Mesenchymal stem cell-derived exosomes in cancer therapy resistance: recent advances and therapeutic potential
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Title
Mesenchymal stem cell-derived exosomes in cancer therapy resistance: recent advances and therapeutic potential
Authors
Keywords
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Journal
Molecular Cancer
Volume 21, Issue 1, Pages -
Publisher
Springer Science and Business Media LLC
Online
2022-09-13
DOI
10.1186/s12943-022-01650-5
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Note: Only part of the references are listed.- Sorting and packaging of RNA into extracellular vesicles shape intracellular transcript levels
- (2022) Tina O’Grady et al. BMC BIOLOGY
- Mouse mesenchymal stem cell-derived exosomal miR-466f-3p reverses EMT process through inhibiting AKT/GSK3β pathway via c-MET in radiation-induced lung injury
- (2022) Yi Li et al. JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH
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- (2022) Hui Zhou et al. Molecular Cancer
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- (2021) Fangyu Chen et al. JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH
- Isolation and characterization of extracellular vesicle subpopulations from tissues
- (2021) Rossella Crescitelli et al. Nature Protocols
- The biology, function, and applications of exosomes in cancer
- (2021) Jinyi Liu et al. Acta Pharmaceutica Sinica B
- Treatment for Hepatocellular Carcinoma Is Enhanced When Norcantharidin Is Encapsulated in Exosomes Derived from Bone Marrow Mesenchymal Stem Cells
- (2021) Leyi Liang et al. MOLECULAR PHARMACEUTICS
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- (2021) Bing Dong et al. Experimental Hematology & Oncology
- Exosomes from BM-MSCs promote acute myeloid leukemia cell proliferation, invasion and chemoresistance via upregulation of S100A4
- (2021) Tianxin Lyu et al. Experimental Hematology & Oncology
- How I Treat Chronic Phase Chronic Myelogenous Leukemia
- (2021) Ellin Berman BLOOD
- Therapeutic roles of mesenchymal stem cell-derived extracellular vesicles in cancer
- (2021) Zhijie Weng et al. Journal of Hematology & Oncology
- Artificial exosomes for translational nanomedicine
- (2021) Yong-Jiang Li et al. JOURNAL OF NANOBIOTECHNOLOGY
- Mesenchymal Stem Cell-Derived Exosomes: Applications in Regenerative Medicine
- (2021) Mangesh D. Hade et al. Cells
- MicroRNA sequence codes for small extracellular vesicle release and cellular retention
- (2021) Ruben Garcia-Martin et al. NATURE
- Mesenchymal stem cells-derived exosomes for drug delivery
- (2021) Yao Sun et al. Stem Cell Research & Therapy
- MSC-Derived Extracellular Vesicles in Tumors and Therapy
- (2021) Tianjiao Luo et al. Cancers
- Cancer statistics, 2020
- (2020) Rebecca L. Siegel et al. CA-A CANCER JOURNAL FOR CLINICIANS
- MiR-199a-modified exosomes from adipose tissue-derived mesenchymal stem cells improve hepatocellular carcinoma chemosensitivity through mTOR pathway
- (2020) Guohua Lou et al. JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH
- Exosomes overexpressing miR-34c inhibit malignant behavior and reverse the radioresistance of nasopharyngeal carcinoma
- (2020) Fang-Zhu Wan et al. Journal of Translational Medicine
- Noncoding RNAs in gastric cancer: implications for drug resistance
- (2020) Ling Wei et al. Molecular Cancer
- Native and bioengineered extracellular vesicles for cardiovascular therapeutics
- (2020) Ricardo Cerqueira de Abreu et al. Nature Reviews Cardiology
- Bioinspired exosome-like therapeutics and delivery nanoplatforms
- (2020) Mei Lu et al. BIOMATERIALS
- Biology and therapeutic potential of mesenchymal stem cell‐derived exosomes
