Effect of common genetic variants on the risk of cirrhosis in non‐alcoholic fatty liver disease during 20 years of follow‐up

Non-invasive tests accurately stratify patients with NAFLD based on their risk of liver-related events

(2022) Jerome Boursier et al.   JOURNAL OF HEPATOLOGY

Nordic Health Registry-Based Research: A Review of Health Care Systems and Key Registries

(2021) Kristina Laugesen et al.   Clinical Epidemiology

Metabolic and genetic determinants for progression to severe liver disease in subjects with obesity from the UK Biobank

(2021) Antonio De Vincentis et al.   INTERNATIONAL JOURNAL OF OBESITY

Genetic Risk Factors and Disease Modifiers of Nonalcoholic Steatohepatitis

(2020) Julia Kozlitina   GASTROENTEROLOGY CLINICS OF NORTH AMERICA

Genetic Susceptibility to Chronic Liver Disease in Individuals from Pakistan

(2020) Asad Mehmood Raja et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Genome-wide association study of non-alcoholic fatty liver and steatohepatitis in a histologically-characterised cohort

(2020) Quentin M. Anstee et al.   JOURNAL OF HEPATOLOGY

A common variant in PNPLA3 is associated with age at diagnosis of NAFLD in patients from a multi-ethnic biobank

(2020) Ryan W. Walker et al.   JOURNAL OF HEPATOLOGY

PNPLA3 rs738409 C>G Variant Predicts Fibrosis Progression by Noninvasive Tools in Nonalcoholic Fatty Liver Disease

(2020) Grazia Pennisi et al.   Clinical Gastroenterology and Hepatology

Validity of administrative codes associated with cirrhosis in Sweden

(2020) Bonnie Bengtsson et al.   SCANDINAVIAN JOURNAL OF GASTROENTEROLOGY

The Global Epidemiology of NAFLD and NASH in Patients with type 2 diabetes: A Systematic Review and Meta-analysis

(2019) Zobair M. Younossi et al.   JOURNAL OF HEPATOLOGY

Association Between PNPLA3 rs738409 C>G Variant and Liver-Related Outcomes in Patients with Non-alcoholic Fatty Liver Disease

(2019) Stefania Grimaudo et al.   Clinical Gastroenterology and Hepatology

PNPLA3 I148M and liver fat and fibrosis scores predict liver disease mortality in the United States population

(2019) Aynur Unalp‐Arida et al.   HEPATOLOGY

The rs626283 Variant in the MBOAT7 Gene is Associated with Insulin Resistance and Fatty Liver in Caucasian Obese Youth

(2018) Giuseppina R Umano et al.   AMERICAN JOURNAL OF GASTROENTEROLOGY

The role of PNPLA3 in health and disease

(2018) Piero Pingitore et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Lack of evidence supporting a role of TMC4-rs641738 missense variant—MBOAT7- intergenic downstream variant—in the Susceptibility to Nonalcoholic Fatty Liver Disease

(2018) Silvia Sookoian et al.   Scientific Reports

HSD17B13 is a Hepatic Retinol Dehydrogenase Associated with Histological Features of Non-Alcoholic Fatty Liver Disease

(2018) Yanling Ma et al.   HEPATOLOGY

The Swedish cause of death register

(2017) Hannah Louise Brooke et al.   EUROPEAN JOURNAL OF EPIDEMIOLOGY

Fibrosis stage but not NASH predicts mortality and time to development of severe liver disease in biopsy-proven NAFLD

(2017) Hannes Hagström et al.   JOURNAL OF HEPATOLOGY

Causal relationship of hepatic fat with liver damage and insulin resistance in nonalcoholic fatty liver

(2017) P. Dongiovanni et al.   JOURNAL OF INTERNAL MEDICINE

Introduction to the Analysis of Survival Data in the Presence of Competing Risks

(2016) Peter C. Austin et al.   CIRCULATION

The MBOAT7-TMC4 Variant rs641738 Increases Risk of Nonalcoholic Fatty Liver Disease in Individuals of European Descent

(2016) Rosellina Margherita Mancina et al.   GASTROENTEROLOGY

Relationships between Genetic Variations of PNPLA3, TM6SF2 and Histological Features of Nonalcoholic Fatty Liver Disease in Japan

(2016) Norio Akuta et al.   Gut and Liver

Global epidemiology of nonalcoholic fatty liver disease-Meta-analytic assessment of prevalence, incidence, and outcomes

(2016) Zobair M. Younossi et al.   HEPATOLOGY

The MBOAT7 variant rs641738 alters hepatic phosphatidylinositols and increases severity of non-alcoholic fatty liver disease in humans

(2016) Panu K. Luukkonen et al.   JOURNAL OF HEPATOLOGY

EASL–EASD–EASO Clinical Practice Guidelines for the management of non-alcoholic fatty liver disease

