facile synthesis of fluorovinyl-containing lactams via ring-closing metathesis of N -substituted 2-fluoroallylamides

(2016) Yang Li et al.   TETRAHEDRON

Applications of Fluorine in Medicinal Chemistry

(2015) Eric P. Gillis et al.   JOURNAL OF MEDICINAL CHEMISTRY

Combining a Clostridial Enzyme Exhibiting Unusual Active Site Plasticity with a Remarkably Facile Sigmatropic Rearrangement: Rapid, Stereocontrolled Entry into Densely Functionalized Fluorinated Phosphonates for Chemical Biology

(2015) Kaushik Panigrahi et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Preparation and characterization of α-fluorinated-γ-aminophosphonates

(2014) Marcin Kaźmierczak et al.   JOURNAL OF FLUORINE CHEMISTRY

A convenient synthesis of fluorinated vinyl ethers derived from di-O-isopropylidenehexofuranose and O-isopropylidenepentofuranose

(2014) Bartosz Marciniak et al.   JOURNAL OF FLUORINE CHEMISTRY

Fluorine in Pharmaceutical Industry: Fluorine-Containing Drugs Introduced to the Market in the Last Decade (2001–2011)

(2013) Jiang Wang et al.   CHEMICAL REVIEWS

Recent advances in the synthesis of fluorinated aminophosphonates and aminophosphonic acids

(2013) Kostiantyn V. Turcheniuk et al.   RSC Advances

Fluorine local environment: from screening to drug design

(2012) Anna Vulpetti et al.   DRUG DISCOVERY TODAY

Synthesis and applications of fluorinated nucleoside analogues

(2012) Hanna Wójtowicz-Rajchel   JOURNAL OF FLUORINE CHEMISTRY

DAST mediated preparation of β-fluoro-α-aminophosphonates

(2012) Marcin Kaźmierczak et al.   JOURNAL OF FLUORINE CHEMISTRY

Fluorine: A new element in protein design

(2012) Benjamin C. Buer et al.   PROTEIN SCIENCE

The use of phosphate bioisosteres in medicinal chemistry and chemical biology

(2012) Thomas S. Elliott et al.   MedChemComm

Fluorine Conformational Effects in Organocatalysis: An Emerging Strategy for Molecular Design

(2011) Lucie E. Zimmer et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Stereoselective Synthesis of (E)-α-Fluorovinylphosphonates from α,α-Difluorophosphonates

(2011) Petr Beier et al.   SYNLETT

Organocatalytic enantioselective synthesis of quinolizidine alkaloids (+)-myrtine, (−)-lupinine, and (+)-epiepiquinamide

(2011) Santos Fustero et al.   TETRAHEDRON

Rasta Resin-PPh3 and its Use in Chromatography-Free Wittig Reactions

(2010) Patrick Toy et al.   SYNLETT

Fluorine in medicinal chemistry: a century of progress and a 60-year retrospective of selected highlights

(2009) Robert Filler et al.   Future Medicinal Chemistry

Fluoroolefins as amide bond mimics in dipeptidyl peptidase IV inhibitors

(2008) Scott D. Edmondson et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Identification of KD5170: A novel mercaptoketone-based histone deacetylase inhibitor

(2008) Joseph E. Payne et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

α- and β-Substituted phosphonate analogs of LPA as autotaxin inhibitors

(2007) Peng Cui et al.   BIOORGANIC & MEDICINAL CHEMISTRY