- (2020) Zhou Xunian et al. CANCER SCIENCE
- Bone mesenchymal stem cells are recruited via CXCL8‐CXCR2 and promote EMT through TGF‐β signal pathways in oral squamous carcinoma
- (2020) Lin Meng et al. CELL PROLIFERATION
- Exosomal microRNA‑146a derived from mesenchymal stem cells increases the sensitivity of ovarian cancer cells to docetaxel and taxane via a LAMC2‑mediated PI3K/Akt axis
- (2020) Liya Qiu et al. INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE
- Cancer cell-derived exosomal circUHRF1 induces natural killer cell exhaustion and may cause resistance to anti-PD1 therapy in hepatocellular carcinoma
- (2020) Peng-Fei Zhang et al. Molecular Cancer
- Integrating evolutionary dynamics into cancer therapy
- (2020) Robert A. Gatenby et al. Nature Reviews Clinical Oncology
- Role and Mechanisms of Exosomal miRNAs in IBD Pathophysiology
- (2020) Sameena Wani et al. AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY
- Inhibiting the inhibitors: Targeting anti-apoptotic proteins in cancer and therapy resistance
- (2020) Nir Shahar et al. DRUG RESISTANCE UPDATES
- Challenges in the development and establishment of exosome-based drug delivery systems
- (2020) Jin Wang et al. JOURNAL OF CONTROLLED RELEASE
- Bone marrow mesenchymal stem cells-derived exosomal microRNA-193a reduces cisplatin resistance of non-small cell lung cancer cells via targeting LRRC1
- (2020) Hongbo Wu et al. Cell Death & Disease
- Adipose Mesenchymal Stem Cell-Derived Exosomal microRNA-1236 Reduces Resistance of Breast Cancer Cells to Cisplatin by Suppressing SLC9A1 and the Wnt/β-Catenin Signaling
- (2020) Zhongming Jia et al. Cancer Management and Research
- Mesenchymal stem cells-secreted exosome promotes chemoresistance in breast cancer via enhancing miR-21-5p-mediated S100A6 expression
- (2020) Tao Luo et al. Molecular Therapy-Oncolytics
- Exosomal Formulation Escalates Cellular Uptake of Honokiol Leading to the Enhancement of Its Antitumor Efficacy
- (2020) Rajashekhar Kanchanapally et al. ACS Omega
- Pancreatic cancer-targeting exosomes for enhancing immunotherapy and reprogramming tumor microenvironment
- (2020) Wenxi Zhou et al. BIOMATERIALS
- Human umbilical cord mesenchymal stem cells-derived exosomal microRNA-451a represses epithelial–mesenchymal transition of hepatocellular carcinoma cells by inhibiting ADAM10.
- (2020) Yunxiuxiu Xu et al. RNA Biology
- Exosome-Transmitted PSMA3 and PSMA3-AS1 Promotes Proteasome Inhibitors Resistance in Multiple Myeloma
- (2019) Hongxia Xu et al. CLINICAL CANCER RESEARCH
- BM-MSC-derived exosomes alleviate radiation-induced bone loss by restoring the function of recipient BM-MSCs and activating Wnt/β-catenin signaling
- (2019) Rui Zuo et al. Stem Cell Research & Therapy
- Radiotherapy toxicity
- (2019) Dirk De Ruysscher et al. Nature Reviews Disease Primers
- Navigating metabolic pathways to enhance antitumour immunity and immunotherapy
- (2019) Xiaoyun Li et al. Nature Reviews Clinical Oncology
- Exosomes in the tumor microenvironment as mediators of cancer therapy resistance
- (2019) Irene Li et al. Molecular Cancer
- Mesenchymal stem cell exosomes: a two-edged sword in cancer therapy
- (2019) Faezeh Vakhshiteh et al. International Journal of Nanomedicine
- Exosomes: composition, biogenesis, and mechanisms in cancer metastasis and drug resistance
- (2019) Ladan Mashouri et al. Molecular Cancer
- Exosomal tRNA-derived small RNA as a promising biomarker for cancer diagnosis
- (2019) Lei Zhu et al. Molecular Cancer
- Cisplatin: The first metal based anticancer drug
- (2019) Sumit Ghosh BIOORGANIC CHEMISTRY
- Human bone marrow-derived mesenchymal stem cell-secreted exosomes overexpressing microRNA-34a ameliorate glioblastoma development via down-regulating MYCN
