Lysosome docking to WIPI1 rings and ER-connected phagophores occurs during DNAJB12- and GABARAP-dependent selective autophagy of misfolded P23H-rhodopsin

ER-Phagy, ER Homeostasis, and ER Quality Control: Implications for Disease

(2021) Susan Ferro-Novick et al.   TRENDS IN BIOCHEMICAL SCIENCES

WIPI1 promotes fission of endosomal transport carriers and formation of autophagosomes through distinct mechanisms

(2021) Maria Giovanna De Leo et al.   Autophagy

DNAJB12 and Hsp70 Triage Arrested Intermediates of N1303K-CFTR for ER Associated-Autophagy

(2021) Lihua He et al.   MOLECULAR BIOLOGY OF THE CELL

Membrane protein folding and quality control

(2021) Ben P. Phillips et al.   CURRENT OPINION IN STRUCTURAL BIOLOGY

Mechanistic insights in recov-ER-phagy: micro-ER-phagy to recover from stress

(2020) Marisa Loi et al.   Autophagy

ER-Phagy: Quality Control and Turnover of Endoplasmic Reticulum

(2020) Haruka Chino et al.   TRENDS IN CELL BIOLOGY

Protrudin-mediated ER–endosome contact sites promote MT1-MMP exocytosis and cell invasion

(2020) Nina Marie Pedersen et al.   JOURNAL OF CELL BIOLOGY

Therapy in Rhodopsin-Mediated Autosomal Dominant Retinitis Pigmentosa

(2020) Da Meng et al.   MOLECULAR THERAPY

The proteostasis network and its decline in ageing

(2019) Mark S. Hipp et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Spatiotemporal Control of ULK1 Activation by NDP52 and TBK1 during Selective Autophagy

(2019) Jose Norberto S. Vargas et al.   MOLECULAR CELL

The Cargo Receptor NDP52 Initiates Selective Autophagy by Recruiting the ULK Complex to Cytosol-Invading Bacteria

(2019) Benjamin J. Ravenhill et al.   MOLECULAR CELL

ATL3 Is a Tubular ER-Phagy Receptor for GABARAP-Mediated Selective Autophagy

(2019) Qingzhou Chen et al.   CURRENT BIOLOGY

Proteasomal and lysosomal clearance of faulty secretory proteins: ER-associated degradation (ERAD) and ER-to-lysosome-associated degradation (ERLAD) pathways

(2019) Ilaria Fregno et al.   CRITICAL REVIEWS IN BIOCHEMISTRY AND MOLECULAR BIOLOGY

Emerging Principles of Selective ER Autophagy

(2019) Simon Wilkinson   JOURNAL OF MOLECULAR BIOLOGY

TEX264 Is an Endoplasmic Reticulum-Resident ATG8-Interacting Protein Critical for ER Remodeling during Nutrient Stress

(2019) Heeseon An et al.   MOLECULAR CELL

Intrinsically Disordered Protein TEX264 Mediates ER-phagy

(2019) Haruka Chino et al.   MOLECULAR CELL

Curvature induction and membrane remodeling by FAM134B reticulon homology domain assist selective ER-phagy

(2019) Ramachandra M. Bhaskara et al.   Nature Communications

Molecular determinants regulating selective binding of autophagy adapters and receptors to ATG8 proteins

(2019) Martina Wirth et al.   Nature Communications

TEX264 is a major receptor for mammalian reticulophagy

(2019) Elizabeth Delorme-Axford et al.   Autophagy

GABARAPs and LC3s have opposite roles in regulating ULK1 for autophagy induction

(2019) Douglas S. Grunwald et al.   Autophagy

Rhodopsin Oligomerization and Aggregation

(2019) Paul S.-H. Park   JOURNAL OF MEMBRANE BIOLOGY

Picky Eating at the ER-phagy Buffet

(2019) Simon Wilkinson   TRENDS IN BIOCHEMICAL SCIENCES

The molecular and cellular basis of rhodopsin retinitis pigmentosa reveals potential strategies for therapy

(2018) Dimitra Athanasiou et al.   PROGRESS IN RETINAL AND EYE RESEARCH

CellProfiler 3.0: Next-generation image processing for biology

(2018) Claire McQuin et al.   PLOS BIOLOGY

ER‐to‐lysosome‐associated degradation of proteasome‐resistant ATZ polymers occurs via receptor‐mediated vesicular transport

(2018) Ilaria Fregno et al.   EMBO JOURNAL

ESCRT‐mediated lysosome repair precedes lysophagy and promotes cell survival

(2018) Maja Radulovic et al.   EMBO JOURNAL

A selective ER‐phagy exerts procollagen quality control via a Calnexin‐FAM134B complex

(2018) Alison Forrester et al.   EMBO JOURNAL

Endoplasmic reticulum stress–induced degradation of DNAJB12 stimulates BOK accumulation and primes cancer cells for apoptosis

