Identification of PAX6 and NFAT4 as the Transcriptional Regulators of the Long Noncoding RNA Mrhl in Neuronal Progenitors

On the functional relevance of spatiotemporally-specific patterns of experience-dependent long noncoding RNA expression in the brain

(2021) Wei-Siang Liau et al.   RNA Biology

LncRNA-Encoded Peptide: Functions and Predicting Methods

(2021) Jiani Xing et al.   Frontiers in Oncology

PAUPAR and PAX6 sequentially regulate human embryonic stem cell cortical differentiation

(2021) Yanxin Xu et al.   NUCLEIC ACIDS RESEARCH

LncRNA Mrhl orchestrates differentiation programs in mouse embryonic stem cells through chromatin mediated regulation

(2021) Debosree Pal et al.   Stem Cell Research

When Long Noncoding Becomes Protein Coding

(2020) Corrine Corrina R. Hartford et al.   MOLECULAR AND CELLULAR BIOLOGY

The functions of long non-coding RNAs in neural stem cell proliferation and differentiation

(2020) Yanfang Zhao et al.   Cell and Bioscience

Regulation of neuronal commitment in mouse embryonic stem cells by the Reno1/Bahcc1 locus

(2020) Hadas Hezroni et al.   EMBO REPORTS

Transcriptome Analysis Identifies SenZfp536, a Sense LncRNA that Suppresses Self-renewal of Cortical Neural Progenitors

(2020) Kuan Tian et al.   Neuroscience Bulletin

Long Non-coding RNA in Neuronal Development and Neurological Disorders

(2019) Ling Li et al.   Frontiers in Genetics

Synapse-to-Nucleus Communication through NFAT Is Mediated by L-type Ca2+ Channel Ca2+ Spike Propagation to the Soma

(2019) Angela R. Wild et al.   Cell Reports

LncRNA Riken-201 and Riken-203 modulates neural development by regulating the Sox6 through sequestering miRNAs

(2019) Lei Zhang et al.   CELL PROLIFERATION

LncRNA Rik-203 contributes to anesthesia neurotoxicity via microRNA-101a-3p and GSK-3β-mediated neural differentiation

(2019) Lei Zhang et al.   Scientific Reports

Transcription factor Nrf2 induces the up-regulation of lncRNA TUG1 to promote progression and adriamycin resistance in urothelial carcinoma of the bladder

(2019) Zhulei Sun et al.   Cancer Management and Research

A balanced translocation in Kallmann Syndrome implicates a long noncoding RNA, RMST, as a GnRH neuronal regulator

(2019) Maria Stamou et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

LncRNA Neat1 mediates miR-124-induced activation of Wnt/β-catenin signaling in spinal cord neural progenitor cells

(2019) Yi Cui et al.   Stem Cell Research & Therapy

Functional Classification and Experimental Dissection of Long Noncoding RNAs

(2018) Florian Kopp et al.   CELL

An atlas of chromatin accessibility in the adult human brain

(2018) John F. Fullard et al.   GENOME RESEARCH

Antagonism between the transcription factors NANOG and OTX2 specifies rostral or caudal cell fate during neural patterning transition

(2018) Zhenghui Su et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Meis1 Coordinates Cerebellar Granule Cell Development by Regulating Pax6 Transcription, BMP Signaling and Atoh1 Degradation

(2018) Tomoo Owa et al.   JOURNAL OF NEUROSCIENCE

Long noncoding RNA Sox2ot and transcription factor YY1 co-regulate the differentiation of cortical neural progenitors by repressing Sox2

(2018) Jennifer L. Knauss et al.   Cell Death & Disease

STAT3-mediated upregulation of lncRNA HOXD-AS1 as a ceRNA facilitates liver cancer metastasis by regulating SOX4

(2017) Hui Wang et al.   Molecular Cancer

Dynamics of RNA Polymerase II Pausing and Bivalent Histone H3 Methylation during Neuronal Differentiation in Brain Development

(2017) Jiancheng Liu et al.   Cell Reports

Long noncoding RNAs: Central to nervous system development

(2016) Ronald P. Hart et al.   INTERNATIONAL JOURNAL OF DEVELOPMENTAL NEUROSCIENCE

Regulation of different human NFAT isoforms by neuronal activity

(2016) Hanna Vihma et al.   JOURNAL OF NEUROCHEMISTRY

Local regulation of gene expression by lncRNA promoters, transcription and splicing

(2016) Jesse M. Engreitz et al.   NATURE

Pax6 associates with H3K4-specific histone methyltransferases Mll1, Mll2, and Set1a and regulates H3K4 methylation at promoters and enhancers

(2016) Jian Sun et al.   Epigenetics & Chromatin

Loss of the transcription factor Meis1 prevents sympathetic neurons target-field innervation and increases susceptibility to sudden cardiac death

(2016) Fabrice Bouilloux et al.   eLife

Long Noncoding RNA Regulation of Pluripotency

(2016) Alessandro Rosa et al.   Stem Cells International

Mapping gene regulatory circuitry of Pax6 during neurogenesis

(2016) Sudhir Thakurela et al.   Cell Discovery

The Long Noncoding RNA Pnky Regulates Neuronal Differentiation of Embryonic and Postnatal Neural Stem Cells

(2015) Alexander D. Ramos et al.   Cell Stem Cell

From Discovery to Function: The Expanding Roles of Long NonCoding RNAs in Physiology and Disease