- (2019) Bin Wang et al. CELLULAR ONCOLOGY
- Taxol-Loaded MSC-Derived Exosomes Provide a Therapeutic Vehicle to Target Metastatic Breast Cancer and Other Carcinoma Cells
- (2019) Catharina Melzer et al. Cancers
- Exosomes derived from microRNA-199a-overexpressing mesenchymal stem cells inhibit glioma progression by down-regulating AGAP2
- (2019) Lei Yu et al. Aging-US
- Macrophages Educated with Exosomes from Primed Mesenchymal Stem Cells Treat Acute Radiation Syndrome by Promoting Hematopoietic Recovery
- (2019) John A. Kink et al. BIOLOGY OF BLOOD AND MARROW TRANSPLANTATION
- Exosomes in Cancer Radioresistance
- (2019) Jie Ni et al. Frontiers in Oncology
- A Nanodrug Consisting Of Doxorubicin And Exosome Derived From Mesenchymal Stem Cells For Osteosarcoma Treatment In Vitro
- (2019) Hongxiang Wei et al. International Journal of Nanomedicine
- Exosomes Produced by Mesenchymal Stem Cells Drive Differentiation of Myeloid Cells into Immunosuppressive M2-Polarized Macrophages in Breast Cancer
- (2019) Subir Biswas et al. JOURNAL OF IMMUNOLOGY
- A view on drug resistance in cancer
- (2019) Neil Vasan et al. NATURE
- The many functions of ESCRTs
- (2019) Marina Vietri et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Bone marrow mesenchymal stem cells-derived exosomes for penetrating and targeted chemotherapy of pancreatic cancer
- (2019) Yu Zhou et al. Acta Pharmaceutica Sinica B
- The application of mesenchymal stem cells to treat thermal and radiation burns
- (2018) Kathleen Rodgers et al. ADVANCED DRUG DELIVERY REVIEWS
- Exosomes from mesenchymal stromal cells enhance imatinib-induced apoptosis in human leukemia cells via activation of caspase signaling pathway
- (2018) Ying Liu et al. CYTOTHERAPY
- Molecular targeted therapy: treating cancer with specificity
- (2018) Yeuan Ting Lee et al. EUROPEAN JOURNAL OF PHARMACOLOGY
- Identification of RNA-binding proteins in exosomes capable of interacting with different types of RNA: RBP-facilitated transport of RNAs into exosomes
- (2018) Luisa Statello et al. PLoS One
- Honokiol: An anticancer lignan
- (2018) Abdur Rauf et al. BIOMEDICINE & PHARMACOTHERAPY
- Exosomes derived from mesenchymal stem cells enhance radiotherapy-induced cell death in tumor and metastatic tumor foci
- (2018) Virgínea de Araujo Farias et al. Molecular Cancer
- Hsp90 Mediates Membrane Deformation and Exosome Release
- (2018) Elsa Lauwers et al. MOLECULAR CELL
- A New Approach for Loading Anticancer Drugs Into Mesenchymal Stem Cell-Derived Exosome Mimetics for Cancer Therapy
- (2018) Senthilkumar Kalimuthu et al. Frontiers in Pharmacology
- Specificities of secretion and uptake of exosomes and other extracellular vesicles for cell-to-cell communication
- (2018) Mathilde Mathieu et al. NATURE CELL BIOLOGY
- EVmiRNA: a database of miRNA profiling in extracellular vesicles
- (2018) Teng Liu et al. NUCLEIC ACIDS RESEARCH
- Exosomes derived from siRNA against GRP78 modified bone-marrow-derived mesenchymal stem cells suppress Sorafenib resistance in hepatocellular carcinoma
- (2018) Hongdan Li et al. JOURNAL OF NANOBIOTECHNOLOGY
- DNA-Containing Exosomes Derived from Cancer Cells Treated with Topotecan Activate a STING-Dependent Pathway and Reinforce Antitumor Immunity
- (2017) Yuichi Kitai et al. JOURNAL OF IMMUNOLOGY
- Mesenchymal stem cells: key players in cancer progression
- (2017) Sarah M. Ridge et al. Molecular Cancer
- Isolation of exosomes from whole blood by integrating acoustics and microfluidics
- (2017) Mengxi Wu et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Mismatch repair deficiency predicts response of solid tumors to PD-1 blockade