(2017) Pattarawut Sopha et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Systematic Analysis of Human Cells Lacking ATG8 Proteins Uncovers Roles for GABARAPs and the CCZ1/MON1 Regulator C18orf8/RMC1 in Macroautophagic and Selective Autophagic Flux

(2017) Laura Pontano Vaites et al.   MOLECULAR AND CELLULAR BIOLOGY

Tetrameric Assembly of K + Channels Requires ER-Located Chaperone Proteins

(2017) Kai Li et al.   MOLECULAR CELL

GABARAP activates ULK1 and traffics from the centrosome dependent on Golgi partners WAC and GOLGA2/GM130

(2016) Justin Joachim et al.   Autophagy

BOK Is a Non-canonical BCL-2 Family Effector of Apoptosis Regulated by ER-Associated Degradation

(2016) Fabien Llambi et al.   CELL

Recruitment of TBK1 to cytosol‐invading Salmonella induces WIPI2‐dependent antibacterial autophagy

(2016) Teresa LM Thurston et al.   EMBO JOURNAL

Mechanisms and functions of lysosome positioning

(2016) Jing Pu et al.   JOURNAL OF CELL SCIENCE

Digesting the Expanding Mechanisms of Autophagy

(2016) Nicholas T. Ktistakis et al.   TRENDS IN CELL BIOLOGY

Pharmacological inhibition of ULK1 kinase blocks mammalian target of rapamycin (mTOR)-dependent autophagy.

(2015) Katy J. Petherick et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

WIPI proteins: essential PtdIns3P effectors at the nascent autophagosome

(2015) T. Proikas-Cezanne et al.   JOURNAL OF CELL SCIENCE

Inherent Instability of the Retinitis Pigmentosa P23H Mutant Opsin

(2014) Yuanyuan Chen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

ERQC Autophagy: Yet Another Way to Die

(2014) Alexander Buchberger   MOLECULAR CELL

Quality Control Autophagy Degrades Soluble ERAD-Resistant Conformers of the Misfolded Membrane Protein GnRHR

(2014) Scott A. Houck et al.   MOLECULAR CELL

Selective VPS34 inhibitor blocks autophagy and uncovers a role for NCOA4 in ferritin degradation and iron homeostasis in vivo

(2014) William E. Dowdle et al.   NATURE CELL BIOLOGY

A Cytosolic Chaperone Complexes with Dynamic Membrane J-Proteins and Mobilizes a Nonenveloped Virus out of the Endoplasmic Reticulum

(2014) Christopher Paul Walczak et al.   PLoS Pathogens

A Novel Mammalian ER-located J-protein, DNAJB14, Can Accelerate ERAD of Misfolded Membrane Proteins

(2012) Pattarawut Sopha et al.   CELL STRUCTURE AND FUNCTION

IRE1 directs proteasomal and lysosomal degradation of misfolded rhodopsin

(2012) Wei-Chieh Chiang et al.   MOLECULAR BIOLOGY OF THE CELL

Icy: an open bioimage informatics platform for extended reproducible research

(2012) Fabrice de Chaumont et al.   NATURE METHODS

Fiji: an open-source platform for biological-image analysis

(2012) Johannes Schindelin et al.   NATURE METHODS

Hsp90-Cdc37 Chaperone Complex Regulates Ulk1- and Atg13-Mediated Mitophagy

(2011) Joung Hyuck Joo et al.   MOLECULAR CELL

Electron tomography reveals the endoplasmic reticulum as a membrane source for autophagosome formation

(2010) Mitsuko Hayashi-Nishino et al.   Autophagy

A Novel ER J-protein DNAJB12 Accelerates ER-associated Degradation of Membrane Proteins Including CFTR

(2010) Yo-hei Yamamoto et al.   CELL STRUCTURE AND FUNCTION

The endoplasmic reticulum–associated Hsp40 DNAJB12 and Hsc70 cooperate to facilitate RMA1 E3–dependent degradation of nascent CFTRΔF508

(2010) Diane E. Grove et al.   MOLECULAR BIOLOGY OF THE CELL

The origin of the autophagosomal membrane

(2010) Sharon A. Tooze et al.   NATURE CELL BIOLOGY

3D tomography reveals connections between the phagophore and endoplasmic reticulum

(2009) Päivi Ylä-Anttila et al.   Autophagy

A subdomain of the endoplasmic reticulum forms a cradle for autophagosome formation

(2009) Mitsuko Hayashi-Nishino et al.   NATURE CELL BIOLOGY

Autophagosome formation from membrane compartments enriched in phosphatidylinositol 3-phosphate and dynamically connected to the endoplasmic reticulum

(2008) Elizabeth L. Axe et al.   JOURNAL OF CELL BIOLOGY