(2015) Miao Sun et al.   ENDOCRINE REVIEWS

The landscape of long noncoding RNAs in the human transcriptome

(2015) Matthew K Iyer et al.   NATURE GENETICS

Mechanisms of Long Non-coding RNAs in Mammalian Nervous System Development, Plasticity, Disease, and Evolution

(2015) James A. Briggs et al.   NEURON

Identification ofin vivoDNA-binding mechanisms of Pax6 and reconstruction of Pax6-dependent gene regulatory networks during forebrain and lens development

(2015) Jian Sun et al.   NUCLEIC ACIDS RESEARCH

Mechanism of Wnt signaling induced down regulation ofmrhllong non-coding RNA in mouse spermatogonial cells

(2015) Vijay Suresh Akhade et al.   NUCLEIC ACIDS RESEARCH

Spatiotemporal expression and transcriptional perturbations by long noncoding RNAs in the mouse brain

(2015) Loyal A. Goff et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Transcriptome analyses of adult mouse brain reveal enrichment of lncRNAs in specific brain regions and neuronal populations

(2015) Beena M. Kadakkuzha et al.   Frontiers in Cellular Neuroscience

Genome wide chromatin occupancy ofmrhlRNA and its role in gene regulation in mouse spermatogonial cells

(2015) Vijay Suresh Akhade et al.   RNA Biology

Regulation of lncRNA expression

(2014) Zhuomin Wu et al.   CELLULAR & MOLECULAR BIOLOGY LETTERS

Unlocking epigenetic codes in neurogenesis

(2014) B. Yao et al.   GENES & DEVELOPMENT

The role of long non-coding RNAs in neurodevelopment, brain function and neurological disease

(2014) T. C. Roberts et al.   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

The long non-coding RNA Dali is an epigenetic regulator of neural differentiation

(2014) Vladislava Chalei et al.   eLife

Recent advances in the involvement of long non-coding RNAs in neural stem cell biology and brain pathophysiology

(2014) Daphne Antoniou et al.   Frontiers in Physiology

The Long Noncoding RNA RMST Interacts with SOX2 to Regulate Neurogenesis

(2013) Shi-Yan Ng et al.   MOLECULAR CELL

JASPAR 2014: an extensively expanded and updated open-access database of transcription factor binding profiles

(2013) Anthony Mathelier et al.   NUCLEIC ACIDS RESEARCH

Involvement of Crosstalk between Oct4 and Meis1a in Neural Cell Fate Decision

(2013) Takeyuki Yamada et al.   PLoS One

Pax6 Interactions with Chromatin and Identification of Its Novel Direct Target Genes in Lens and Forebrain

(2013) Qing Xie et al.   PLoS One

Identification and Characterization of Long Non-Coding RNAs Related to Mouse Embryonic Brain Development from Available Transcriptomic Data

(2013) Jie Lv et al.   PLoS One

GPMiner: an integrated system for mining combinatorial cis-regulatory elements in mammalian gene group

(2012) Tzong-Yi Lee et al.   BMC GENOMICS

The GENCODE v7 catalog of human long noncoding RNAs: Analysis of their gene structure, evolution, and expression

(2012) T. Derrien et al.   GENOME RESEARCH

Posttranscriptional Gene Regulation by Long Noncoding RNA

(2012) Je-Hyun Yoon et al.   JOURNAL OF MOLECULAR BIOLOGY

mrhl RNA, a Long Noncoding RNA, Negatively Regulates Wnt Signaling through Its Protein Partner Ddx5/p68 in Mouse Spermatogonial Cells

(2012) G. Arun et al.   MOLECULAR AND CELLULAR BIOLOGY

Generation of Regionally Specified Neural Progenitors and Functional Neurons from Human Embryonic Stem Cells under Defined Conditions

(2012) Agnete Kirkeby et al.   Cell Reports

FIMO: scanning for occurrences of a given motif

(2011) Charles E. Grant et al.   BIOINFORMATICS

A novel function of the proneural factor Ascl1 in progenitor proliferation identified by genome-wide characterization of its targets

(2011) D. S. Castro et al.   GENES & DEVELOPMENT

The Orchestration of Mammalian Tissue Morphogenesis through a Series of Coherent Feed-forward Loops

(2011) Qing Xie et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Long noncoding RNAs and human disease

(2011) Orly Wapinski et al.   TRENDS IN CELL BIOLOGY

Role of H3K27 methylation in the regulation of lncRNA expression

(2010) Susan C Wu et al.   CELL RESEARCH

Essential Roles of Notch Signaling in Maintenance of Neural Stem Cells in Developing and Adult Brains

(2010) I. Imayoshi et al.   JOURNAL OF NEUROSCIENCE

Rapid in situ codetection of noncoding RNAs and proteins in cells and formalin-fixed paraffin-embedded tissue sections without protease treatment

(2010) Mariàngels de Planell-Saguer et al.   Nature Protocols

Conserved long noncoding RNAs transcriptionally regulated by Oct4 and Nanog modulate pluripotency in mouse embryonic stem cells

(2009) J. Sheik Mohamed et al.   RNA

The Level of the Transcription Factor Pax6 Is Essential for Controlling the Balance between Neural Stem Cell Self-Renewal and Neurogenesis

(2009) Stephen N. Sansom et al.   PLoS Genetics

Long noncoding RNAs in mouse embryonic stem cell pluripotency and differentiation

(2008) M. E. Dinger et al.   GENOME RESEARCH

Specific expression of long noncoding RNAs in the mouse brain

(2008) T. R. Mercer et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A novel noncoding RNA processed by Drosha is restricted to nucleus in mouse

(2008) G. Ganesan et al.   RNA