Pax6 associates with H3K4-specific histone methyltransferases Mll1, Mll2, and Set1a and regulates H3K4 methylation at promoters and enhancers

PAX6: 25th anniversary and more to learn

(2017) Ales Cvekl et al.   EXPERIMENTAL EYE RESEARCH

Pioneer transcription factors, chromatin dynamics, and cell fate control

(2016) Kenneth S Zaret et al.   CURRENT OPINION IN GENETICS & DEVELOPMENT

Chromatin remodeling enzyme Snf2h regulates embryonic lens differentiation and denucleation

(2016) Shuying He et al.   DEVELOPMENT

H3K4 Methyltransferase Set1a Is A Key Oct4 Coactivator Essential for Generation of Oct4 Positive Inner Cell Mass

(2016) Lan Fang et al.   STEM CELLS

Rebalancing gene haploinsufficiency in vivo by targeting chromatin

(2016) Filomena Gabriella Fulcoli et al.   Nature Communications

MLL3 and MLL4 Methyltransferases Bind to the MAFA and MAFB Transcription Factors to Regulate Islet β-Cell Function

(2015) David W. Scoville et al.   DIABETES

Molecular characterization of mouse lens epithelial cell lines and their suitability to study RNA granules and cataract associated genes

(2015) Anne M. Terrell et al.   EXPERIMENTAL EYE RESEARCH

Early enhancer establishment and regulatory locus complexity shape transcriptional programs in hematopoietic differentiation

(2015) Alvaro J González et al.   NATURE GENETICS

Identification ofin vivoDNA-binding mechanisms of Pax6 and reconstruction of Pax6-dependent gene regulatory networks during forebrain and lens development

(2015) Jian Sun et al.   NUCLEIC ACIDS RESEARCH

DNA-mediated cooperativity facilitates the co-selection of cryptic enhancer sequences by SOX2 and PAX6 transcription factors

(2015) Kamesh Narasimhan et al.   NUCLEIC ACIDS RESEARCH

PITX2 associates with PTIP-containing histone H3 lysine 4 methyltransferase complex

(2014) Yan Liu et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Looping Back to Leap Forward: Transcription Enters a New Era

(2014) Michael Levine et al.   CELL

Anp32e, a higher eukaryotic histone chaperone directs preferential recognition for H2A.Z

(2014) Zhuo Mao et al.   CELL RESEARCH

Mll2 is required for H3K4 trimethylation on bivalent promoters in embryonic stem cells, whereas Mll1 is redundant

(2014) S. Denissov et al.   DEVELOPMENT

The cellular and molecular mechanisms of vertebrate lens development

(2014) A. Cvekl et al.   DEVELOPMENT

Pax genes: regulators of lineage specification and progenitor cell maintenance

(2014) J. A. Blake et al.   DEVELOPMENT

Histone variants: dynamic punctuation in transcription

(2014) C. M. Weber et al.   GENES & DEVELOPMENT

Pioneer transcription factors in cell reprogramming

(2014) Makiko Iwafuchi-Doi et al.   GENES & DEVELOPMENT

H3K4me2 reliably defines transcription factor binding regions in different cells

(2014) Ying Wang et al.   GENOMICS

Epigenomic analysis of primary human T cells reveals enhancers associated with TH2 memory cell differentiation and asthma susceptibility

(2014) Grégory Seumois et al.   NATURE IMMUNOLOGY

Otx2 ChIP-seq Reveals Unique and Redundant Functions in the Mature Mouse Retina

(2014) Alexander Samuel et al.   PLoS One

Enhancer RNAs and regulated transcriptional programs

(2014) Michael T.Y. Lam et al.   TRENDS IN BIOCHEMICAL SCIENCES

Chromatin accessibility: a window into the genome

(2014) Maria Tsompana et al.   Epigenetics & Chromatin

Otx2 and Oct4 Drive Early Enhancer Activation during Embryonic Stem Cell Transition from Naive Pluripotency

(2014) Shen-Hsi Yang et al.   Cell Reports

PAX6 Regulates Melanogenesis in the Retinal Pigmented Epithelium through Feed-Forward Regulatory Interactions with MITF

(2014) Shaul Raviv et al.   PLoS Genetics

The BAF Complex Interacts with Pax6 in Adult Neural Progenitors to Establish a Neurogenic Cross-Regulatory Transcriptional Network

(2013) Jovica Ninkovic et al.   Cell Stem Cell

Functional dissection of the paired domain of Pax6 reveals molecular mechanisms of coordinating neurogenesis and proliferation

(2013) T. Walcher et al.   DEVELOPMENT

Chromatin Regulation by BAF170 Controls Cerebral Cortical Size and Thickness

(2013) Tran Cong Tuoc et al.   DEVELOPMENTAL CELL

Quantitative Dissection and Stoichiometry Determination of the Human SET1/MLL Histone Methyltransferase Complexes

(2013) R. van Nuland et al.   MOLECULAR AND CELLULAR BIOLOGY

Modification of Enhancer Chromatin: What, How, and Why?

