Tissue-specific Grb10/Ddc insulator drives allelic architecture for cardiac development

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(2021) Elisia D. Tichy et al.   Cell Reports

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The role of CTCF in the organization of the centromeric 11p15 imprinted domain interactome

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(2021) Adam R. Prickett et al.   Frontiers in Cell and Developmental Biology

Diverse epigenetic mechanisms maintain parental imprints within the embryonic and extraembryonic lineages

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Sequential in cis mutagenesis in vivo reveals various functions for CTCF sites at the mouse HoxD cluster

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(2020) Amanda Khoury et al.   Nature Communications

Genome-wide association and Mendelian randomisation analysis provide insights into the pathogenesis of heart failure

(2020) Sonia Shah et al.   Nature Communications

Resolving the 3D Landscape of Transcription-Linked Mammalian Chromatin Folding

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Phenotypic Refinement of Heart Failure in a National Biobank Facilitates Genetic Discovery

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Genomic Imprinting and Physiological Processes in Mammals

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Detailed analysis of paternal knockout Grb10 mice suggests effects on stability of social behavior, rather than social dominance

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Hemimethylation of CpG dyads is characteristic of secondary DMRs associated with imprinted loci and correlates with 5-hydroxymethylcytosine at paternally methylated sequences

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Imprinted gene dysregulation in aTet1null mouse model is stochastic and variable in the germline and offspring

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Growing oocyte-specific transcription-dependent de novo DNA methylation at the imprinted Zrsr1-DMR

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Juicebox.js Provides a Cloud-Based Visualization System for Hi-C Data

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Single-nucleus transcriptomic survey of cell diversity and functional maturation in postnatal mammalian hearts

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Asymmetric DNA methylation of CpG dyads is a feature of secondary DMRs associated with the Dlk1/Gtl2 imprinting cluster in mouse

(2017) Megan Guntrum et al.   Epigenetics & Chromatin

GeneHancer: genome-wide integration of enhancers and target genes in GeneCards

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Impulsive choices in mice lacking imprinted Nesp55

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(2016) Emma L. Wakeling et al.   Nature Reviews Endocrinology

FGFR3 gene mutation plus GRB10 gene duplication in a patient with achondroplasia plus growth delay with prenatal onset

(2016) Haiming Yuan et al.   Orphanet Journal of Rare Diseases

Disruptions of Topological Chromatin Domains Cause Pathogenic Rewiring of Gene-Enhancer Interactions

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Pyrosequencing for Accurate Imprinted Allele Expression Analysis

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A Survey of Imprinted Gene Expression in Mouse Trophoblast Stem Cells

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A 3D Map of the Human Genome at Kilobase Resolution Reveals Principles of Chromatin Looping

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Genomic imprinting in development, growth, behavior and stem cells

(2014) Robert N. Plasschaert et al.   DEVELOPMENT

Tissue-specific insulator function at H19/Igf2 revealed by deletions at the imprinting control region

(2014) F. Y. Ideraabdullah et al.   HUMAN MOLECULAR GENETICS

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(2014) Hui Yang et al.   Nature Protocols

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(2014) Jo Peters   NATURE REVIEWS GENETICS

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Tissue-specific regulation and function of Grb10 during growth and neuronal commitment

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(2014) D. P. Barlow et al.   Cold Spring Harbor Perspectives in Biology

Analysis of DNA methylation acquisition at the imprinted Dlk1 locus reveals asymmetry at CpG dyads

(2014) Alyssa Gagne et al.   Epigenetics & Chromatin

Dynamic GATA4 enhancers shape the chromatin landscape central to heart development and disease

(2014) Aibin He et al.   Nature Communications

Possible association between complex congenital heart defects and 11p15 hypomethylation in three patients with severe Silver-Russell syndrome

(2013) Mustafa Ghanim et al.   AMERICAN JOURNAL OF MEDICAL GENETICS PART A

One-Step Generation of Mice Carrying Mutations in Multiple Genes by CRISPR/Cas-Mediated Genome Engineering

(2013) Haoyi Wang et al.   CELL

The ancestor of extant Japanese fancy mice contributed to the mosaic genomes of classical inbred strains

(2013) T. Takada et al.   GENOME RESEARCH

Genome-wide and parental allele-specific analysis of CTCF and cohesin DNA binding in mouse brain reveals a tissue-specific binding pattern and an association with imprinted differentially methylated regions

(2013) A. R. Prickett et al.   GENOME RESEARCH

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(2013) Eric S. Folker et al.   Frontiers in Physiology

The Igf2as Transcript is Exported into Cytoplasm and Associated with Polysomes

(2012) Carolina Duart-Garcia et al.   BIOCHEMICAL GENETICS

Grb10 regulates the development of fiber number in skeletal muscle

(2012) Lowenna J. Holt et al.   FASEB JOURNAL

A unique regulatory phase of DNA methylation in the early mammalian embryo

(2012) Zachary D. Smith et al.   NATURE

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(2012) Johannes Schindelin et al.   NATURE METHODS

Regulation of the dopaminergic system in a murine model of aromatic l-amino acid decarboxylase deficiency

(2012) Ni-Chung Lee et al.   NEUROBIOLOGY OF DISEASE

Non-Coding RNAs at the Gnas and Snrpn-Ube3a Imprinted Gene Loci and Their Involvement in Hereditary Disorders

(2012) Antonius Plagge   Frontiers in Genetics

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Establishment of paternal allele-specific DNA methylation at the imprinted mouseGtl2locus

(2011) Kamila Nowak et al.   Epigenetics

Distinct physiological and behavioural functions for parental alleles of imprinted Grb10

(2011) Alastair S. Garfield et al.   NATURE

Genomic imprinting: the emergence of an epigenetic paradigm

(2011) Anne C. Ferguson-Smith   NATURE REVIEWS GENETICS

Co-occupancy by multiple cardiac transcription factors identifies transcriptional enhancers active in heart

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Transcription Is Required to Establish Maternal Imprinting at the Prader-Willi Syndrome and Angelman Syndrome Locus

(2011) Emily Y. Smith et al.   PLoS Genetics

Tyrosine hydroxylase is expressed during early heart development and is required for cardiac chamber formation

(2010) Carmen López-Sánchez et al.   CARDIOVASCULAR RESEARCH

Transcription is required for establishment of germline methylation marks at imprinted genes

(2009) M. Chotalia et al.   GENES & DEVELOPMENT

Paternal deletion of Meg1/Grb10 DMR causes maternalization of the Meg1/Grb10 cluster in mouse proximal Chromosome 11 leading to severe pre- and postnatal growth retardation

(2009) Hirosuke Shiura et al.   HUMAN MOLECULAR GENETICS

Cohesin Is Required for Higher-Order Chromatin Conformation at the Imprinted IGF2-H19 Locus

(2009) Raffaella Nativio et al.   PLoS Genetics

A Maternal-Zygotic Effect Gene, Zfp57, Maintains Both Maternal and Paternal Imprints

(2008) Xiajun Li et al.   DEVELOPMENTAL CELL

A mono-allelic bivalent chromatin domain controls tissue-specific imprinting at Grb10

(2008) Lionel A Sanz et al.   EMBO JOURNAL

Aromatic l-amino acid decarboxylase deficiency in Taiwan

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Three-dimensional conformation at the H19/Igf2 locus supports a model of enhancer tracking

(2008) N. Engel et al.   HUMAN MOLECULAR GENETICS