- (2017) Dung T. Le et al. SCIENCE
- Delivery of Exogenous miR-124 to Glioblastoma Multiform Cells by Wharton’s Jelly Mesenchymal Stem Cells Decreases Cell Proliferation and Migration, and Confers Chemosensitivity
- (2017) S. Sharif et al. Stem Cell Reviews and Reports
- Mesenchymal stem cells release exosomes that transfer miRNAs to endothelial cells and promote angiogenesis
- (2017) Min Gong et al. Oncotarget
- Progress in Exosome Isolation Techniques
- (2017) Pin Li et al. Theranostics
- Recruitment dynamics of ESCRT-III and Vps4 to endosomes and implications for reverse membrane budding
- (2017) Manuel Alonso Y Adell et al. eLife
- Delivery of Exogenous miR-124 to Glioblastoma Multiform Cells by Wharton’s Jelly Mesenchymal Stem Cells Decreases Cell Proliferation and Migration, and Confers Chemosensitivity
- (2017) S. Sharif et al. Stem Cell Reviews and Reports
- Exosomes: Fundamental Biology and Roles in Cardiovascular Physiology
- (2016) Ahmed Ibrahim et al. Annual Review of Physiology
- Mesenchymal Stem Cell–Derived Exosomes Stimulate Cycling Quiescence and Early Breast Cancer Dormancy in Bone Marrow
- (2016) Sarah A. Bliss et al. CANCER RESEARCH
- The Endosome-associated Deubiquitinating Enzyme USP8 Regulates BACE1 Enzyme Ubiquitination and Degradation
- (2016) Eniola Funmilayo Aduke Yeates et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- The biology and function of exosomes in cancer
- (2016) Raghu Kalluri JOURNAL OF CLINICAL INVESTIGATION
- ExoCarta: A Web-Based Compendium of Exosomal Cargo
- (2016) Shivakumar Keerthikumar et al. JOURNAL OF MOLECULAR BIOLOGY
- Mesenchymal stromal cell-derived extracellular vesicles rescue radiation damage to murine marrow hematopoietic cells
- (2016) S Wen et al. LEUKEMIA
- Clonal neoantigens elicit T cell immunoreactivity and sensitivity to immune checkpoint blockade
- (2016) N. McGranahan et al. SCIENCE
- ExtraPEG: A Polyethylene Glycol-Based Method for Enrichment of Extracellular Vesicles
- (2016) Mark A. Rider et al. Scientific Reports
- Alterations in acute myeloid leukaemia bone marrow stromal cell exosome content coincide with gains in tyrosine kinase inhibitor resistance
- (2015) Shelton Viola et al. BRITISH JOURNAL OF HAEMATOLOGY
- Exosomes derived from human mesenchymal stem cells confer drug resistance in gastric cancer
- (2015) Runbi Ji et al. CELL CYCLE
- Human Umbilical Cord Mesenchymal Stem Cells: A New Era for Stem Cell Therapy
- (2015) Dah-Ching Ding et al. CELL TRANSPLANTATION
- Human Umbilical Cord Mesenchymal Stem Cells Promote Breast Cancer Metastasis by Interleukin-8- and Interleukin-6-Dependent Induction of CD44+/CD24- Cells
- (2015) Fengxia Ma et al. CELL TRANSPLANTATION
- Human umbilical cord mesenchymal stem cells: an overview of their potential in cell-based therapy
- (2015) Tan Li et al. EXPERT OPINION ON BIOLOGICAL THERAPY
- Acquisition of new tumor cell properties by MSC-derived exosomes
- (2015) YUANYUAN YANG et al. INTERNATIONAL JOURNAL OF ONCOLOGY
- Exosomes derived from miR-122-modified adipose tissue-derived MSCs increase chemosensitivity of hepatocellular carcinoma
- (2015) Guohua Lou et al. Journal of Hematology & Oncology
- Mesenchymal Stem Cell-derived Extracellular Vesicles: Toward Cell-free Therapeutic Applications
- (2015) Sweta Rani et al. MOLECULAR THERAPY
- Opportunities and challenges of radiotherapy for treating cancer
- (2015) Dörthe Schaue et al. Nature Reviews Clinical Oncology
- Human Umbilical Cord Matrix Mesenchymal Stem Cells Suppress the Growth of Breast Cancer by Expression of Tumor Suppressor Genes
- (2015) Naomi Ohta et al. PLoS One
- Mesenchymal stem cell exosomes
- (2015) Ruenn Chai Lai et al. SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY
