Variant in the glucokinase regulatory protein (GCKR) gene is associated with fatty liver in obese children and adolescents

Association of Genetic Loci With Glucose Levels in Childhood and Adolescence: A Meta-Analysis of Over 6,000 Children

(2011) A. Barker et al.   DIABETES

Expression and Characterization of a PNPLA3 Protein Isoform (I148M) Associated with Nonalcoholic Fatty Liver Disease

(2011) Yongcheng Huang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The APOC3 T-455C and C-482T promoter region polymorphisms are not associated with the severity of liver damage independently of PNPLA3 I148M genotype in patients with nonalcoholic fatty liver

(2011) Luca Valenti et al.   JOURNAL OF HEPATOLOGY

Lack of effect of apolipoprotein C3 polymorphisms on indices of liver steatosis, lipid profile and insulin resistance in obese Southern Europeans

(2011) Federica Sentinelli et al.   Lipids in Health and Disease

Genome-Wide Association Analysis Identifies Variants Associated with Nonalcoholic Fatty Liver Disease That Have Distinct Effects on Metabolic Traits

(2011) Elizabeth K. Speliotes et al.   PLoS Genetics

Ethnic differences in lipoprotein subclasses in obese adolescents: importance of liver and intraabdominal fat accretion

(2010) Ebe D’Adamo et al.   AMERICAN JOURNAL OF CLINICAL NUTRITION

TRIB1 and GCKR Polymorphisms, Lipid Levels, and Risk of Ischemic Heart Disease in the General Population

(2010) Anette Varbo et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

GCKR gene functional variants in type 2 diabetes and metabolic syndrome: do the rare variants associate with increased carotid intima-media thickness?

(2010) Márton Mohás et al.   Cardiovascular Diabetology

Unravelling the pathogenesis of fatty liver disease: patatin-like phospholipase domain-containing 3 protein

(2010) Stefano Romeo et al.   CURRENT OPINION IN LIPIDOLOGY

Association of a Fasting Glucose Genetic Risk Score With Subclinical Atherosclerosis: The Atherosclerosis Risk in Communities (ARIC) Study

(2010) L. J. Rasmussen-Torvik et al.   DIABETES

Central Role of Fatty Liver in the Pathogenesis of Insulin Resistance in Obese Adolescents

(2010) E. D'Adamo et al.   DIABETES CARE

Genetic variants regulating insulin receptor signalling are associated with the severity of liver damage in patients with non-alcoholic fatty liver disease

(2010) P. Dongiovanni et al.   GUT

Dissociation between APOC3 variants, hepatic triglyceride content and insulin resistance

(2010) Julia Kozlitina et al.   HEPATOLOGY

Patatin-like phospholipase domain-containing 3 and the pathogenesis and progression of pediatric nonalcoholic fatty liver disease

(2010) Jeffrey D. Browning et al.   HEPATOLOGY

Patatin-like phospholipase domain-containing 3/adiponutrin deficiency in mice is not associated with fatty liver disease

(2010) Weiqin Chen et al.   HEPATOLOGY

I148M patatin-like phospholipase domain-containing 3 gene variant and severity of pediatric nonalcoholic fatty liver disease

(2010) Luca Valenti et al.   HEPATOLOGY

A common variant in the patatin-like phospholipase 3 gene (PNPLA3) is associated with fatty liver disease in obese children and adolescents

(2010) Nicola Santoro et al.   HEPATOLOGY

Glucokinase-activating GCKR Polymorphisms Increase Plasma Levels of Triglycerides and Free Fatty Acids, but do not Elevate Cardiovascular Risk in the Ludwigshafen Risk and Cardiovascular Health Study

(2010) D. H. Kozian et al.   HORMONE AND METABOLIC RESEARCH

Apolipoprotein C3 Gene Variants in Nonalcoholic Fatty Liver Disease

(2010) Kitt Falk Petersen et al.   NEW ENGLAND JOURNAL OF MEDICINE

A feed-forward loop amplifies nutritional regulation of PNPLA3

(2010) Yongcheng Huang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The natural history of non-alcoholic fatty liver disease in children: a follow-up study for up to 20 years

(2009) A E Feldstein et al.   GUT

The P446L variant in GCKR associated with fasting plasma glucose and triglyceride levels exerts its effect through increased glucokinase activity in liver

(2009) Nicola L. Beer et al.   HUMAN MOLECULAR GENETICS

A Sequence Variation (I148M) in PNPLA3 Associated with Nonalcoholic Fatty Liver Disease Disrupts Triglyceride Hydrolysis

(2009) Shaoqing He et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Cardiovascular Risk Factors and the Metabolic Syndrome in Pediatric Nonalcoholic Fatty Liver Disease

(2008) Jeffrey B. Schwimmer et al.   CIRCULATION

Genetic variation in PNPLA3 confers susceptibility to nonalcoholic fatty liver disease

(2008) Stefano Romeo et al.   NATURE GENETICS

Newly identified loci that influence lipid concentrations and risk of coronary artery disease

(2008) Cristen J Willer et al.   NATURE GENETICS

Metabolic Syndrome Rates in United States Adolescents, from the National Health and Nutrition Examination Survey, 1999–2002

(2007) Stephen Cook et al.   JOURNAL OF PEDIATRICS