(2016)   JOURNAL OF HEPATOLOGY

SAF score and mortality in NAFLD after up to 41 years of follow-up

(2016) Hannes Hagström et al.   SCANDINAVIAN JOURNAL OF GASTROENTEROLOGY

Genetic factors that affect nonalcoholic fatty liver disease: A systematic clinical review

(2016) Tyler J Severson et al.   WORLD JOURNAL OF GASTROENTEROLOGY

GCKR polymorphism influences liver fat content in patients with type 2 diabetes

(2015) Jean-Michel Petit et al.   ACTA DIABETOLOGICA

Fibrosis Progression in Nonalcoholic Fatty Liver vs Nonalcoholic Steatohepatitis: A Systematic Review and Meta-analysis of Paired-Biopsy Studies

(2015) Siddharth Singh et al.   Clinical Gastroenterology and Hepatology

Heritability of Hepatic Fibrosis and Steatosis Based on a Prospective Twin Study

(2015) Rohit Loomba et al.   GASTROENTEROLOGY

Transmembrane 6 superfamily member 2 gene variant disentangles nonalcoholic steatohepatitis from cardiovascular disease

(2015) Paola Dongiovanni et al.   HEPATOLOGY

Genetic variation in transmembrane 6 superfamily member 2 and the risk of nonalcoholic fatty liver disease and histological disease severity

(2015) Silvia Sookoian et al.   HEPATOLOGY

Evidence of NAFLD progression from steatosis to fibrosing-steatohepatitis using paired biopsies: Implications for prognosis and clinical management

(2015) Stuart McPherson et al.   JOURNAL OF HEPATOLOGY

Expanding consensus in portal hypertension

(2015) Roberto de Franchis   JOURNAL OF HEPATOLOGY

Modulation of Glucokinase Regulatory Protein: A Double-Edged Sword?

(2015) Martijn C.G.J. Brouwers et al.   TRENDS IN MOLECULAR MEDICINE

Influence of the PNPLA3 rs738409 Polymorphism on Non-Alcoholic Fatty Liver Disease and Renal Function among Normal Weight Subjects

(2015) Kentaro Oniki et al.   PLoS One

Utility and appropriateness of the fatty liver inhibition of progression (FLIP) algorithm and steatosis, activity, and fibrosis (SAF) score in the evaluation of biopsies of nonalcoholic fatty liver disease

(2014) Pierre Bedossa et al.   HEPATOLOGY

Exome-wide association study identifies a TM6SF2 variant that confers susceptibility to nonalcoholic fatty liver disease

(2014) Julia Kozlitina et al.   NATURE GENETICS

Glucokinase Regulatory Protein Gene Polymorphism Affects Liver Fibrosis in Non-Alcoholic Fatty Liver Disease

(2014) Salvatore Petta et al.   PLoS One

TM6SF2 rs58542926 influences hepatic fibrosis progression in patients with non-alcoholic fatty liver disease

(2014) Yang-Lin Liu et al.   Nature Communications

Genetic Predisposition in NAFLD and NASH: Impact on Severity of Liver Disease and Response to Treatment

(2013) Paola Dongiovanni et al.   CURRENT PHARMACEUTICAL DESIGN

External review and validation of the Swedish national inpatient register

(2011) Jonas F Ludvigsson et al.   BMC PUBLIC HEALTH

Variant in the glucokinase regulatory protein (GCKR) gene is associated with fatty liver in obese children and adolescents

(2011) Nicola Santoro et al.   HEPATOLOGY

Meta-analysis of the influence of I148M variant of patatin-like phospholipase domain containing 3 gene (PNPLA3) on the susceptibility and histological severity of nonalcoholic fatty liver disease

(2011) Silvia Sookoian et al.   HEPATOLOGY

Expression and Characterization of a PNPLA3 Protein Isoform (I148M) Associated with Nonalcoholic Fatty Liver Disease

(2011) Yongcheng Huang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Genome-Wide Association Analysis Identifies Variants Associated with Nonalcoholic Fatty Liver Disease That Have Distinct Effects on Metabolic Traits

(2011) Elizabeth K. Speliotes et al.   PLoS Genetics

Homozygosity for the patatin-like phospholipase-3/adiponutrin I148M polymorphism influences liver fibrosis in patients with nonalcoholic fatty liver disease

(2010) Luca Valenti et al.   HEPATOLOGY

The Swedish personal identity number: possibilities and pitfalls in healthcare and medical research

(2009) Jonas F. Ludvigsson et al.   EUROPEAN JOURNAL OF EPIDEMIOLOGY

The P446L variant in GCKR associated with fasting plasma glucose and triglyceride levels exerts its effect through increased glucokinase activity in liver

(2009) Nicola L. Beer et al.   HUMAN MOLECULAR GENETICS

The completeness of the Swedish Cancer Register – a sample survey for year 1998

(2008) Lotti Barlow et al.   ACTA ONCOLOGICA

Genetic variation in PNPLA3 confers susceptibility to nonalcoholic fatty liver disease

(2008) Stefano Romeo et al.   NATURE GENETICS