- Identification of Double-stranded Genomic DNA Spanning All Chromosomes with MutatedKRASandp53DNA in the Serum Exosomes of Patients with Pancreatic Cancer
- (2014) Christoph Kahlert et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Paclitaxel is incorporated by mesenchymal stromal cells and released in exosomes that inhibit in vitro tumor growth: A new approach for drug delivery
- (2014) Luisa Pascucci et al. JOURNAL OF CONTROLLED RELEASE
- Estimating the demand for radiotherapy from the evidence: A review of changes from 2003 to 2012
- (2014) Michael B. Barton et al. RADIOTHERAPY AND ONCOLOGY
- Exosomes from bone marrow mesenchymal stem cells contain a microRNA that promotes dormancy in metastatic breast cancer cells
- (2014) M. Ono et al. Science Signaling
- Endogenous RNAs Modulate MicroRNA Sorting to Exosomes and Transfer to Acceptor Cells
- (2014) Mario Leonardo Squadrito et al. Cell Reports
- Exosomes in cancer development, metastasis, and drug resistance: a comprehensive review
- (2013) Asfar S. Azmi et al. CANCER AND METASTASIS REVIEWS
- Signaling Pathways in Exosomes Biogenesis, Secretion and Fate
- (2013) Lorena Urbanelli et al. Genes
- Delivery of Functional Anti-miR-9 by Mesenchymal Stem Cell–derived Exosomes to Glioblastoma Multiforme Cells Conferred Chemosensitivity
- (2013) Jessian L Munoz et al. Molecular Therapy-Nucleic Acids
- Mesenchymal stem cell: An efficient mass producer of exosomes for drug delivery
- (2012) Ronne Wee Yeh Yeo et al. ADVANCED DRUG DELIVERY REVIEWS
- Governance of Endocytic Trafficking and Signaling by Reversible Ubiquitylation
- (2012) Michael J. Clague et al. DEVELOPMENTAL CELL
- Systemically Injected Exosomes Targeted to EGFR Deliver Antitumor MicroRNA to Breast Cancer Cells
- (2012) Shin-ichiro Ohno et al. MOLECULAR THERAPY
- Multivesicular Body Morphogenesis
- (2011) Phyllis I. Hanson et al. Annual Review of Cell and Developmental Biology
- Exosomes as intercellular signalosomes and pharmacological effectors
- (2011) Michel Record et al. BIOCHEMICAL PHARMACOLOGY
- UBAP1 Is a Component of an Endosome-Specific ESCRT-I Complex that Is Essential for MVB Sorting
- (2011) Flavia Stefani et al. CURRENT BIOLOGY
- The ESCRT Pathway
- (2011) William M. Henne et al. DEVELOPMENTAL CELL
- Delivery of siRNA to the mouse brain by systemic injection of targeted exosomes
- (2011) Lydia Alvarez-Erviti et al. NATURE BIOTECHNOLOGY
- Eradication of B-lineage cells and regression of lymphoma in a patient treated with autologous T cells genetically engineered to recognize CD19
- (2010) J. N. Kochenderfer et al. BLOOD
- Exosomes: Extracellular organelles important in intercellular communication
- (2010) Suresh Mathivanan et al. Journal of Proteomics
- Trastuzumab in combination with chemotherapy versus chemotherapy alone for treatment of HER2-positive advanced gastric or gastro-oesophageal junction cancer (ToGA): a phase 3, open-label, randomised controlled trial
- (2010) Yung-Jue Bang et al. LANCET
- Multiple Drug Resistance Mechanisms in Cancer
- (2010) Bruce C. Baguley MOLECULAR BIOTECHNOLOGY
- Molecular mechanism of multivesicular body biogenesis by ESCRT complexes
- (2010) Thomas Wollert et al. NATURE
- Exosome secreted by MSC reduces myocardial ischemia/reperfusion injury
- (2010) Ruenn Chai Lai et al. Stem Cell Research
- The ESCRT machinery in endosomal sorting of ubiquitylated membrane proteins
- (2009) Camilla Raiborg et al. NATURE
- Mesenchymal Stromal Cells â Current Understanding and Clinical Status
- (2009) H. K. Salem et al. STEM CELLS
- Ceramide Triggers Budding of Exosome Vesicles into Multivesicular Endosomes
- (2008) K. Trajkovic et al. SCIENCE
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