Phosphoglycerate mutase 5 initiates inflammation in acute kidney injury by triggering mitochondrial DNA release by dephosphorylating the pro-apoptotic protein Bax
Published 2022 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Phosphoglycerate mutase 5 initiates inflammation in acute kidney injury by triggering mitochondrial DNA release by dephosphorylating the pro-apoptotic protein Bax
Authors
Keywords
-
Journal
KIDNEY INTERNATIONAL
Volume -, Issue -, Pages -
Publisher
Elsevier BV
Online
2022-09-08
DOI
10.1016/j.kint.2022.08.022
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- A novel role of KEAP1/PGAM5 complex: ROS sensor for inducing mitophagy
- (2021) Akbar Zeb et al. Redox Biology
- TDP-43 Triggers Mitochondrial DNA Release via mPTP to Activate cGAS/STING in ALS
- (2020) Chien-Hsiung Yu et al. CELL
- Prevention of rhabdomyolysis-induced acute kidney injury - A DASAIM/DSIT clinical practice guideline
- (2019) Jens Michelsen et al. ACTA ANAESTHESIOLOGICA SCANDINAVICA
- Clearance of damaged mitochondria via mitophagy is important to the protective effect of ischemic preconditioning in kidneys
- (2019) Man J. Livingston et al. Autophagy
- The cleavage of gasdermin D by caspase-11 promotes tubular epithelial cell pyroptosis and urinary IL-18 excretion in acute kidney injury
- (2019) Naijun Miao et al. KIDNEY INTERNATIONAL
- PHB2 (prohibitin 2) promotes PINK1-PRKN/Parkin-dependent mitophagy by the PARL-PGAM5-PINK1 axis
- (2019) Chaojun Yan et al. Autophagy
- Mitochondrial translocation of cyclin C stimulates intrinsic apoptosis through Bax recruitment
- (2019) Jan Jezek et al. EMBO REPORTS
- Structure-activity relationship studies on Bax activator SMBA1 for the treatment of ER-positive and triple-negative breast cancer
- (2019) Gang Liu et al. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
- Mitochondrial Damage and Activation of the STING Pathway Lead to Renal Inflammation and Fibrosis
- (2019) Ki Wung Chung et al. Cell Metabolism
- Influenza A virus M2 protein triggers mitochondrial DNA-mediated antiviral immune responses
- (2019) Miyu Moriyama et al. Nature Communications
- Mitochondrial Damage Causes Inflammation via cGAS-STING Signaling in Acute Kidney Injury
- (2019) Hiroshi Maekawa et al. Cell Reports
- PINK1-PRKN/PARK2 pathway of mitophagy is activated to protect against renal ischemia-reperfusion injury
- (2018) Chengyuan Tang et al. Autophagy
- Phosphorylation switches Bax from promoting to inhibiting apoptosis thereby increasing drug resistance
- (2018) Justin Kale et al. EMBO REPORTS
- Inhibitory effect of melatonin on necroptosis via repressing the Ripk3-PGAM5-CypD-mPTP pathway attenuates cardiac microvascular ischemia-reperfusion injury
- (2018) Hao Zhou et al. JOURNAL OF PINEAL RESEARCH
- BAK/BAX macropores facilitate mitochondrial herniation and mtDNA efflux during apoptosis
- (2018) Kate McArthur et al. SCIENCE
- PGAM5 regulates PINK1/Parkin-mediated mitophagy via DRP1 in CCCP-induced mitochondrial dysfunction
- (2018) Yun Sun Park et al. TOXICOLOGY LETTERS
- Urinary mitochondrial deoxyribonucleic acid associates with delayed graft function following renal transplantation
- (2018) Marcel P B Jansen et al. NEPHROLOGY DIALYSIS TRANSPLANTATION
- The proteome microenvironment determines the protective effect of preconditioning in cisplatin-induced acute kidney injury
- (2018) Martin R. Späth et al. KIDNEY INTERNATIONAL
- p38 inhibition provides anti–DNA virus immunity by regulation of USP21 phosphorylation and STING activation
- (2017) Yunfei Chen et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Apoptosis Inducing Factor Binding Protein PGAM5 Triggers Mitophagic Cell Death That Is Inhibited by the Ubiquitin Ligase Activity of X-Linked Inhibitor of Apoptosis
- (2016) Audrey M. Lenhausen et al. BIOCHEMISTRY
- PGAM5-mediated programmed necrosis of hepatocytes drives acute liver injury
- (2016) Gui-Wei He et al. GUT
- PGC1α drives NAD biosynthesis linking oxidative metabolism to renal protection
- (2016) Mei T. Tran et al. NATURE
- The Ablation of Mitochondrial Protein Phosphatase Pgam5 Confers Resistance Against Metabolic Stress
- (2016) Shiori Sekine et al. EBioMedicine
- The Mitochondrial Phosphatase PGAM5 Is Dispensable for Necroptosis but Promotes Inflammasome Activation in Macrophages
- (2015) Kenta Moriwaki et al. JOURNAL OF IMMUNOLOGY
- A Role for Tubular Necroptosis in Cisplatin-Induced AKI
- (2015) Y. Xu et al. JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY
- Mitochondrial DNA stress primes the antiviral innate immune response
- (2015) A. Phillip West et al. NATURE
- Regulation of NKT cell-mediated immune responses to tumours and liver inflammation by mitochondrial PGAM5-Drp1 signalling
- (2015) Young Jun Kang et al. Nature Communications
- Apoptotic Caspases Suppress mtDNA-Induced STING-Mediated Type I IFN Production
- (2014) Michael J. White et al. CELL
- Apoptotic Caspases Prevent the Induction of Type I Interferons by Mitochondrial DNA
- (2014) Anthony Rongvaux et al. CELL
- A Regulatory Signaling Loop Comprising the PGAM5 Phosphatase and CK2 Controls Receptor-Mediated Mitophagy
- (2014) Guo Chen et al. MOLECULAR CELL
- The Mitochondrial Phosphatase PGAM5 Functions at the Convergence Point of Multiple Necrotic Death Pathways
- (2012) Zhigao Wang et al. CELL
- Rhomboid Protease PARL Mediates the Mitochondrial Membrane Potential Loss-induced Cleavage of PGAM5
- (2012) Shiori Sekine et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Autophagy in proximal tubules protects against acute kidney injury
- (2012) Man Jiang et al. KIDNEY INTERNATIONAL
- Substrates of IAP Ubiquitin Ligases Identified with a Designed Orthogonal E3 Ligase, the NEDDylator
- (2012) Min Zhuang et al. MOLECULAR CELL
- Circulating mitochondrial DAMPs cause inflammatory responses to injury
- (2010) Qin Zhang et al. NATURE
- MITOCHONDRIAL DNA IS RELEASED BY SHOCK AND ACTIVATES NEUTROPHILS VIA P38 MAP KINASE
- (2010) Qin Zhang et al. SHOCK
Find the ideal target journal for your manuscript
Explore over 38,000 international journals covering a vast array of academic fields.
SearchCreate your own webinar
Interested in hosting your own webinar? Check the schedule and propose your idea to the Peeref Content Team.
Create Now