(2013) Eliezer Calo et al.   MOLECULAR CELL

Histone posttranslational modifications and cell fate determination: lens induction requires the lysine acetyltransferases CBP and p300

(2013) Louise Wolf et al.   NUCLEIC ACIDS RESEARCH

RefSeq: an update on mammalian reference sequences

(2013) Kim D. Pruitt et al.   NUCLEIC ACIDS RESEARCH

Pax6 Regulates Gene Expression in the Vertebrate Lens through miR-204

(2013) Ohad Shaham et al.   PLoS Genetics

WRAD: enabler of the SET1-family of H3K4 methyltransferases

(2012) P. Ernst et al.   Briefings in Functional Genomics

Pax3/7BP Is a Pax7- and Pax3-Binding Protein that Regulates the Proliferation of Muscle Precursor Cells by an Epigenetic Mechanism

(2012) Yarui Diao et al.   Cell Stem Cell

The Wasp System: An open source environment for managing and analyzing genomic data

(2012) Andrew S. McLellan et al.   GENOMICS

An integrated encyclopedia of DNA elements in the human genome

(2012)   NATURE

Transcription factors: from enhancer binding to developmental control

(2012) François Spitz et al.   NATURE REVIEWS GENETICS

Pax6: A multi-level regulator of ocular development

(2012) Ohad Shaham et al.   PROGRESS IN RETINAL AND EYE RESEARCH

MEME-ChIP: motif analysis of large DNA datasets

(2011) Philip Machanick et al.   BIOINFORMATICS

The mechanism of lens placode formation: A case of matrix-mediated morphogenesis

(2011) Jie Huang et al.   DEVELOPMENTAL BIOLOGY

The role of Pax6 in forebrain development

(2011) Petrina A. Georgala et al.   Developmental Neurobiology

Pioneer transcription factors: establishing competence for gene expression

(2011) K. S. Zaret et al.   GENES & DEVELOPMENT

The Orchestration of Mammalian Tissue Morphogenesis through a Series of Coherent Feed-forward Loops

(2011) Qing Xie et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Protein Arginine Methyltransferase Prmt5-Mep50 Methylates Histones H2A and H4 and the Histone Chaperone Nucleoplasmin inXenopus laevisEggs

(2011) Carola Wilczek et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Mapping and analysis of chromatin state dynamics in nine human cell types

(2011) Jason Ernst et al.   NATURE

Pfizer reaches out to academia—again

(2011) Mark Ratner   NATURE BIOTECHNOLOGY

BEDTools: a flexible suite of utilities for comparing genomic features

(2010) Aaron R. Quinlan et al.   BIOINFORMATICS

A unique H3K4me2 profile marks tissue-specific gene regulation

(2010) A. Pekowska et al.   GENOME RESEARCH

A Novel Non-SET Domain Multi-subunit Methyltransferase Required for Sequential Nucleosomal Histone H3 Methylation by the Mixed Lineage Leukemia Protein-1 (MLL1) Core Complex

(2010) Anamika Patel et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Lens Fiber Cell Differentiation and Denucleation Are Disrupted through Expression of the N-Terminal Nuclear Receptor Box of Ncoa6 and Result in p53-dependent and p53-independent Apoptosis

(2010) Wei-Lin Wang et al.   MOLECULAR BIOLOGY OF THE CELL

Emerging properties of animal gene regulatory networks

(2010) Eric H. Davidson   NATURE

CpG islands influence chromatin structure via the CpG-binding protein Cfp1

(2010) John P. Thomson et al.   NATURE

Mediator and cohesin connect gene expression and chromatin architecture

(2010) Michael H. Kagey et al.   NATURE

seqMINER: an integrated ChIP-seq data interpretation platform

(2010) Tao Ye et al.   NUCLEIC ACIDS RESEARCH

Chromatin remodeling enzyme Brg1 is required for mouse lens fiber cell terminal differentiation and its denucleation

(2010) Shuying He et al.   Epigenetics & Chromatin

A clustering approach for identification of enriched domains from histone modification ChIP-Seq data

(2009) Chongzhi Zang et al.   BIOINFORMATICS

Pax6 dosage requirements in iris and ciliary body differentiation

(2009) Noa Davis et al.   DEVELOPMENTAL BIOLOGY

Spatial and temporal regulation of Wnt/β-catenin signaling is essential for development of the retinal pigment epithelium

(2009) Naoko Fujimura et al.   DEVELOPMENTAL BIOLOGY

ChIP-seq accurately predicts tissue-specific activity of enhancers

(2009) Axel Visel et al.   NATURE

Identification of Pax6-Dependent Gene Regulatory Networks in the Mouse Lens

(2009) Louise V. Wolf et al.   PLoS One

Ultrafast and memory-efficient alignment of short DNA sequences to the human genome

(2009) Ben Langmead et al.   GENOME BIOLOGY

Model-based Analysis of ChIP-Seq (MACS)

(2008) Yong Zhang et al.   GENOME BIOLOGY